(1) This is exemplified in lymphoma cells (chronic lymphocytic leukemia of B or T type, Sezary Syndrome, immunocytoma) that resemble mature and immunocompetent T and B cells, in T cell acute lymphoblastic leukemia (T-ALL) (equivalent to thymus cells) and in non-T ALL (corresponding to lymphoid progenitor cells in the bone marrow).
(2) Hepatitis B virus is used here to exemplify the application of recombinant DNA technology to the development of subunit vaccines and to illustrate their value in studies of other viral proteins with particular emphasis on the role of the core antigen in providing protection against viral infection and hence its potential in vaccine development.
(3) These results show for the first time the role of a specific pilus structure in colonization of the human intestine by V. cholerae O1 and exemplify the significance of a genetic regulon in pathogenesis.
(4) The method is exemplified by autoradiographs of human brain hemisphere ([ 3H]quinuclidinylbenzilate) and whole biceps muscle ([ 3H]alpha-bungarotoxin).
(5) It was thus found that the predictive efficacy of CASE was increased when it employed a combination of human and artificial intelligence, as exemplified by the CASE analysis of 'structural alerts.
(6) A comprehensive review of the world literature reveals that the systematic study of severe gender disorders--as exemplified by transsexualism--is relatively new, consisting of just over 25 years of collective experience.
(7) The disease exemplifies the validity of the Royal Veterinary College motto Venienti occurrite morbo (treat the disease at its first appearance).
(8) Further indications of the potential value of microbial metabolites are exemplified by the discovery and development of cyclosporin, to treat organ rejection, and mevinolin, a cholesterol-lowering drug.
(9) Salmonella contamination of swine and morbidity rates among the workers of swine-breeding complexes and the members of their families, as well as among the population inhabiting the zone of possible influence rendered by such complexes on the environment, have been studied as exemplified by 4 complexes for large-scale swine breeding, differing in their technology of swine raising and fattening, their systems of the purification and utilization of manure-containing sewage.
(10) Noradrenaline-beta-adrenoceptor-mediated neural plasticity in cat visual cortex exemplifies clearly established roles of the locus coeruleus system in brain function.
(11) It is argued that Western science reductionist approaches to the classification of "mass hysteria" treat it as an entity to be discovered transculturally, and in their self-fulfilling search for universals systematically exclude what does not fit within the autonomous parameters of its Western-biased culture model, exemplifying what Kleinman (1977) terms a "category fallacy."
(12) Instead we have injected vast sums of our own money to improve the playing squad and modernize LFC’s infrastructure-exemplified by the £120m advance from FSG to build the new Main Stand.
(13) The data exemplify the difficulty in reaching firm conclusions concerning associations with radiation exposure when the dependent variable exhibits a large degree of interindividual and day-of-assay variability.
(14) The paper deals with peculiarities of antioxidative activity of natural antioxidants (exemplified by ubiquinones) which permit their participation in the control of peroxidation intensity of membrane lipids.
(15) We therefore investigated the humoral and cell-mediated immune responses to mBSA in resistant mice (CBA) and susceptible mice (exemplified by C57BL) to determine whether these were associated with susceptibility to arthritis.
(16) Contamination by industrial chemicals such as polychlorinated biphenyls and polybrominated biphenyls; heavy metals such as lead, cadmium, and mercury; and pesticides such as dieldrin and chlordane exemplify the problem in feeds and the resulting problem of tissue residues in human foods.
(17) Several of these, exemplified by beta-bungarotoxin, show phospholipase A2 activity (phosphatide 2-acylhydrolase, EC 3.1.1.4) when tested in the presence of detergents.
(18) Three cases of blunt abdominal trauma are presented to exemplify the mechanism of trauma and the problems of diagnosis associated with any linear blow to the abdomen.
(19) incidence rate, absolute and relative increment of this value and the significance of a 1% increment as exemplified by this region.
(20) There are severe constraints that limit the combinations consistent with function, but the number of functionally consistent combinations observed exemplifies the plasticity of proteins.
Topic
Definition:
(n.) One of the various general forms of argument employed in probable as distinguished from demonstrative reasoning, -- denominated by Aristotle to`poi (literally, places), as being the places or sources from which arguments may be derived, or to which they may be referred; also, a prepared form of argument, applicable to a great variety of cases, with a supply of which the ancient rhetoricians and orators provided themselves; a commonplace of argument or oratory.
