What's the difference between expression and misexpression?
Expression
Definition:
(n.) The act of expressing; the act of forcing out by pressure; as, the expression of juices or oils; also, of extorting or eliciting; as, a forcible expression of truth.
(n.) The act of declaring or signifying; declaration; utterance; as, an expression of the public will.
(n.) Lively or vivid representation of meaning, sentiment, or feeling, etc.; significant and impressive indication, whether by language, appearance, or gesture; that manner or style which gives life and suggestive force to ideas and sentiments; as, he reads with expression; her performance on the piano has expression.
(n.) That which is expressed by a countenance, a posture, a work of art, etc.; look, as indicative of thought or feeling.
(n.) A form of words in which an idea or sentiment is conveyed; a mode of speech; a phrase; as, a common expression; an odd expression.
(n.) The representation of any quantity by its appropriate characters or signs.
Example Sentences:
(1) Here we have asked whether protection from blood-borne antigens afforded by the blood-brain barrier is related to the lack of MHC expression.
(2) Similar experimental manipulation has yielded in vitro lines established from avian B-cell lymphomas expressing elevated levels of c-myc or v-rel.
(3) When micF was cloned into a high-copy-number plasmid it repressed ompF gene expression, whereas when cloned into a low-copy-number plasmid it did not.
(4) We also show that proliferation of primary amnion cells is not dependent on a high c-fos expression, suggesting that the function of c-fos is more likely to be associated with other cellular functions in the differentiated amnion cell.
(5) Injection of resistant mice with Salmonella typhimurium did not result in the induction of a population of macrophages that expressed I-A continuously.
(6) Stimulation is also observed with mixtures of APC expressing DPw3 and APC expressing A1, and likewise, DPw3+ APC become stimulatory when preincubated with supernatants from A1-positive cells.
(7) BL6 mouse melanoma cells lack detectable H-2Kb and had low levels of expression of H-2Db Ag.
(8) These studies show that metabolic activation is necessary for the expression of the mutagenic activity of aflatoxins B1 and G1 in N. crassa.
(9) We also show that the gene of the main capsid protein is expressed from its own promoter in an Escherichia coli strain.
(10) Using the oocyte system to express size-fractionated mRNA, we have also determined that the mRNA coding for this protein is between 1.9-2.4 kilobases in length.
(11) Because many wnt genes are also expressed in the lung, we have examined whether the wnt family member wnt-2 (irp) plays a role in lung development.
(12) A beta-adrenergic receptor cDNA cloned into a eukaryotic expression vector reliably induces high levels of beta-adrenergic receptor expression in 2-12% of COS cell colonies transfected with this plasmid after experimental conditions are optimized.
(13) Four other independent LCMV-GP2(275-289) specific H-2Db-restricted CTL clones also expressed V alpha 4 and V beta 10 gene elements.
(14) Maximal yields of lipid and aflatoxin were obtained with 30% glucose, whereas mold growth, expressed as dry weight, was maximal when the medium contained 10% glucose.
(15) Recent studies have shown that an aberration in platelet-derived growth factor gene expression is unlikely to be a factor in proliferation of smooth-muscle cells.
(16) Thus, human bronchial epithelial cells can express the IL-8 gene, with expression in response to the inflammatory mediator TNF regulated mainly at the transcriptional level, and with elements within the 5'-flanking region of the gene that are directly or indirectly modulated by the TNF signal.
(17) In concert with TF expressed by monocytes and macrophages this endothelial cell procoagulant activity may play a role in the pathogenesis of thrombotic disease.
(18) The possibility that both IL 2 production and IL 2R expression are autonomously activated early in T cell development, before acquisition of the CD3-TcR complex, led us to study the implication of alternative pathways of activation at this ontogenic stage.
(19) A domain containing a CA repeat, similar to ones found in other late, cAMP-induced Dictyostelium genes, is required for cAMP-induced and developmental expression.
(20) This study examines the role of sex hormones in modulating the expression of autoimmunity in NZB x NZW F1 mice.
Misexpression
Definition:
(n.) Wrong expression.
Example Sentences:
(1) The resulting Hox-2.2 misexpression produces early postnatal lethality as well as craniofacial and axial skeletal perturbations that include open eyes at birth, cleft palate, micrognathia, microtia, skull bone deficiencies, and structural and positional alterations in the vertebral column.
(2) We have confirmed this model by showing that misexpression of the achaete-scute T4 gene induces ectopic Sxl expression and male-specific lethality, confirming that achaete-scute T4 is the sisterless-b counting element.
(3) Lack of ap function results in loss of ap-expressing muscles, while misexpression of ap using a heterologous promoter produces ectopic muscles.
(4) As revealed by dosage-dependent dominant interactions, males die with too high a ratio of sc+ to dpn+, caused by misexpression of Sex lethal (Sxl) in embryos, and females die with too low a ratio of sc+ to dpn+, because of altered embryonic Sxl expression.
(5) We have used transgenic animals misexpressing different rhodopsins in the major class of photoreceptor cells to demonstrate that ninaA is required for normal function by two homologous rhodopsins, but not by a less conserved member of the Drosophila rhodopsin gene family.
(6) A minority of these cells with an activated oncogene(s) (or one of the descendant cells) may also come to misexpress a stability gene(s).
(7) Data are described which suggest that the causes of misexpression in the preputial gland and testis are different.
(8) Developmental alterations due to a variant expression pattern would point to the function of the misexpressed gene.
(9) Some of the malformations observed in Hox-2.3 gain-of-function mutants overlap with those seen in Hox-1.1 and Hox-2.2 misexpression mutants which suggests functional similarities between paralogous homeobox genes.
(10) A normal cell that misexpresses only a stability gene(s) may form an evolving and genetically unstable cell line that may later misexpress an oncogene(s).
(11) The majority of cells that misexpress an oncogene(s) and that later form a tumor probably form nonevolving benign tumors.
(12) A cell or cell line that misexpresses both an oncogene(s) and a stability gene(s) may form a genetically unstable tumor that creates diverse variants, allowing for extensive tumor cell evolution and the acquisition of malignant and metastatic properties.
(13) We have identified a cold-sensitive allele, l(3)S12(3), and characterized conditional misexpression of the gene associated with this mutation as well as with several euchromatic insertions of l(3)S12+ transposons.
(14) Analysis of these embryos shows that high levels of N-CAM misexpression do not effect neural tube formation even though ectopic expression of N-CAM in epidermis and somitic mesoderm caused specific defects in the structure of these tissues.
(15) The photoreceptor cells in which this opsin was misexpressed showed new spectral characteristics and physiology.
(16) Furthermore, gross defects in the larval cuticle resulting from misexpression of the 69-kDa protein suggest that this protein performs additional functions in the early embryo.
(17) Thus, targeted misexpression of this tissue-specific regulator during mammalian embryogenesis can activate, either directly or indirectly, a diverse set of genes normally restricted to a different cell lineage and a different cellular environment.