(a.) Pertaining to, or derived from, iron; -- especially used of compounds of iron in which the iron has its lower valence; as, ferrous sulphate.
Example Sentences:
(1) The free radical scavengers mannitol, thiourea, benzoate, and 4-methylmercapto-2-oxobutyrate protected either native cells exposed to H2O2 or pretreated hepatocytes exposed to H2O2 and given ferric or ferrous iron.
(2) The pH dependence of this spectral change gave a sigmoidal curve fitted well to a theoretical curve of a cooperative release of two protons with a pK value of 7.5, indicating the existence of the acidic and alkaline forms of the ferrous CO enzyme.
(3) Iron presented as inorganic ferric or ferrous salts may also be absorbed, though the more soluble ferrous salts are adsorbed much more rapidly.
(4) The oxygen-free radical scavengers thiourea, mannitol and catalase prevented toxicity mediated by ferrous ammoniumsulphate but not by ferrous ascorbate (molar ratio of 1:20).
(5) One was identified as viridomycin A, the ferrous chelate of 4-hydroxy-3-nitrosobenzaldehyde; the second (actinoviridin A) was the corresponding carboxylic acid chelate and the third (viridomycin E) was a hybrid chelate containing both the aldehyde and acid ligands.
(6) The ferrous iron chelator, bipyridyl, enhanced the production of chemiluminescence catalyzed by FeSO4 and ferritin but had little effect on the K3Fe(CN)6-catalyzed reaction.
(7) Under aerobic conditions, adriamycin-Fe3+ caused a reduction of cytochrome c and ferrous iron formed spontaneously.
(8) EPR studies of intact cells grown photoheterotrophically reveal that in situ cytochrome c' exists largely in the ferrous state.
(9) Ferric ammonium citrate, ferrous sulfate and ferrous gluconate were all found effective in preventing rat anemia when added to their drinking water.
(10) Of several heavy metal ions, such as Fe3+, Fe2+, Co2+, Ni2+, Cu2+ and Zn2+, tested for supplementation of the alkaline growth deficiency, only iron, either added in the ferrous or ferric form, was able to restore cellular growth.
(11) Prolonged continuous cultivation on tetrathionate or thiosulfate did not affect the ability of the organism to grow subsequently in ferrous iron medium.
(12) Fatale haemoptysis occurred as a result of circumferential caustic erosion to the right intermediate bronchus caused by a tablet of ferrous sulphate which remained in contact for 4 days.
(13) Ferrous ions stimulate NAD(P)H oxidation, which is again inhibited by SOD and catalase.
(14) Bio-availability and therapeutic efficacy of two oral ferrous preparations in the form of effervescent tablets (A and A*) were compared.
(15) The reaction of ferrous bleomycin with dioxygen is reexamined to clarify whether radical species derived from molecular oxygen are generated.
(16) The hydroxylase was a monomer with a Mr of 35,000-38,000. alpha-Ketoglutarate, ferrous iron, and molecular oxygen were required for the enzyme activity.
(17) The spontaneous activity of 24 cells was reduced by ferrous ions.
(18) It was classified as a metallo-protease by virtue of its inactivation by metal-ion chelators and reactivation by ferrous ions.
(19) Regulation by iron occurs at the transcriptional level and is mediated by a ferrous iron binding protein designated Fur (ferric uptake regulation).
(20) The anticonvulsant effects of D-alpha-tocopherol (vitamin E) were studied in 4 animal seizure models: the Metrazol threshold model (MET), the maximal electroshock model (MES), the kindling model (well-established seizures), and the ferrous chloride model.
Iron
Definition:
(n.) The most common and most useful metallic element, being of almost universal occurrence, usually in the form of an oxide (as hematite, magnetite, etc.), or a hydrous oxide (as limonite, turgite, etc.). It is reduced on an enormous scale in three principal forms; viz., cast iron, steel, and wrought iron. Iron usually appears dark brown, from oxidation or impurity, but when pure, or on a fresh surface, is a gray or white metal. It is easily oxidized (rusted) by moisture, and is attacked by many corrosive agents. Symbol Fe (Latin Ferrum). Atomic weight 55.9. Specific gravity, pure iron, 7.86; cast iron, 7.1. In magnetic properties, it is superior to all other substances.
(n.) An instrument or utensil made of iron; -- chiefly in composition; as, a flatiron, a smoothing iron, etc.
