(n.) A nesting or unfledged bird; in falconry, a young hawk from the nest, not able to prey for itself.
(a.) Unfledged, or newly fledged.
Example Sentences:
(1) This was supported by the fact that Poly EYK(EYA)5 is alpha-helical but the peptides used here showed only a slight propensity to adopt this structure and it did not correlate with their functional activity.
(2) To understand the molecular basis of epitope selection we have analysed the hierarchy of T cell epitopes in a repeating synthetic polypeptide antigen Poly 18, Poly EYK(EYA)5 in the mice of H-2d haplotype.
(3) Animals which are nonresponders to Poly EYA or Poly EFA, when primed with Poly EYAEFA, produce both T cells and antibodies which crossreact with Poly EYA and Poly EFA.
(4) However, we observed the dominance of (EYA)5 reactive clones even when EYK(EYA)3 was used as an immunogen and this could be related to the degeneracy of their antigen specificity.
(5) We investigated the Ia and T cell receptor interaction sites on the synthetic polypeptide antigen poly-18 [poly-EYK(EYA)5] using T cell hybridoma clones specific for this antigen in the context of I-Ad.
(6) We have analyzed the fine specificity of 21 randomly chosen Poly 18-reactive, (EYA)5-specific and H-2d-restricted T cell hybridomas derived from H-2d, H-2bxd, and H-2b----H-2bxd Poly 18-responding mice to determine the number of unique antigen reactivity patterns represented by this T cell population.
(7) In these mice Poly 18 induced good T-cell proliferative response, which was inhibited by anti-Ia antibody, and the mice were able to respond to tyrosine-containing polypeptide Poly EYA but not to the phenylalanine-containing antigen Poly EFA.
(8) Synthetic antigen Poly EYK(EYA)5 induces T cells of narrowly defined fine specificity as represented by the two I-Ad-restricted T cell hybridomas, A.1.1 and B.1.1.
(9) Mice of H-2b,d haplotypes are high responders to Poly EYA, mice of H-2p,q haplotypes are high responders to Poly EFA and mice of H-2b,d,p,q strains are high responders to Poly EYAEFA.
(10) The binding of (EYA)5 to the antigen-binding groove of I-Ad appears to generate a highly diversified T cell response.
(11) (EYA)5 reactive T cell clones appear to be very heterogenous and much larger in number than EYK(EYA)4 reactive clones.
(12) Hybridoma A.1.1 responds to EYK(EYA)4 as the minimum antigenic sequence while hybridoma B.1.1 recognizes (EYA)5 sequence.
(13) By considering, in particular, the kinetic constants obtained with the pentapeptides AAYAA, EEYAA, AEYAA, EAYAA, with the tetrapeptides AYAA and EYAA and with the tripeptides AYA and EYA, it turns out that N-terminal acidic residue(s) are only essential with TPK-IIB for efficient phosphorylation with multiple residues displaying a synergistic effect.
(14) The unusual hierarchy observed for immunodominance in these overlapping epitopes of EYK(EYA)5 sequence suggest a bias in the selection of T cell repertoire based upon the crossreactivity between potential epitopes generated as a result of antigen processing.
(15) The T cell response directed to the repeating tripeptide epitope (EYA)5 is extremely heterogenous even though the epitope has a relatively simple amino acid sequence.
(16) Therefore, (EYA)5-I-Ad complex allows the activation of unrelated T cell clonotypes with the same overall antigen specificity and MHC restriction, but with distinct microheterogeneity in response and receptor usage.
(17) The epitope (EYA)3EYK appears to be subdominant since it can elicit Poly EYK(EYA)5 specific T cells upon immunization but does not appear to be part of Poly EYK(EYA)5 repertoire.
(18) (EYA)5 reactive clones could be elicited by at least three short Poly-18 derived epitopes (EYA)4, EYK(EYA)3 and (EYA)3EYK while EYK(EYA)4 reactive clones elicited only by the EYK(EYA)3 epitope.
(19) Surprisingly, the substituted peptide EYAEAA(EYA)3 could activate A.1.1, indicating that an Ala at position 5 instead of a Tyr obviates the critical requirement for Lys3.
