(1) This is exemplified in lymphoma cells (chronic lymphocytic leukemia of B or T type, Sezary Syndrome, immunocytoma) that resemble mature and immunocompetent T and B cells, in T cell acute lymphoblastic leukemia (T-ALL) (equivalent to thymus cells) and in non-T ALL (corresponding to lymphoid progenitor cells in the bone marrow).
(2) Hepatitis B virus is used here to exemplify the application of recombinant DNA technology to the development of subunit vaccines and to illustrate their value in studies of other viral proteins with particular emphasis on the role of the core antigen in providing protection against viral infection and hence its potential in vaccine development.
(3) These results show for the first time the role of a specific pilus structure in colonization of the human intestine by V. cholerae O1 and exemplify the significance of a genetic regulon in pathogenesis.
(4) The method is exemplified by autoradiographs of human brain hemisphere ([ 3H]quinuclidinylbenzilate) and whole biceps muscle ([ 3H]alpha-bungarotoxin).
(5) It was thus found that the predictive efficacy of CASE was increased when it employed a combination of human and artificial intelligence, as exemplified by the CASE analysis of 'structural alerts.
(6) A comprehensive review of the world literature reveals that the systematic study of severe gender disorders--as exemplified by transsexualism--is relatively new, consisting of just over 25 years of collective experience.
(7) The disease exemplifies the validity of the Royal Veterinary College motto Venienti occurrite morbo (treat the disease at its first appearance).
(8) Further indications of the potential value of microbial metabolites are exemplified by the discovery and development of cyclosporin, to treat organ rejection, and mevinolin, a cholesterol-lowering drug.
(9) Salmonella contamination of swine and morbidity rates among the workers of swine-breeding complexes and the members of their families, as well as among the population inhabiting the zone of possible influence rendered by such complexes on the environment, have been studied as exemplified by 4 complexes for large-scale swine breeding, differing in their technology of swine raising and fattening, their systems of the purification and utilization of manure-containing sewage.
(10) Noradrenaline-beta-adrenoceptor-mediated neural plasticity in cat visual cortex exemplifies clearly established roles of the locus coeruleus system in brain function.
(11) It is argued that Western science reductionist approaches to the classification of "mass hysteria" treat it as an entity to be discovered transculturally, and in their self-fulfilling search for universals systematically exclude what does not fit within the autonomous parameters of its Western-biased culture model, exemplifying what Kleinman (1977) terms a "category fallacy."
(12) Instead we have injected vast sums of our own money to improve the playing squad and modernize LFC’s infrastructure-exemplified by the £120m advance from FSG to build the new Main Stand.
(13) The data exemplify the difficulty in reaching firm conclusions concerning associations with radiation exposure when the dependent variable exhibits a large degree of interindividual and day-of-assay variability.
(14) The paper deals with peculiarities of antioxidative activity of natural antioxidants (exemplified by ubiquinones) which permit their participation in the control of peroxidation intensity of membrane lipids.
(15) We therefore investigated the humoral and cell-mediated immune responses to mBSA in resistant mice (CBA) and susceptible mice (exemplified by C57BL) to determine whether these were associated with susceptibility to arthritis.
(16) Contamination by industrial chemicals such as polychlorinated biphenyls and polybrominated biphenyls; heavy metals such as lead, cadmium, and mercury; and pesticides such as dieldrin and chlordane exemplify the problem in feeds and the resulting problem of tissue residues in human foods.
(17) Several of these, exemplified by beta-bungarotoxin, show phospholipase A2 activity (phosphatide 2-acylhydrolase, EC 3.1.1.4) when tested in the presence of detergents.
(18) Three cases of blunt abdominal trauma are presented to exemplify the mechanism of trauma and the problems of diagnosis associated with any linear blow to the abdomen.
(19) incidence rate, absolute and relative increment of this value and the significance of a 1% increment as exemplified by this region.
(20) There are severe constraints that limit the combinations consistent with function, but the number of functionally consistent combinations observed exemplifies the plasticity of proteins.
Play
Definition:
(n.) To engage in sport or lively recreation; to exercise for the sake of amusement; to frolic; to spot.
(n.) To act with levity or thoughtlessness; to trifle; to be careless.
(n.) To contend, or take part, in a game; as, to play ball; hence, to gamble; as, he played for heavy stakes.
(n.) To perform on an instrument of music; as, to play on a flute.
(n.) To act; to behave; to practice deception.
(n.) To move in any manner; especially, to move regularly with alternate or reciprocating motion; to operate; to act; as, the fountain plays.
(n.) To move gayly; to wanton; to disport.
(n.) To act on the stage; to personate a character.
(v. t.) To put in action or motion; as, to play cannon upon a fortification; to play a trump.
(v. t.) To perform music upon; as, to play the flute or the organ.
(v. t.) To perform, as a piece of music, on an instrument; as, to play a waltz on the violin.
(v. t.) To bring into sportive or wanton action; to exhibit in action; to execute; as, to play tricks.
(v. t.) To act or perform (a play); to represent in music action; as, to play a comedy; also, to act in the character of; to represent by acting; to simulate; to behave like; as, to play King Lear; to play the woman.
