(n.) An inert or slightly active substance used in preparing remedies as a vehicle or medium of administration for the medicinal agents.
Example Sentences:
(1) Poly(ortho ester) bioerodible polymers are suitable materials for the topical administration of a wide variety of therapeutic agents; varying the nature and amounts of excipients physically incorporated into the polymer will vary the erosion rates from a few hours to many months.
(2) Starch particles are the smallest among the excipients studied.
(3) Concentrations of lactose (4.85 and 4.81%), fat (3.76 and 3.67%), total solids (12.57 and 12.44%), SNF (8.83 and 8.75%), casein (2.56 and 2.53%), and true protein (3.13 and 3.08%) were similar in milks from cows receiving bST and excipient, respectively.
(4) The following results were obtained in the treated forearm versus the untreated forearm (excipient alone): clinically, an increase in skin thickness; by noninvasive techniques, an increase in skin thickness, skin elasticity, skin conductance, and TEWL, and a reduction in the size of the corneocytes.
(5) The results show that the choice of the excipients is basic.
(6) safety of HPCD and its well-characterized chemical composition, suggest that this starch derivative may be a potentially useful excipient for protein drugs intended for parenteral use.
(7) However, the observation that dextran 40 formulations showed poor stability toward aggregation demonstrates that an amorphous excipient system is not a sufficient condition for stability.
(8) However, due to crystallization of the excipients during storage and the resulting decrease in Tg, samples stored at 25 degrees C were also above their Tg during much of the storage period.
(9) The effect of intramuscular injections of two multivitamin preparations, two excipient preparations without vitamins, and a placebo preparation (glycine 2.5%) on serum creatine kinase activity (S-CK) in ten healthy volunteers (three female, seven male) aged between 23 and 25 years was investigated.
(10) The method is precise and selective for nitrazepam in the presence of the tablet excipients and 2-amino-5-nitrobenzophenone, the principal hydrolysis product of nitrazepam.
(11) Solid excipients, cornstarch, and talcum powder when injected intra-arterially decreased flow, and vascular obstruction was shown angiographically.
(12) Gluconolactone contributed least to the degradation of the drug as compared to other excipients studied.
(13) Gluconolactone was evaluated as an excipient for tablets prepared by direct compression using various drugs known to be difficult to compress.
(14) Tolerance was excellent except for mild nausea, probably due to the excipients, in two patients taking nine capsules.
(15) The oral provocation test with the excipient of the commercial preparation was negative; the tolerance to Methyl-Digoxin complete.
(16) The best solvents were then used in the study of different semisolid vehicles for topical use (cetylic excipient, Beeler's base and Carbopol gel), which show different physicochemical characteristics.
(17) In contrast, no significant difference in mean survival was observed between excipient and rHTNF treated animals bearing MCA-38, -101, or -102.
(18) Excipient-treated PIC barrows exhibited faster and more efficient growth (P less than .001) and a higher capacity for carcass protein accretion (P less than .001) but similar rates of lipid deposition compared to excipient-treated NEB barrows.
(19) TIMI Phase 1.5 compared two preparations of rt-PA, the early formulation in liquid excipient ("old" rt-PA) and the new lyophilized form ("new" rt-PA).
(20) Canrenone can be determined by high-speed liquid chromatography in pharmaceutical dosage forms without interference from common excipients or degradation products.
Intercipient
Definition:
(a.) Intercepting; stopping.
(n.) One who, or that which, intercepts or stops anything on the passage.