(v. i.) To be wanting; to fall short; to be or become deficient in any measure or degree up to total absence; to cease to be furnished in the usual or expected manner, or to be altogether cut off from supply; to be lacking; as, streams fail; crops fail.
(v. i.) To be affected with want; to come short; to lack; to be deficient or unprovided; -- used with of.
(v. i.) To fall away; to become diminished; to decline; to decay; to sink.
(v. i.) To deteriorate in respect to vigor, activity, resources, etc.; to become weaker; as, a sick man fails.
(v. i.) To perish; to die; -- used of a person.
(v. i.) To be found wanting with respect to an action or a duty to be performed, a result to be secured, etc.; to miss; not to fulfill expectation.
(v. i.) To come short of a result or object aimed at or desired ; to be baffled or frusrated.
(v. i.) To err in judgment; to be mistaken.
(v. i.) To become unable to meet one's engagements; especially, to be unable to pay one's debts or discharge one's business obligation; to become bankrupt or insolvent.
(v. t.) To be wanting to ; to be insufficient for; to disappoint; to desert.
(v. t.) To miss of attaining; to lose.
(v. i.) Miscarriage; failure; deficiency; fault; -- mostly superseded by failure or failing, except in the phrase without fail.
(v. i.) Death; decease.
Example Sentences:
(1) Intrathecal injection of zopiclone potentiated morphine antinociception, while the intracerebroventricular injection of zopiclone failed to enhance morphine antinociception and the intracerebroventricular injection of flumazepil to antagonize the intraperitoneal-zopiclone-induced increase in morphine antinociception.
(2) However, ticks, which failed to finish their feeding and represent a disproportionately great part of the whole parasite's population, die together with them and the parasitic system quickly restores its stability.
(3) The inquiry found the law enforcement agencies routinely fail to record the professions of those whose communications data records they access under Ripa.
(4) It is suggested that the normal cyclical release of LH is inhibited in PCO disease by a negative feedback by androgens to the hypothalamus or the pituitary, and that wedge resection should be reserved for patients in whom other forms of treatment have failed.
(5) Endoscopic retrograde cholangiography failed to demonstrate any bile ducts in the right postero-lateral segments of the liver, the "naked segment sign".
(6) Several efforts to extradite Polanski to California have failed.
(7) Administration of aminonucleoside and daunomycin produced proteinuria but did not cause a decrease in lipid P. Anticollagen and anti-lymphocyte sera that attached to the basement membrane but failed to produce proteinuria, also failed to affect the phospholipid content.
(8) An official inquiry into the Rotherham abuse scandal blamed failings by Rotherham council and South Yorkshire police.
(9) Amid the acrimony of the failed debate on the Malaysia Agreement, something was missed or forgotten: many in the left had changed their mind.
(10) Four of the nine patients failed to show any clinical or hematological improvement.
(11) In cases in which CT was also performed, it revealed corresponding hypodensities in two infarctions, but failed to reveal the foci of gliosis (or noncavital infarction), demyelination, or brain cyst.
(12) Even in the failed cases, 25-42% of subjects considered the treatment as good.
(13) Dzeko he has failed to hold down a starting berth since his £27m move in January 2011.
(14) Prothrombin isolation on DEAE Sephadex failed to separate the abnormal population (prothrombin Clamart) from the normal one.
(15) The starting point is the idea that the current system, because it works against biodiversity but fails to increase productivity, is broken.
(16) Other than failing to get a goal, I couldn’t ask for anything more.” From Lambert’s perspective there was an element of misfortune about the first and third goals, with Willian benefitting from handy ricochets on both occasions.
(17) In contrast, albino rats and rabbits failed to succumb to overt disease by subcutaneous and intraperitoneal routes of inoculation.
(18) It was recently demonstrated that MRL-lpr lymphoid cells transferred into lethally irradiated MRL- +mice unexpectedly failed to induce the early onset of lupus syndrome and massive lymphadenopathy of the donor, instead they caused a severe wasting syndrome resembling graft-vs-host (GvH) disease.