(v. t.) To engage in, or go together with, as a contest for amusement or for a wager or prize; as, to play a game at baseball.
(v. t.) To keep in play, as a hooked fish, in order to land it.
(n.) Amusement; sport; frolic; gambols.
(n.) Any exercise, or series of actions, intended for amusement or diversion; a game.
(n.) The act or practice of contending for victory, amusement, or a prize, as at dice, cards, or billiards; gaming; as, to lose a fortune in play.
(n.) Action; use; employment; exercise; practice; as, fair play; sword play; a play of wit.
(n.) A dramatic composition; a comedy or tragedy; a composition in which characters are represented by dialogue and action.
(n.) The representation or exhibition of a comedy or tragedy; as, he attends ever play.
(n.) Performance on an instrument of music.
(n.) Motion; movement, regular or irregular; as, the play of a wheel or piston; hence, also, room for motion; free and easy action.
(n.) Hence, liberty of acting; room for enlargement or display; scope; as, to give full play to mirth.
Example Sentences:
(1) However, medicines have an important part to play, and it is now generally agreed that for the very poor populations medicines should be restricted to those on an 'essential drugs list' and should be made available as cheaply as possible.
(2) The data indicate that ebselen is likely to be useful in the therapy of inflammatory conditions in which reactive oxygen species, such as peroxides, play an aetiological role.
(3) It involves creativity, understanding of art form and the ability to improvise in the highly complex environment of a care setting.” David Cameron has boosted dementia awareness but more needs to be done Read more She warns: “To effect a cultural change in dementia care requires a change of thinking … this approach is complex and intricate, and can change cultural attitudes by regarding the arts as central to everyday life of the care home.” Another participant, Mary*, a former teacher who had been bedridden for a year, read plays with the reminiscence arts practitioner.
(4) Despite of the increasing diagnostic importance of the direct determination of the parathormone which is at first available only in special institutions in these cases methodical problems play a less important part than the still not infrequent appearing misunderstanding of the adequate basic disease.
(5) Mike Ashley told Lee Charnley that maybe he could talk with me last week but I said: ‘Listen, we cannot say too much so I think it’s better if we wait.’ The message Mike Ashley is sending is quite positive, but it was better to talk after we play Tottenham.” Benítez will ask Ashley for written assurances over his transfer budget, control of transfers and other spheres of club autonomy, but can also reassure the owner that the prospect of managing in the second tier holds few fears for him.
(6) Because many wnt genes are also expressed in the lung, we have examined whether the wnt family member wnt-2 (irp) plays a role in lung development.
(7) As prolongation of the action potential by TEA facilitates preferentially the hormone release evoked by low (ineffective) frequencies, it is suggested that a frequency-dependent broadening of action potentials which reportedly occurs on neurosecretory neurones may play an important role in the frequency-dependent facilitation of hormone release from the rat neurohypophysis.
(8) Michael Caine was his understudy for the 1959 play The Long and the Short and the Tall at the Royal Court Theatre.
(9) The presently available data allow us to draw the following conclusions: 1) G proteins play a mediatory role in the transmission of the signal(s) generated upon receptor occupancy that leads to the observed cytoskeletal changes.
(10) In concert with TF expressed by monocytes and macrophages this endothelial cell procoagulant activity may play a role in the pathogenesis of thrombotic disease.
(11) To determine whether or not the glycan moieties in hTPO play a role in the disease-associated epitopes in Hashimoto's thyroiditis, radiolabeled recombinant hTPO was immunoprecipitated after digestion with N-glycanase.
(12) Immunohistochemical observation of myoepithelial cells with monoclonal antibody from human mammalian cancer suggested that these cells play an important role in the process of glandular ducts formation.
(13) Anti-human factor V IgG decreased this enhanced thrombin formation in the presence of platelets, indicating that factor V from platelets was playing an important role in thrombin formation.
(14) The macrophage-derived product, interleukin 1 (IL 1) is thought to play an important regulatory role in the proliferation of T lymphocytes; however, its mechanism of action is unknown.
(15) The playing fields on which all those players began their journeys have been underfunded for years and are now facing a renewed crisis because of cuts to local authority budgets.
(16) The behaviour of DAO suggests that the enzyme plays an important role in the control of intracellular diamine concentration.
(17) It was with unanimous consent.” He denied that Trump’s tweets had played a part, saying: “No, no, no.
(18) When you have been out for a month you need to prepare properly before you come back.” Pellegrini will make his own assessment of Kompany’s fitness before deciding whether to play him in the Bournemouth game, which he is careful to stress may not be the foregone conclusion the league table might suggest.
(19) Photograph: Guardian The research also compiled data covered by a wider definition of tax haven, including onshore jurisdictions such as the US state of Delaware – accused by the Cayman islands of playing "faster and looser" even than offshore jurisdictions – and the Republic of Ireland, which has come under sustained pressure from other EU states to reform its own low-tax, light-tough, regulatory environment.
(20) Therefore, the measurement of the alpha-antitrypsin content plays the crucial part in differential diagnosis of primary (hereditary determined) and secondary (obstructive) emphysema.