What's the difference between facilitate and mediate?

Facilitate


Definition:

  • (v. t.) To make easy or less difficult; to free from difficulty or impediment; to lessen the labor of; as, to facilitate the execution of a task.

Example Sentences:

  • (1) The technique is facilitated by an amazingly low tendency to bleeding.
  • (2) beta-Endorphin blocked the development of fighting responses when a low footshock intensity was used, but facilitated it when a high shock intensity was delivered.
  • (3) of PLA2 caused marked degranulation of mast cells in the rat mesentery which was facilitated by addition of calcium ion (10 mM) but antagonized by pretreating with three antiinflammatory agents.
  • (4) It was also found that lipocortin I and ONO-RS-082, but not neomycin, facilitated the generation of GIF-producing T cells.
  • (5) The use of glucagon in double-contrast studies of the colon has been recommended for various reasons, one of which is to facilitate reflux of barium into the terminal ileum.
  • (6) As prolongation of the action potential by TEA facilitates preferentially the hormone release evoked by low (ineffective) frequencies, it is suggested that a frequency-dependent broadening of action potentials which reportedly occurs on neurosecretory neurones may play an important role in the frequency-dependent facilitation of hormone release from the rat neurohypophysis.
  • (7) Since the advance and return of sperm inside the tubes could facilitate the interaction of sperm with secretions participating in its maturation, the persistent infertility after vasectomy could be related to the contractile alteration that follows the excessive tubal distention.
  • (8) Recognition of the distinctive morphology of MH and the performance of ancillary studies on cytologic preparations should facilitate the rapid diagnosis and early treatment of this aggressive disease.
  • (9) Early recognition is facilitated by monitoring of arterial blood gas levels for hypoxemia.
  • (10) Local application of 8-OH-DPAT (0-5 micrograms) into the median raphe nucleus, facilitated male rat sexual behavior, as evidenced by a decrease in number of intromissions preceding ejaculation and in time to ejaculation.
  • (11) Implications for practice and research include need for support groups with nurses as facilitators, the importance of fostering hope, and need for education of health care professionals.
  • (12) The presence of these markers has facilitated the identification and characterization of the mononuclear cells in a number of animal and human lymphoid malignancies.
  • (13) The pathomechanism, how C. pylori facilitates the development of peptic ulcer is since hypothetical.
  • (14) It facilitated the acquisition of quantitative velocity information with standard Doppler ultrasound techniques by identifying areas of high velocity or turbulent flow and was invaluable in the assessment of anomalous pulmonary venous drainage occurring either as an isolated anomaly or in conjunction with complex intracardiac lesions.
  • (15) Unions have complained about the process for Chinese-backed companies to bring overseas workers to Australia for projects worth at least $150m, because the memorandum of understanding says “there will be no requirement for labour market testing” to enter into an investment facilitation arrangements (IFA).
  • (16) Preliminary rhythmic somatic stimulation has a predominantly facilitating effect on EPs appearing in response to tonal stimuli in the areas A1, S2, S1.
  • (17) Ten patients received intercostal nerve blockade on a total of 29 occasions in order to provide analgesia following liver transplantation and to facilitate weaning from artificial ventilation of the lungs.
  • (18) Technically speaking, this modality of brief psychotherapy is based on the nonuse of transferential interpretations, on impeding the regression od the patient, on facilitating a cognitice-affective development of his conflicts and thus obtain an internal object mutation which allows the transformation of the "past" into true history, and the "present" into vital perspectives.
  • (19) phenomena) and Facilitation Gradients (measuring E.T.
  • (20) Finally, a reciprocal facilitating effect of RRs and augmenting responses (ARs), which was studied by combined stimulation of nucleus ventralis posterolateralis (VPL) and NCM, appeared to be dependent upon an intracortical mechanism.

