(n.) The act of exploring, penetrating, or ranging over for purposes of discovery, especially of geographical discovery; examination; as, the exploration of unknown countries
(n.) physical examination.
Example Sentences:
(1) But earlier this year the Unesco world heritage committee called for the cancellation of all such Virunga oil permits and appealed to two concession holders, Total and Soco International, not to undertake exploration in world heritage sites.
(2) To explore an early step, we synthesized 5 beta-cholest-7-ene-3 beta,6 alpha,14 alpha-triol in tritiated form.
(3) A review is presented concerning the development of new neuroimaging techniques in the last decade which have improved the diagnostic exploration of patients with spinal cord injuries, including studies of possible sequelae.
(4) Tottenham Hotspur’s £400m redevelopment of White Hart Lane could include a retractable grass pitch as the club explores the possibility of hosting a new NFL franchise.
(5) United believe it is more likely the right-back can be bought in the summer but are exploring what would represent the considerable coup of acquiring the 26-year-old immediately.
(6) Further exploration of these excretory pathways will provide interesting new insights on the numerous cholestatic and hyperbilirubinemic syndromes that occur in nature.
(7) The relationship of weight history with current fat distribution was also explored.
(8) In a new venture, BDJ Study Tours will offer a separate itinerary for partners on the Study Safari so whilst the business of dentistry gets under way they can explore additional sights in this fascinating country.
(9) Recognition of this deficiency in our knowledge spurred a belated explosion of research that began with an exploration of the fine structure of the mesothelium.
(10) In our efforts to explore alternative treatment regimens for multidrug-resistant tumors we have examined the sensitivity of MDR tumor cell lines to lymphokine activated killer (LAK) cells.
(11) Dacryography is the only means of exploring the permeability of the lacrymal ducts and to conclude as the whether watering of the eyes is organic or functional.
(12) Intraperitoneal drain should therefore be used when choledochus has been explored.
(13) Individual play techniques are explored, and two case histories are given as examples of how the occupational therapist works with the child, the family, and other practitioners.
(14) The present study explored the possibility that SOD-mimics such as desferrioxamine-Mn(III) chelate [DF-Mn] or cyclic nitroxide stable free radicals could protect from O2-.-independent damage.
(15) The remaining 16 patients were explored for persistent symptoms, an abnormality on GI series, or a mass lesion on CT scan.
(16) The current study explored the temporal course of the perception of vowel duration.
(17) All 15 patients survived, and exploration of the cannulation site for bleeding was required in three patients.
(18) Forty five elderly patients undergoing total hip replacements were assessed one day before and two days after surgery in order to explore the relationship between pre-operative anxiety and post-operative delirium.
(19) The aim of the present study was to explore the possible role of heat shock proteins in the manifestation of this heat resistance.
(20) In the present study, the role of antiperipheral nerve myelin antibody (anti-PNM Ab) in demyelination by generating the terminal attack complex (C5b-9) of complement was explored in patients with Guillain-Barré syndrome (GBS) and other demyelinating neuropathies.
Upstream
Definition:
(adv.) Toward the higher part of a stream; against the current.
Example Sentences:
(1) The latter result indicates that the dexamethasone block is upstream from release of esterified arachidonic acid.
(2) Other DNase I hypersensitive sites located adjacent to the S14 cap site at -65 to -265 base pairs (Hss-1) or upstream at -1.3 kb (Hss-2), -2.1 kb (Hss-3'), -5.3 kb (Hss-4), and -6.2 kb (Hss-5) remained unaffected by changes in S14 gene transcription.
(3) No other essential regulatory sequence is located further upstream.
(4) Analysis of glutamate dehydrogenase (GDH) expression by enzyme assay and immunoblots, as well as Northern and dot blots of poly (A)+ RNA, in the deletion strains indicates that there are two upstream regulatory sequences that control the level of gene expression.
(5) Although the islet promoter was found to lack a TATA box, a major transcript from the islet promoter was mapped 486 nucleotides upstream of the translation initiation site.
(6) If this is the only issue, flight would be fine, but need to make sure that it isn’t symptomatic of a more significant upstream root cause.” Elon Musk (@elonmusk) Btw, 99% likely to be fine (closed loop TVC wd overcome error), but that 1% chance isn't worth rolling the dice.
(7) There was an upstream "HTF" island (Hpa II tiny fragments) followed by four direct repeats of the "chorion box" enhancer.
(8) Six discrete 'phased' nucleosomes are present upstream from the gene and are modulated by induction.
(9) That the opposite was observed in our study indicates that the increase in Pst(L), which results from parenchymal hysteresis, offsets any dimensional decrease in upstream airways due to airways hysteresis.
(10) The human gene-specific upstream stimulatory transcription factor (USF) is required, both in vivo and in vitro, for maximal expression of the major late promoter (MLP) of adenovirus.
(11) A single upstream CCAAT element is essential for high level expression in both liver and non-liver cells.
(12) Deletional analysis demonstrated that a region between -86 and -70 nucleotides upstream from the transcriptional origin of the human VIP gene was responsible for stimulation by forskolin.
(13) The gradient of increasing copper and zinc concentrations with increasing distance upstream from the mouth of the estuary reported in 1975 could not be statistically validated.
(14) By using primer 1 (5'-AAAGAATTCATGGAATCCAGGATCTG-3', upstream nucleotides 157 to 2877), primer 2 (5'-AAAGAATTCATGAACGTGAAGGAATCG-3', upstream nucleotides 1846 to 2877), and primer 4(5'-ATAAAGCTTAATCAGACGTTCTCTTCTTC-3', downstream nucleotides 157 to 2877 and 1846 to 2877), the HCMV B gene code region sequence and its glycoprotein 52 kd antigenic domain sequence were amplified from the recombinant plasmid pBH1 DNA containing the HCMV B gene.
(15) The sequence TAGAAAA was found 30 bases upstream from the transcription initiation site and could be analogous to the TATA box.
(16) A potential ribosome binding site was located 20 nucleotides upstream of the initiation codon in the 5' noncoding region.
(17) A 1,300-base pair fragment of 5'-flanking sequence containing these elements, ligated upstream from a firefly luciferase reporter gene and transfected into cultured normal rat kidney cells, demonstrated strong promoter activity.
(18) Since these three mutants differ in the extent to which EBNA expression is impaired, the data suggest that there are several critical regions upstream of the open reading frame that regulate EBNA expression in COS-1 cells.
(19) One class II mutant carried a Tn10 insertion in or close to malT whereas in the remaining class II mutants the insertions were located at least 4 kb upstream of pulA in a region which may define a new regulatory locus of the maltose operon.
(20) We report here that a nuclear protein is tightly bound to the HBV genome at a position approximately 190 bases upstream from the S gene promoter.