(1) In contrast, TTR(Met30) was relatively enriched in cerebrospinal fluid samples from two FAP patients.
(2) Haplotype analysis revealed that the Val----Met mutation has recurred frequently in the population to generate the FAP families of independent origins.
(3) An informative Dutch pedigree showed that two other linked polymorphic DNA markers, Pi227 and YN5.48, closely flank the FAP locus, one on either side.
(4) Studies of the molecular genetics of colon cancer have identified acquired alterations in oncogenes such as the K-ras gene and in putative tumor suppressor genes such as the FAP gene on chromosome 5, the p53 gene on chromosome 17, and the DCC gene on chromosome 18, which appear to mediate important steps in the adenoma-dysplasia-carcinoma sequence.
(5) The tumors themselves were FAP protein negative, as were the nonpancreatic tumors and normal organs.
(6) These clinical features closely resembled familial amyloid polyneuropathy (FAP), but abnormal serum prealbumin levels, specific to FAP (Japanese type), were not detected by radioimmunoassay; DNA sequence for prealbumin was normal.
(7) In FAP group (7 males and 5 females) the average age was 55 (range 30 to 74).
(8) Other probes, however, should be useful for assessing FAP inheritance by restriction fragment length polymorphism analysis, for presymptomatic diagnosis of the disease.
(9) Proteins with lower molecular weight than the PA monomer were major proteins in both SSA and FAP fibrils.
(10) Colchicine or Dimethyl-Sulphoxide (DMSO) treatment may prevent the development of FAP.
(11) Genomic DNA was isolated from peripheral blood lymphocytes of a patient with familial amyloidotic polyneuropathy (FAP) and the transthyretin (TTR) gene examined for sequence mutations.
(12) Patients with FAP develop multiple benign colorectal tumors.
(13) A recent study of FAP (5-FU, doxorubicin, cisplatin) has reported a 50% response rate with a significant number of CRs.
(14) Other dominantly-inherited colorectal cancer syndromes produce less striking phenotypes, but affect far more individuals than FAP.
(15) Sialic acid heterogeneity probably has a genetic basis, but this is not associated with the genetic defect underlying FAP.
(16) MF was found most often in FAP patients with associated extra-colonic "Gardner" signs (19 patients) and those who had had previous abdominal surgery (20 patients).
(17) This is the first report of chromosome 18 allele loss in colorectal carcinomas from FAP patients and concurrent allele losses on chromosomes 5 and 18 in sporadic colorectal cancer.
(18) Subsequent linkage analysis in six pedigrees, three having the FPC phenotype and three segregating GS, placed the FAP locus very close to a new marker, YN5.48 (D5S81), that is approximately 17 centimorgans distal to C11p11 on the genetic map.
(19) In a prospective study, 34 patients at 50% risk of inheriting FAP were examined.
(20) The coexistence of populations with severe duodenal and rectal polyposis suggests that environmental factors are important in phenotypic expression in FAP.
Fop
Definition:
(n.) One whose ambition it is to gain admiration by showy dress; a coxcomb; an inferior dandy.
Example Sentences:
(1) This replication based activation is, however, cell type dependent and was seen in FOP cells but not in 3T6 cells.
(2) Patients with FOP may present problems to the anaesthetist, including difficulties with tracheal intubation, restrictive pulmonary disease and abnormalities of cardiac conduction.
(3) A 14-yr-old boy with fibrodysplasia ossificans progressiva (FOP) presented for surgery for bilateral division of his ossified masseter muscles.
(4) Surgery to remove joint-bridging ossifications in FOP is not recommended.
(5) The case report of a patient with clinically and histologically confirmed FOP is described to emphasize the advantages of administering Bleomycin intra-arterially (external carotid artery) by means of a Holter catheter.
(6) There's the enmity between husband and wife flung together in a loveless marriage expressed in a series of caustic asides to the audience, and the idiocy of Lord Are, who bears all the hallmarks of the fops Restoration audiences loved to laugh at.
(7) However, it is not possible to definitely establish the malignant or benign nature of FOP in this manner.
(8) The acute process of FOP was thereby distinguished from that of osteomyelitis by use of CT scan.
(9) In a sporadic case of FOP treated for 6 years with a diphosphonate (EHDP) we have analyzed the findings from CT.
(10) Considering the complexity and difficulty of the mentioned method for its practical usage, a simplified method is proposed; a registration of FOP of a stable state with the incidence of stimulations of 33 Hz, that allows to detect cases of pathology with visual acuity not less than 0.2.
(11) Texas pool party incident raises questions about wealth and race Read more McKinney Fraternal Order of Police Lodge #107, the union that represents city police officers, insisted in a statement that the pool party incident was not an example of racism: “The McKinney FOP assures that this was not a racially motivated incident and can say without a shadow of doubt that all members of the McKinney FOP and McKinney PD do not conduct racially biased policing.” The union also clarified that it does not condone officers cursing at juveniles or adult citizens.
(12) This report concerns an 11-year-old boy suffering from FOP, who presented significant modification of the musculoskeletal structure of the thorax and problems with articular movements.
(13) The developmental similarities between decapentaplegic in the fly and FOP in man suggest a useful model for the study of FOP.
(14) Informativeness of different methods used for registration of optic generated potentials in response to light flash (FOP) has been studied in 27 healthy persons and 21 patients (32 eyes) with partial atrophy of the optic nerve.
(15) Ruskin, played by Joshua McGuire, is a simpering Blackadderish caricature of an art intellectual: a lisping, red-headed, salon fop.
(16) The successful treatment of FOP points out the possibility of employing a Holter catheter for administering cytostatic agents in the treatment of malignant neoplasms in the facial area.
(17) An 8-year-old boy presenting with fever, neck pain, and torticollis was eventually diagnosed as having fibrodysplasia ossificans progressiva (FOP).
(18) The present study demonstrated that in macaque monkeys, tactile sensation of the oral cavity is represented on areas 3, 1-2 and G in the Fop as well as on the surrounding areas (e.g., area 6 and the insula), and taste sensation on areas G and 1-2 and the insula.
(19) We reevaluated the published data on the natural history of FOP and discovered an array of developmental gradients (characteristic patterns of disease expression) similar to developmental anomalies induced by pleiotropic mutations of the decapentaplegic (dpp) locus in Drosophila melanogaster.
(20) The cytoplasm of tumor cells from a subdermal nodule in a patient with fibrodysplasia ossificans progressiva (FOP) exhibited intense enzymatic activity in cryostat sections processed for demonstration of alkaline phosphatase.