(v. t.) To quench; to put out, as a light or fire; to stifle; to cause to die out; to put an end to; to destroy; as, to extinguish a flame, or life, or love, or hope, a pretense or a right.
(v. t.) To obscure; to eclipse, as by superior splendor.
Example Sentences:
(1) Some 10 fire engines remained on the scene after rushing there to extinguish the many blazes caused by the crash.
(2) Perhaps strangely, it was the second remark that troubled me more than the possibility that humanity would be extinguished by my hand.
(3) A specific interaction of conformationally intact rhinovirus with peripheral blood mononuclear leukocytes was required for induction of the response, since the response was extinguished at reduced quantities of infectious rhinovirus, and acid inactivated rhinovirus did not augment cellular cytotoxicity.
(4) When tone presentations were continued, without further pairing with morphine, the hyperthermic response to the tone was gradually extinguished.
(5) Leukocyte suspensions from the infected agammaglobulinemic patient extinguished detectable infectious virus in vitro.
(6) Transcription of MyoD itself is extinguished in butyrate-treated myoblasts and myotubes, an effect that may be due to the inability of MyoD to autoactivate its own transcription.
(7) Fasting for 24 h extinguished the greatest part of this response.
(8) Abbado sees this as meaning that music is both destroyed and redeemed by its temporality: it exists and is extinguished in a moment, but has the endless possibility of being created anew in time.
(9) A case history is presented in which progressive muscle relaxation, diaphragmatic breathing, and flooding were used to extinguish and countercondition a writing phobia in a junior-year occupational therapy student.
(10) When, in stoppage time, the 33-year-old striker swept a first-time shot home any lingering Villa optimism was extinguished.
(11) Rats implanted with placebo pellets and given access to morphine reestablished lever pressing, while those given access to isotonic saline extinguished their lever pressing.
(12) A relationship seems to exist between the tumor load and the immune status, which reverts to a normal pattern when the former is extinguished.
(13) Furthermore, TSE1-repressed genes were hormone inducible, whereas fully extinguished genes were not.
(14) But then a mismanaged clean-up in an underground garbage dump ignited a seam of anthracite eight miles long that proved impossible to extinguish.
(15) The fire extinguisher was thrown after protesters swarmed into Millbank Tower, the Westminster building that houses the Conservative party's headquarters.
(16) Functional smoke detectors and fire extinguishers were present in 75% and 27% of homes, respectively.
(17) This level of flash did not extinguish the response to the stimulus.
(18) In London a candlelit vigil – which the government hopes will be emulated in churches, by other faiths and by families across the land – will be held at Westminster Abbey, ending with the last candle being extinguished at 11pm, the moment war was declared.
(19) We review five specific techniques for the production of these antibodies (Abs): (a) So-called "shotgun," non-selective approach; (b) cascade procedure; (c) lymphocyte "panning"; (d) cyclophosphamide elimination of unwanted Ab producers; and finally (e) use of polyclonal antisera to extinguish unwanted antibody production.
(20) All peaks of the pyr-MEP were extinguished in the animals subjected to impact forces of 50 g-cm and above (n = 12).
Kindle
Definition:
(v. t. & i.) To bring forth young.
(v. t.) To set on fire; to cause to burn with flame; to ignite; to cause to begin burning; to start; to light; as, to kindle a match, or shavings.
(v. t.) Fig.: To inflame, as the passions; to rouse; to provoke; to excite to action; to heat; to fire; to animate; to incite; as, to kindle anger or wrath; to kindle the flame of love, or love into a flame.
(v. i.) To take fire; to begin to burn with flame; to start as a flame.
(v. i.) Fig.: To begin to be excited; to grow warm or animated; to be roused or exasperated.
Example Sentences:
(1) The anticonvulsant properties of the endogenous excitatory amino acid antagonist, kynurenic acid (KYA), were studied in prepubescent and adult rats using the amygdaloid kindling model of epilepsy.
(2) For the purpose of contributing methodologically to experimental research on epilepsy, we investigated whether a difference exists in kindling development between acute and chronic preparations using identical species of animals, kindled brain tissues, stimulus intervals, and intensities.
(3) The kainate and quisqualate types of excitatory amino acid receptor were visualized autoradiographically in brain sections from rats kindled by stimulating the angular bundle.
(4) A corrective effect of Nicotinamide on oxidation processes in ganglion and neuroglial cells of cerebral cortex sensorimotor zone in "kindling" phenomenon was studied in the experiments on mice of C57BL line.
(5) PHT, CBZ, VPA, and CZP, SK&F 89976-A and SK&F 100330-A inhibited seizures in corneally kindled rats.
(6) The inhibitory effect of serotonin on the kindling model of epilepsy was investigated in the adult rat.
(7) In the second experiment, 15- and 30-day-old rats underwent unilateral carotid ligation followed by kindling in the ipsilateral amygdala.
(8) If Obama is your new iPad, Sarah Palin is your old Kindle.
(9) Electrical amygdaloid kindling was carried out with a 15 min inter-stimulus interval (ISI) in a control situation with intravenous (i.v.)
(10) We suggest that the NE-dependent mechanism responsible for the seizure suppression observed to follow concurrent, alternate stimulation and the suppression of seizure development using single-site kindling paradigms may be the same.
(11) GABAergic neurons and terminals are also increased in the hippocampus of seizure-sensitive gerbils, and kindling of the hippocampus and amygdala appears to enhance GABAergic inhibitory mechanisms.
(12) Based on an hypothesis that links electrical kindling in the limbic system (leading to seizures) to reverse tolerance or sensitivity to cocaine's effects, carbamazepine is being tested as a treatment for human cocaine users.
(13) reversed the increase in locomotion and elevation of multiple squeak thresholds in the bilaterally kindled rats.
(14) In fully kindled animals a stimulus-induced generalized seizure gave rise to a three-fold increase of noradrenaline levels in the stimulated hippocampus as compared to baseline levels (15-min samples).
(15) In the present work no significant differences were found between the behaviour of FG7142-kindled rats and vehicle-treated controls in social interaction test, elevated plus maze, or the Vogel conflict test of anxiety or in tests of home cage aggression or startle responses.
(16) Amygdaloid kindling of rats produced an increase in hippocampal Met5-enkephalin-Arg6-Gly7-Leu8 and cholecystokinin immunoreactivities and simultaneously a decrease in dynorphin A1-8 content.
(17) The data suggest that GABA-T inhibitors, such as vigabatrin, differ from most antiepileptic drugs previously tested in the kindling model in that they may produce both anticonvulsant and proconvulsant effects at the same dose in the same animal as a function of time after administration.
(18) However, the concentration of Asp decreased depending on the kindling stage, reaching the lowest value of 33% in comparison with the normal value.
(19) Thus, electrophysiological alterations within the first synaptic relay of the hippocampal trisynaptic circuit, the dentate gyrus, cannot explain the long duration of the kindling effect.
(20) In brightness discrimination reaction (BDR) the learning performance of PTZ-kindled animals was not influenced.