(1) In contrast, TTR(Met30) was relatively enriched in cerebrospinal fluid samples from two FAP patients.
(2) Haplotype analysis revealed that the Val----Met mutation has recurred frequently in the population to generate the FAP families of independent origins.
(3) An informative Dutch pedigree showed that two other linked polymorphic DNA markers, Pi227 and YN5.48, closely flank the FAP locus, one on either side.
(4) Studies of the molecular genetics of colon cancer have identified acquired alterations in oncogenes such as the K-ras gene and in putative tumor suppressor genes such as the FAP gene on chromosome 5, the p53 gene on chromosome 17, and the DCC gene on chromosome 18, which appear to mediate important steps in the adenoma-dysplasia-carcinoma sequence.
(5) The tumors themselves were FAP protein negative, as were the nonpancreatic tumors and normal organs.
(6) These clinical features closely resembled familial amyloid polyneuropathy (FAP), but abnormal serum prealbumin levels, specific to FAP (Japanese type), were not detected by radioimmunoassay; DNA sequence for prealbumin was normal.
(7) In FAP group (7 males and 5 females) the average age was 55 (range 30 to 74).
(8) Other probes, however, should be useful for assessing FAP inheritance by restriction fragment length polymorphism analysis, for presymptomatic diagnosis of the disease.
(9) Proteins with lower molecular weight than the PA monomer were major proteins in both SSA and FAP fibrils.
(10) Colchicine or Dimethyl-Sulphoxide (DMSO) treatment may prevent the development of FAP.
(11) Genomic DNA was isolated from peripheral blood lymphocytes of a patient with familial amyloidotic polyneuropathy (FAP) and the transthyretin (TTR) gene examined for sequence mutations.
(12) Patients with FAP develop multiple benign colorectal tumors.
(13) A recent study of FAP (5-FU, doxorubicin, cisplatin) has reported a 50% response rate with a significant number of CRs.
(14) Other dominantly-inherited colorectal cancer syndromes produce less striking phenotypes, but affect far more individuals than FAP.
(15) Sialic acid heterogeneity probably has a genetic basis, but this is not associated with the genetic defect underlying FAP.
(16) MF was found most often in FAP patients with associated extra-colonic "Gardner" signs (19 patients) and those who had had previous abdominal surgery (20 patients).
(17) This is the first report of chromosome 18 allele loss in colorectal carcinomas from FAP patients and concurrent allele losses on chromosomes 5 and 18 in sporadic colorectal cancer.
(18) Subsequent linkage analysis in six pedigrees, three having the FPC phenotype and three segregating GS, placed the FAP locus very close to a new marker, YN5.48 (D5S81), that is approximately 17 centimorgans distal to C11p11 on the genetic map.
(19) In a prospective study, 34 patients at 50% risk of inheriting FAP were examined.
(20) The coexistence of populations with severe duodenal and rectal polyposis suggests that environmental factors are important in phenotypic expression in FAP.
Session
Definition:
(n.) The act of sitting, or the state of being seated.
(n.) The actual sitting of a court, council, legislature, etc., or the actual assembly of the members of such a body, for the transaction of business.
(n.) Hence, also, the time, period, or term during which a court, council, legislature, etc., meets daily for business; or, the space of time between the first meeting and the prorogation or adjournment; thus, a session of Parliaments is opened with a speech from the throne, and closed by prorogation. The session of a judicial court is called a term.
Example Sentences:
(1) The effects of sessions, individual characteristics, group behavior, sedative medications, and pharmacological anticipation, on simple visual and auditory reaction time were evaluated with a randomized block design.
(2) Accuracy of discrimination of letters at various preselected distances was determined each session while Ortho-rater examinations were given periodically throughout training.
(3) Twenty volunteers were used for the measurement of pedal pressures for 15 trials during three separate sessions.
(4) In common with other studies, we found that the injury occurred in competitive runners, especially females, and was likely to develop during competitive races or intensive training sessions.
(5) With feedback, the rate of decrease in error over sessions was similiar for both levels of IQ.
(6) lengths with the subjects equally divided into these four groups: distributed trials, distributed sessions; distributed trials, massed sessions; massed trials, distributed sessions; and massed trials, massed sessions.
(7) In a second set of test sessions, volunteers chewed sugarless gum for 10 minutes, starting 15 minutes after they ate the snack food.
(8) Successful extraction occurred during a single session in 125 of 219 patients (57%); 60 of 219 patients required two extraction sessions.
(9) This paper describes a teaching process in which two 4th year medical students learn a family approach to problem solving during a short clerkship of twelve hours spread over four weekly sessions.
(10) Superior memory for the word list was found when the odor present during the relearning session was the same one that had been present at the time of initial learning, thereby demonstrating context-dependent memory.
(11) On the reaction time task no main effects were found but the time X drinker category interaction was significant; in session 1 LSD's RT were shorter than those of HSD.
(12) Therefore, a study using 2-dimensional and M-mode backscatter imaging was performed in 20 normal male subjects by 2 observers at an initial session and by 1 of the observers after 1 week.
(13) The effects of learning history were evident on sessions 4 and 5 when the same consequence was contingent upon the performance of all groups.
(14) Chapter three Administration of the camps The preparatory camp is the first home and school of the mujahid in which his military and jihadi training sessions take place and he undergoes sufficient education in matters of his religion, life and jihad.
(15) Twenty-four hours later, a stimulus generalization test was conducted in the absence of drug; during this session, tones that varied in frequency around 4.5 KHz were presented while the animals were responding under the VI schedule.
(16) When S+ followed cocaine, stereotyped bar-pressing developed with markedly increased responding during the remainder of the session.
(17) In the other component, the discriminative stimuli were the same each session (performance).
(18) Efferent units with spontaneous activity were uncommon at the start of the recording sessions but were more frequently encountered later in the experiments.
(19) Seventy male subjects participated in a six session study of feedback-mediated heart rate modification.
(20) In 92 percent of the patients the thoraco-abdominal aorta and its branches were well documented on 2 orthogonal projections performed in one single session.