(n.) Fetters; chains; handcuffs; manacles.
(n.) Strength; power; firmness; inflexibility; as, to rule with a rod of iron.
(n.) Of, or made of iron; consisting of iron; as, an iron bar, dust.
(n.) Resembling iron in color; as, iron blackness.
(n.) Like iron in hardness, strength, impenetrability, power of endurance, insensibility, etc.;
(n.) Rude; hard; harsh; severe.
(n.) Firm; robust; enduring; as, an iron constitution.
(n.) Inflexible; unrelenting; as, an iron will.
(n.) Not to be broken; holding or binding fast; tenacious.
(v. t.) To smooth with an instrument of iron; especially, to smooth, as cloth, with a heated flatiron; -- sometimes used with out.
(v. t.) To shackle with irons; to fetter or handcuff.
(v. t.) To furnish or arm with iron; as, to iron a wagon.
Example Sentences:
(1) The hypothesis that proteins are critical targets in free radical mediated cytolysis was tested using U937 mononuclear phagocytes as targets and iron together with hydrogen peroxide to generate radicals.
(2) The most successful dyes were phenocyanin TC, gallein, fluorone black, alizarin cyanin BB and alizarin blue S. Celestin blue B with an iron mordant is quite successful if properly handled to prevent gelling of solutions.
(3) These membrane perturbation effects not observed with bleomycin-iron in the presence of a hydroxyl radical scavenger, dimethyl thiourea, or a chelating agent, desferrioxamine, were correlated with the ability of the complex to generate highly reactive oxygen species.
(4) The specific activities of extracts from cells grown under phototrophic and aerobic conditions were similar and not affected by the concentration of iron in the growth media.
(5) In the 153 women to whom iron supplements were given during pregnancy, the initial fall in haemoglobin concentration was less, was arrested by 28 weeks gestation and then rose to a level equivalent to the booking level.
(6) Typically the iron-iron axis (gz) of the binuclear iron-sulfur clusters is in the membrane plane.
(7) Increased iron levels in basal ganglia were generally associated with normal or elevated levels of ferritin immunoreactivity, for example, the substantia nigra in PSP and possibly MSA, and in putamen in MSA.
(8) Lead levels in contents and shells of eggs laid by hens dosed with all-lead shot were about twice those in eggs laid by hens dosed with lead-iron shot.
(9) Dietary factors affect intestinal P450s markedly--iron restriction rapidly decreased intestinal P450 to beneath detectable values; selenium deficiency acted similarly but was less effective; Brussels sprouts increased intestinal AHH activity 9.8-fold, ECOD activity 3.2-fold, and P450 1.9-fold; fried meat and dietary fat significantly increased intestinal EROD activity; a vitamin A-deficient diet increased, and a vitamin A-rich diet decreased intestinal P450 activities; and excess cholesterol in the diet increased intestinal P450 activity.
(10) Since iron from fortified formulas is well absorbed during the first three months of life, even if it is not immediately used for hemoglobin formation, an inccrease in the iron stores will occur...
(11) Dietary intakes, measured by three 24-hour recalls, revealed that protein, iron and Vitamin C generally met or exceeded the Nutrition Recommendations for age.
(12) This is a struggle for the survival of our nation.” As ever, after Trump’s media dressing-down, his operation was quick to fit a velvet glove to an iron fist.
(13) Ten weeks of iron therapy was not, however, long enough to increase iron stores.
(14) With both approaches, carbohydrate and fat had little influence whereas egg albumin had a significant inhibitory effect on the absorption of nonheme iron.
(15) The protein quality and iron bioavailability of mechanically deboned turkey meat (MDT) and hand-deboned turkey meat (HDT) were determined in rats.
(16) Serum levels of vitamins A and E, zinc and iron were determined in healthy control subjects and lepromatous leprosy patients belonging to an eastern state of India.
(17) Ferric iron in aqueous solution was used as an iron-only control.
(18) The implications of inhibition of protein kinase C by adriamycin-iron(III) are discussed.
(19) The duodenal mucosa of genotypically normal iron replete and iron deficient mice and mice with sex-linked (sla) and microcytic anemias (mk) was examined for the presence of iron-binding proteins.
(20) Ferredoxin reductase (Fd-reductase) supplies reducing equivalents obtained from NADPH to mitochondrial cytochrome P450 enzymes via the small iron-sulfur protein ferredoxin.