Mediate


Definition:

  • (a.) Being between the two extremes; middle; interposed; intervening; intermediate.
  • (a.) Acting by means, or by an intervening cause or instrument; not direct or immediate; acting or suffering through an intervening agent or condition.
  • (a.) Gained or effected by a medium or condition.
  • (a.) To be in the middle, or between two; to intervene.
  • (a.) To interpose between parties, as the equal friend of each, esp. for the purpose of effecting a reconciliation or agreement; as, to mediate between nations.
  • (v. t.) To effect by mediation or interposition; to bring about as a mediator, instrument, or means; as, to mediate a peace.
  • (v. t.) To divide into two equal parts.

Example Sentences:

  • (1) Stimulation of human leukocytes with various chemical mediators such as TPA, f-Met-Leu-Phe, LTB4, etc.
  • (2) Fibulin is a potential mediator of interactions between adhesion receptors and the cytoskeleton.
  • (3) Patients with papillary carcinoma with a good cell-mediated immune response occurred with much lower infiltration of the tumor boundary with lymphocyte whereas the follicular carcinoma less cell-mediated immunity was associated with dense lymphocytic infiltration, suggesting the biological relevance of lymphocytic infiltration may be different for the two histologic variants.
  • (4) The hypothesis that proteins are critical targets in free radical mediated cytolysis was tested using U937 mononuclear phagocytes as targets and iron together with hydrogen peroxide to generate radicals.
  • (5) We have investigated the effect of methimazole (MMI) on cell-mediated immunity and ascertained the mechanisms of immunosuppression produced by the drug.
  • (6) We determined whether serological investigations can assist to distinguish between chronic idiopathic autoimmune thrombocytopenia (cAITP) and immune-mediated thrombocytopenia in patients at risk to develop systemic lupus erythematosus (SLE); 82 patients were seen in this institution for the evaluation of immune thrombocytopenia.
  • (7) IgE-mediated acute systemic reactions to penicillin continue to be an important clinical problem.
  • (8) This induction is sensitive to actinomycin D but not to protein synthesis inhibitor puromycin, indicating an effect of estradiol at the transcriptional level, possibly mediated by the estrogen receptor.
  • (9) We sought additional evidence for an inverse relationship between functional CTL-target cell affinity on the one hand, and susceptibility of the CTL-mediated killing to inhibition by alpha LFA-1 and alpha Lyt-2,3 monoclonal antibodies on the other hand.
  • (10) Mannose receptor mediated uptake by the reticuloendothelial system has been suggested as an explanation for the rapid removal of ricin A chain antibody conjugates from the circulation after their administration.
  • (11) However, direct measurements of mediator release should be carried out to reach a firm conclusion.
  • (12) In addition to their involvement in thrombosis, activated platelets release growth factors, most notably a platelet-derived growth factor (PDGF) which may be the principal mediator of smooth muscle cell migration from the media into the intima and of smooth muscle cell proliferation in the intima as well as of vasoconstriction.
  • (13) Glutathion peroxidase and p-phenylenediamide-mediated peroxidase (PPD-peroxidase) were normal in leucocytes of 1 HPS patient.
  • (14) But MH162 was more effective than MRK16 in lymphocyte-mediated lysis of the MDR cells.
  • (15) Thus, human bronchial epithelial cells can express the IL-8 gene, with expression in response to the inflammatory mediator TNF regulated mainly at the transcriptional level, and with elements within the 5'-flanking region of the gene that are directly or indirectly modulated by the TNF signal.
  • (16) Tumour necrosis factor (TNF), a polypeptide produced by mononuclear phagocytes, has been implicated as an important mediator of inflammatory processes and of clinical manifestations in acute infectious diseases.
  • (17) From these results, it was suggested that the inhibitory effect of Cd on in vitro calcification of MC3T3-E1 cells may be due to both a depression of cell-mediated calcification and a decrease in physiochemical mineral deposition.
  • (18) injection of various inflammatory mediators, the vasopressor effect of i.a.
  • (19) It is concluded that fibroblast replication is an important mechanism leading to the pathologic fibrosis seen in graft versus host disease and, by analogy, probably other types of immunologically mediated fibrosis.
  • (20) The authors followed up the occurrence of inflammation-mediated osteopenia (IMO) in young and adult rats weighing 50 g and 150 g, respectively.