(1) This is exemplified in lymphoma cells (chronic lymphocytic leukemia of B or T type, Sezary Syndrome, immunocytoma) that resemble mature and immunocompetent T and B cells, in T cell acute lymphoblastic leukemia (T-ALL) (equivalent to thymus cells) and in non-T ALL (corresponding to lymphoid progenitor cells in the bone marrow).
(2) Hepatitis B virus is used here to exemplify the application of recombinant DNA technology to the development of subunit vaccines and to illustrate their value in studies of other viral proteins with particular emphasis on the role of the core antigen in providing protection against viral infection and hence its potential in vaccine development.
(3) These results show for the first time the role of a specific pilus structure in colonization of the human intestine by V. cholerae O1 and exemplify the significance of a genetic regulon in pathogenesis.
(4) The method is exemplified by autoradiographs of human brain hemisphere ([ 3H]quinuclidinylbenzilate) and whole biceps muscle ([ 3H]alpha-bungarotoxin).
(5) It was thus found that the predictive efficacy of CASE was increased when it employed a combination of human and artificial intelligence, as exemplified by the CASE analysis of 'structural alerts.
(6) A comprehensive review of the world literature reveals that the systematic study of severe gender disorders--as exemplified by transsexualism--is relatively new, consisting of just over 25 years of collective experience.
(7) The disease exemplifies the validity of the Royal Veterinary College motto Venienti occurrite morbo (treat the disease at its first appearance).
(8) Further indications of the potential value of microbial metabolites are exemplified by the discovery and development of cyclosporin, to treat organ rejection, and mevinolin, a cholesterol-lowering drug.
(9) Salmonella contamination of swine and morbidity rates among the workers of swine-breeding complexes and the members of their families, as well as among the population inhabiting the zone of possible influence rendered by such complexes on the environment, have been studied as exemplified by 4 complexes for large-scale swine breeding, differing in their technology of swine raising and fattening, their systems of the purification and utilization of manure-containing sewage.
(10) Noradrenaline-beta-adrenoceptor-mediated neural plasticity in cat visual cortex exemplifies clearly established roles of the locus coeruleus system in brain function.
(11) It is argued that Western science reductionist approaches to the classification of "mass hysteria" treat it as an entity to be discovered transculturally, and in their self-fulfilling search for universals systematically exclude what does not fit within the autonomous parameters of its Western-biased culture model, exemplifying what Kleinman (1977) terms a "category fallacy."
(12) Instead we have injected vast sums of our own money to improve the playing squad and modernize LFC’s infrastructure-exemplified by the £120m advance from FSG to build the new Main Stand.
(13) The data exemplify the difficulty in reaching firm conclusions concerning associations with radiation exposure when the dependent variable exhibits a large degree of interindividual and day-of-assay variability.
(14) The paper deals with peculiarities of antioxidative activity of natural antioxidants (exemplified by ubiquinones) which permit their participation in the control of peroxidation intensity of membrane lipids.
(15) We therefore investigated the humoral and cell-mediated immune responses to mBSA in resistant mice (CBA) and susceptible mice (exemplified by C57BL) to determine whether these were associated with susceptibility to arthritis.
(16) Contamination by industrial chemicals such as polychlorinated biphenyls and polybrominated biphenyls; heavy metals such as lead, cadmium, and mercury; and pesticides such as dieldrin and chlordane exemplify the problem in feeds and the resulting problem of tissue residues in human foods.
(17) Several of these, exemplified by beta-bungarotoxin, show phospholipase A2 activity (phosphatide 2-acylhydrolase, EC 3.1.1.4) when tested in the presence of detergents.
(18) Three cases of blunt abdominal trauma are presented to exemplify the mechanism of trauma and the problems of diagnosis associated with any linear blow to the abdomen.
(19) incidence rate, absolute and relative increment of this value and the significance of a 1% increment as exemplified by this region.
(20) There are severe constraints that limit the combinations consistent with function, but the number of functionally consistent combinations observed exemplifies the plasticity of proteins.
Problem
Definition:
(n.) A question proposed for solution; a matter stated for examination or proof; hence, a matter difficult of solution or settlement; a doubtful case; a question involving doubt.
(n.) Anything which is required to be done; as, in geometry, to bisect a line, to draw a perpendicular; or, in algebra, to find an unknown quantity.
Example Sentences:
(1) The evidence suggests a multifactorial etiology for this problem.
(2) Technical factors that account for increased difficulty in these patients include: problems with guide catheter impaction and ostial trauma; inability to inflate the balloon with adequate guide catheter support; and need for increased intracoronary manipulation.
(3) Tests showed the cells survive and function normally in animals and reverse movement problems caused by Parkinson's in monkeys.
(4) IgE-mediated acute systemic reactions to penicillin continue to be an important clinical problem.
(5) Recent data collected by the Games Outcomes Project and shared on the website Gamasutra backs up the view that crunch compounds these problems rather than solving them.
(6) This is a fascinating possibility for solving the skin shortage problem especially in burn cases.
(7) The results of the evaluation confirm that most problems seen by first level medical personnel in developing countries are simple, repetitive, and treatable at home or by a paramedical worker with a few safe, essential drugs, thus avoiding unnecessary visits to a doctor.
(8) Hoursoglou thinks a shortage of skilled people with a good grounding in core subjects such as maths and science is a potential problem for all manufacturers.
(9) Despite of the increasing diagnostic importance of the direct determination of the parathormone which is at first available only in special institutions in these cases methodical problems play a less important part than the still not infrequent appearing misunderstanding of the adequate basic disease.
(10) Inadequate treatment, caused by a lack of drugs and poorly trained medical attendants, is also a major problem.
(11) Other articles in the series will look at particular legal problems in the dental specialties.
(12) The problem of treatment oneside malocclusions of adult patients needs to concern of anchorange.
(13) This exploratory survey of 100 patients with rheumatoid arthritis (RA) was conducted (1) to learn about the types and frequencies of disability law-related problems encountered as a result of having RA, and (2) to assess the respective relationships between the number of disability law-related problems reported and the patients' sociodemographic and RA disease characteristics.
(14) Psychiatry unlike philosophy (with its problem of solipsism) recognizes the existence of other minds from the nonverbal communication between doctor and patient.
(15) The evidence suggests that by the age of 15 years many adolescents show a reliable level of competence in metacognitive understanding of decision-making, creative problem-solving, correctness of choice, and commitment to a course of action.
(16) Many problems at the macroscopic level require clarification of how an animal uses a compartment of suite of muscles and whether morphological differences reflect functional ones.
(17) Fourteen representative cases of the problem are reported.
(18) In addition to the phase diagrams reported here for these two binary mixtures, a brief theoretical discussion is given of other possible phase diagrams that may be appropriate to other lipid mixtures with particular consideration given to the problem of crystalline phases of different structures and the possible occurrence of second-order phase transitions in these mixtures.
(19) This study examines the costs of screening patients for alcohol problems.
(20) Diphenoxylate-induced hypoxia was the major problem and was associated with slow or fast respirations, hypotonia or rigidity, cardiac arrest, and in 3 cases cerebral edema and death.