(20) Hen egg lysozyme, pigeon cytochrome C and the synthetic polypeptide Poly 18, Poly EYK(EYA)5 antigen produce good antibody responses.
Falcon
Definition:
(n.) One of a family (Falconidae) of raptorial birds, characterized by a short, hooked beak, strong claws, and powerful flight.
(n.) Any species of the genus Falco, distinguished by having a toothlike lobe on the upper mandible; especially, one of this genus trained to the pursuit of other birds, or game.
(n.) An ancient form of cannon.
Example Sentences:
(1) 8.51pm GMT Falcons 27 - Seahawks 21, 3:35 4th of quarter The smash mouth Falcons are back on first down, Turner has 12 more yards.
(2) But, as Falconer admits, the chance of this bill passing all its stages in the Lords and the Commons before the election are slender as it requires the government to give it time.
(3) Although private capital was gradually replaced by public investment, the latter was much less productive as criminal organisations distort and corrupt the public procurement process.” Facebook Twitter Pinterest The Italian anti-mafia prosecutor, Giovanni Falcone.
(4) These formulae apply for arbitrary phenotypic distributions, yet even with multivariate Gaussian distributions of phenotypic effects the formula for correlated selection includes a correction to the standard formula in Falconer (1989).
(5) Photograph: Associated Press According to the Italian judge Giovanni Falcone, who led the “Maxi Trial” against the Sicilian Mafia in 1987 and was assassinated by the organisation, “more than one-fifth of Mafia profits come from public investment”.
(6) Updated at 7.28pm GMT 7.26pm GMT Falcons 20 - Seahawks 0, 0:25 2nd quarter Golden Tate has it in the slot for four yards and a first down.
(7) Labour peer Lord Falconer proposed a bill stating that if someone has a prognosis of less than six months to live, they should be allowed to have an assisted death subject to a number of safeguards and checks.
(8) 6.46pm GMT Falcons 10 - Seahawks 0, 0:31 1st quarter On 3rd down, Wilson can't find Golden Tate on the far sideline and Seattle punt it down to the Atlanta 13.
(9) The former Atlanta Falcons quarterback is expected to be released from federal custody on 20 July but will be on probation for three years.
(10) On Friday, an unmanned SpaceX Falcon rocket is set to take off from Cape Canaveral for the International Space Station orbiting Earth.
(11) Facebook Twitter Pinterest SpaceX Falcon 9 rocket successfully lands on ocean platform The busts Those accomplishments have not come without repeated failures, the most spectacular of which occurred during attempts to land their Falcon 9 rockets, named after Star Wars’ Millennium Falcon .
(12) An alternative model due to Falconer (1965) is also fitted.
(13) How did Hilary Benn, Maria Eagle, Charles Falconer and Paul Kenny choose Trident as the totem of revolt?
(14) Stereoscopic depth perception is demonstrated in the falcon, a non-mammalian with binocular vision.
(15) So where is the left-lurching that the Tories allege, with Charles Falconer, Tristram Hunt and Douglas Alexander all exalted?
(16) Grating acuity, the ability to resolve high-contrast square-wave gratings, was measured in a falcon and in humans under comparable conditions.
(17) On the Colville River in northwestern Alaska, the last young falcons will fledge in 1975 and the remaining adult population will disappear by 1980 unless the present rate of reproductive failure is drastically and quickly reversed.
(18) The flat acuity-luminance function of the falcon results from adaptations which increase the optical sensitivity of the eye compared with the globose eye of strongly diurnal falconiformes.
(19) Given, for example, that over half of them have identified as devout, it is hard to imagine what would have persuaded the 11 peers behind an anti-Falconer paper, An Analysis of the Assisted Dying Bill , to look kindly upon its provisions, but the document constructs an ostensibly faith-free, "clear-thinking" case against, which is nonetheless replete with routine frighteners and selective misrepresentation.
(20) I remember most vividly, as the prey was seized, how one lazuline wing fell outwards like a flag; the hobby's wings seemed to chop and paddle and there was this momentary drama-less inelegance to it, then the falcon swept the victim back into the peerless symmetry of its going, and all was done.