(19) In the controlled wound care group, only three ulcers in three patients achieved complete healing; the remaining 24 ulcers in 20 patients failed to achieve even 50% healing in the stipulated 3-month period.
(20) The former Stoke City manager Pulis had reportedly been left frustrated by the club failing to push through deals for various players he targeted to strengthen the Palace squad.
Overload
Definition:
(v. t.) To load or fill to excess; to load too heavily.
(n.) An excessive load; the excess beyond a proper load.
Example Sentences:
(1) By means of rapid planar Hill type antimony-bismuth thermophiles the initial heat liberated by papillary muscles was measured synchronously with developed tension for control (C), pressure-overload (GOP), and hypothyrotic (PTU) rat myocardium (chronic experiments) and after application of 10(-6) M isoproterenol or 200 10(-6) M UDCG-115.
(2) In iron-overloaded patients with primary haemochromatosis, there was inappropriately high uptake of iron by the biopsy specimens.
(3) The patient presented urgently for Caesarean section, with fluid overload and worsening thrombocytopaenia.
(4) Al hepatocytes overload appeared only in nuclei and not in nuclei and not in lysosomes, contrarily to chronic intoxications.
(5) Fluid overload, which could have been caused by the hyperosmolar properties of dextran, worsened progressively as fluids were drawn from the interstitial space and urine output was reduced.
(6) There were no significant differences between the mean levels of peak blood pressures (systolic, diastolic and mean), degree of fluid overload, and fractional sodium excretion in the 2 groups.
(7) Persisting diastolic dysfunction with a substantial rise in left ventricular filling pressure can be observed during dynamic exercise in postoperative patients with preoperative severe pressure overload hypertrophy.
(8) The 8 men and 3 women were clinically stable, were known to be compliant, and had no clinical evidence of aluminum overload; they were not receiving vitamin D supplements; and they had been on dialysis for an average of 65.6 months (range: 13-188 months).
(9) Wilson disease is due to a genetically determined impairment of copper excretion from liver into bile resulting in copper overload of the organism.
(10) There was no change in the sarcolemmal Mg2+ -ATPase of the left or right ventricle for the whole duration (3 to 9 months) of left ventricular pressure overload.
(11) These experimental results demonstrate that aluminium interferes with iron absorption and iron transfer, and suggest that these mechanisms may be responsible for maintaining and even increasing the anaemia observed in aluminium overload.
(12) When a high dose of the complex was administered, an overloading with hemosiderin of macrophages and hepatocytes was noticed.
(13) The subsequent accumulation of Na+ in the cell Na(+)-Ca2+ exchange, which can ultimately result in intracellular Ca2+ overload, contractile dysfunction and damage.
(14) If overloaded, these areas are subject to "cervical cratering," a common prelude to implant failure.
(15) The rationale for the inclusion of Mg in cardioplegic solutions therefore lies not in its cardioplegic properties, but in its ability to influence other cellular events such as the loss of Mg and K and perhaps to counter the detrimental effects of ischemia by antagonizing calcium (Ca) overload.
(16) Cardiac hypertrophy due to a chronic hemodynamic overload is accompanied by isoformic changes of two proteins of the thick filament of the sarcomere, myosin, and creatine phosphokinase.
(17) Age, gender and laboratory markers of iron overload did not differentiate patients with cardiac dysfunction (group 1) from those without cardiac dysfunction (group 2).
(18) Severe overloading can increase microdamage alarmingly, its repair by BMUs too, and can cause woven bone formation, anarchic resorption and a regional acceleratory phenomenon.
(19) Thus, it appears that the increased expression of the regulatory MLC2 gene in SHR atrial cells is a predetermined event, which, most likely, participates in functional adaptation of the myocardium in response to pressure overload and subsequent hypertrophy.
(20) To help resolve the issue of contractile function in volume overload hypertrophy, we examined ventricular function in a recently described model of severe chronic experimental mitral regurgitation.