(n.) A treatise on forms of argument; a system or scheme of forms or commonplaces of argument or oratory; as, the Topics of Aristotle.
(n.) An argument or reason.
(n.) The subject of any distinct portion of a discourse, or argument, or literary composition; also, the general or main subject of the whole; a matter treated of; a subject, as of conversation or of thought; a matter; a point; a head.
(n.) An external local application or remedy, as a plaster, a blister, etc.
(a.) Topical.
Example Sentences:
(1) Furthermore, all of the sera from seven other patients with shock reactions following the topical application of chlorhexidine preparation also showed high RAST counts.
(2) Topical and systemic antibiotic therapy is common in dermatology, yet it is hard to find a rationale for a particular route in some diseases.
(3) Community involvement is a key element of the Primary Health Care (PHC) approach, and thus an essential topic on a course for managers of Primary Health Care programmes.
(4) The discussion on topics like post-schooling and rehabilitation of motorists has intensified the contacts between advocates of traffic law and traffic psychologists in the last years.
(5) Eighty micrograms of the topically active parasympatholytic drug ipratropium were applied intranasally four times daily in 20 adults with perennial rhinitis and severe watery rhinorrhoea in a double-blind controlled cross-over trial.
(6) Health information dissemination is severely complicated by the widespread stigma associated with digestive topics, manifested in the American public's general discomfort in communicating with others about digestive health.
(7) Female CD-1 mice were initiated with 200 nmol 7,12-dimethylbenz[a] anthracene and topically promoted three times weekly for 20 weeks with doses of 25, 50, 100, or 200 nmol mirex.
(8) This study compares the effects of 60 minutes of ischemic arrest with profound topical hypothermia (10 dogs) on myocardial (1) blood flow and distribution (microspheres), (2) metabolism (oxygen and lactate), (3) water content (wet to dry weights), (4) compliance (intraventricular balloon), and (5) performance (isovolumetric function curves) with 180 minutes of cardiopulmonary bypass with the heart in the beating empty state (seven dogs).
(9) "This will obviously be a sensitive topic for the US administration, but partners in the transatlantic alliance must be clear on common rules of engagement in times of conflict if we are to retain any moral standing in the world," Verhofstadt said.
(10) The decision of the editors to solicit a review for the Medical Progress series of this journal devoted to current concepts of the renal handling of salt and water is sound in that this important topic in kidney physiology has recently been the object of a number of new, exciting and, in some instances, quite unexpected insights into the mechanisms governing sodium excretion.
(11) The tetracaine component of TAC is superfluous for obtaining topical anesthesia of minor dermal lacerations of the face in children.
(12) I think we are still trying to understand all that and I think that fits under the broader topic of social licence and what bringing in automation to an area does to that region as a whole, which we don’t quite know yet.” Could carbon farming be the answer for a 'clapped-out' Australia?
(13) UPDATE II [Tues.] Two other items that may be of interest: first, Guardian editor-in-chief Alan Rusbridger was the guest for the full hour yesterday on Democracy Now, discussing the paper's role in reporting the NSA stories, and the video and transcript of the interview are here ; second, marking our collaboration on a series of articles about spying on Indians, the Hindu has a long interview with me on a variety of related topics, here .
(14) CNS excitation and seizures, manifestations of organochlorine intoxication, can occur following ingestion or inappropriate application of the 1 per cent topical formulation of lindane used to treat scabies and lice.
(15) A water based 5% benzoyl peroxide gel (Benzac W5) was compared with topical 1% clindamycin phosphate solution (Cleocin T) in the treatment of acne vulgaris using a randomized, investigator blind study design.
(16) In conclusion, this study indicates that topical CsA is capable of locally suppressing a strong T-cell-mediated immune response after an initial short-term systemic dose of CsA.
(17) Poly(ortho ester) bioerodible polymers are suitable materials for the topical administration of a wide variety of therapeutic agents; varying the nature and amounts of excipients physically incorporated into the polymer will vary the erosion rates from a few hours to many months.
(18) Future studies will need to carefully evaluate the vehicle used and the strength of topical CsA employed.
(19) The animal model of psoriasis was effectively treated by bimolane, both systemically and topically, and also by parenteral methotrexate and topical betamethasone valerate.
(20) Data were compared with those from a previous study with topical 1% minoxidil solution.