(1) Structure assignment of the isomeric immonium ions 5 and 6, generated via FAB from N-isobutyl glycine and N-methyl valine, can be achieved by their collision induced dissociation characteristics.
(2) Polyribosomes isolated from the livers of rats sacrificed 6 h after treatment with actinomycin D showed a 42% reduction in their capacity to bind anti-RSA Fab'.
(3) The combined amounts of S-1 and Fab binding to actin suggested that the activation of the myosin ATPase activity was due to actin free of Fab.
(4) Brief digestion at neutral pH without reduction produced a molecule in which the Fab and Fc fragments were still linked by a pair of labile disulphide bridges, and the Fc fragment released by cleaving these bonds, called 1Fc fragment, contained a portion of the ;hinge' region including an interchain disulphide bridge.
(5) Initial analysis of aspirated bone marrow disclosed ALL FAB-L1 morphology, common (Ia+, cALLa+) immunophenotype and a complex abnormal karyotype.
(6) An isotopic double-labeling technique was developed that demonstrated that the 603 crystals bind 1 mol of hapten per mol of Fab-fragment, but with a binding constant significantly lower than that observed in solution.
(7) Its autoimmune nature is probable although we failed to demonstrate any inhibitory effect of Fab obtained from the patient's purified IgM.
(8) The use of Fab fragments in conjunction with Fab-specific secondary and tertiary antisera improved tissue penetration and made it possible to identify a number of the immunoreactive neurons.
(9) We present here a case of acute monocytic leukemia (AMoL, FAB M5b) with four copies of chromosome #8.
(10) The superprecipitation activity of Fab-myosin was also highly dependent on phosphorylation of the light chains.
(11) The FAB-MS was used in conjunction with carboxypeptidase Y digestion and results indicated that this procedure proved to be a powerful tool for rapid sequence determination.
(12) Fab fragment half times were only 0.31 and 5.4 h, with 9% remaining intravascularly.
(13) In 100 children with acute lymphatic leukaemia the cytomorphological subclassification of the pathological cell type was made according to Mathé and the French-American-British Co-operative group (FAB).
(14) The affinity-purified rabbit anti-human chorionic gonadotropin Fab'-beta-D-galactosidase conjugate was separated from non-specific goat Fab'-beta-D-galactosidase conjugate and unconjugated beta-D-galactosidase by affinity chromatography on a column of goat (anti-rabbit IgG) IgG-Sepharose 4B using 4 M urea.
(15) At 37 degrees C, heparin-releasable binding of LDL and binding of Fab fragments were double that at 4 degrees C, whereas binding of antibody remained unchanged.
(16) An infertile 37-year-old woman was diagnosed as having acute monocytic leukemia (AMoL) (FAB classification; M5b).
(17) 5-10%), according to analysis by high-performance liquid chromatography (HPLC) and fast atom bombardment mass spectrometry (FAB-MS).
(18) The Fab fragments contained neutral, monosialylated, and disialylated oligosaccharides, whereas the Fc fragment contained only neutral and monosialylated structures.
(19) IgM antibody levels against both whole IgA and Fab of IgA were significantly higher than IgG antibody levels.
(20) CD11b was uniformly weakly expressed by all FAB subgroups.
Fac
Definition:
(n.) A large ornamental letter used, esp. by the early printers, at the commencement of the chapters and other divisions of a book.
Example Sentences:
(1) Speaking after the meeting in the Air Studios in north London, FAC board member and Radiohead guitarist Ed O'Brien described the outcome as "groundbreaking".
(2) Comparison of the results of this study with previously reported programs of FAC chemotherapy in patients with metastatic breast cancer shows that this study achieved higher overall and complete response rates.
(3) The following measurements were made relative to lymph nodes of untreated animals: (i) the expansion of the T-cell dependent areas in combination with the increase of HEV in this area, as detected by the HEV-specific mAb MECA-325, using morphometric analysis: (ii) the influx of FITC-labelled lymphocytes from the blood into the lymph node by FACS: (iii) the capacity of HEV to bind lymphocytes using an in vitro binding assay.
(4) FACS analysis revealed that approximately 40% of the EC population expressed HLA-DR antigen.
(5) At the functional level, we show that polyreactive IgM autoantibodies are produced by FACS-sorted CD5high B cells, but not by CD5- B cells from adolescent spleen.
(6) We studied changes in the distribution pattern of relative RNA content during the in vitro aging of TIG-3 cells by flow cytometry (FACS III).
(7) A regimen of ip injected antibody achieved rapid reduction of NK cells in diabetic and nondiabetic BB rats by FACS analysis.
(8) Pretreatment of beta-cells, purified by FACS with IL-1 beta results in a 40% inhibition of glucose-stimulated insulin secretion that is prevented by the nitric oxide synthase inhibitor, NG-monomethyl-L-arginine (NMMA).
(9) To test the diagnostic utility of FACs in BAL fluids, we compared 20 PCP-positive and 28 PCP-negative fluids as assessed by silver stains.
(10) The systematic study highlighted the fact that any laboratory contemplating conversion from microscopic reading of the GIFT should carefully evaluate and standardize their interpretation of FACS results with their manual reference method.
(11) We describe here the methods by which enriched populations of oligodendrocytes were isolated from adult porcine brains using Percoll density gradient centrifugation and their immunological properties analyzed by a fluorescence-activated cell sorter (FACS).
(12) For those who do not respond to FAC, the combinations active in refractory disease include vinca alkaloids and mitomycin C combinations.
(13) An additional 117 patients with similar characteristics were treated with the same program with the addition of bacillus Calmette-Guérin (BCG) by scarification (FAC-BCG-LMS).
(14) FACS-negative cell fractions were treated with heparitinase, nitrous acid, methanol-chloroform, or EDTA without modifying the number of reacting cells.
(15) FACS sorted Leu-7- cells, cultured for 7 days in the presence of 20% IL-2, acquired the receptors for Leu-7.
(16) Single-parameter FACS analyses demonstrate a diminution in both B cell number and the heterogeneity of membrane Ag expression within the surviving B cell pool after irradiation.
(17) The mean age at the time of surgery was 72.7 years for the ophthalmologists and 66.4 years for the FACS members.
(18) Tumor kinetic parameters were evaluated by TLI and PDP-LI in 22 patients on serial tumor biopsies at diagnosis (TO), after DES (T1), 24 hrs after the first FAC (T2) and at the time of radical surgery (T3).
(19) Both TNF and TNF receptors are detectable on monocyte membranes by FACS analysis, and the levels of each are modulated by treatment with IFN-gamma.
(20) Using FACS analysis, this antigen does not appear to be cell cycle specific, and is exposed to the external cell surface.