What's the difference between fever and pyrogen?

Fever


Definition:

  • (n.) A diseased state of the system, marked by increased heat, acceleration of the pulse, and a general derangement of the functions, including usually, thirst and loss of appetite. Many diseases, of which fever is the most prominent symptom, are denominated fevers; as, typhoid fever; yellow fever.
  • (n.) Excessive excitement of the passions in consequence of strong emotion; a condition of great excitement; as, this quarrel has set my blood in a fever.
  • (v. t.) To put into a fever; to affect with fever; as, a fevered lip.

Example Sentences:

  • (1) The simultaneous administration of the yellow fever vaccine did not influence the titre of agglutinins induced by the classic cholera vaccine.
  • (2) It has also been reported in a severe form with fever and systemic symptoms both in children and adults.
  • (3) This paper analyzes the nucleotide sequences of three viruses: Kunjin, west Nile, and yellow fever.
  • (4) Twelve strains of the Crimean hemorrhagic fever (CHF)-Congo group of viruses the Bunyaviridae family were investigated with respect to sensitivity to lipid solvents and temperature, pathogenicity for animals, interactions with cell cultures and antigenic relationships.
  • (5) A 45-year-old woman was admitted to our hospital with complaints of fever and lumbago.
  • (6) Although the incidence of acute rheumatic fever has declined in the last decades, a few outbreaks have recently been reported.
  • (7) The clinical features were fever, anemia, and pulmonary embolism.
  • (8) No cases of rheumatic fever and no acute nephritis appeared in spite of the vigorous immune response to both cellular and extracellular antigens of group A streptococci documented in 50% to 80% of patients, suggesting that strain variation may be a feature of rheumatogenicity as well as nephritogenicity of group A streptococcal pharyngitis.
  • (9) imbalance between production and elimination of heat, or to fever, i.e.
  • (10) Early diagnosis (fever, increase of leucocytes and toxic signs in differential blood count, thrombocythemia, decrease of anorganic phosphate), prophylaxis, and treatment are discussed.
  • (11) All of them had fever, jaundice, abdominal pain, leucocytosis and deranged liver function while 26.6% were in shock, 13.3% in coma and 40% in azotaemia.
  • (12) On land, the pits' stagnant pools of water become breeding grounds for dengue fever and malaria.
  • (13) Most cases of typhoid fever in the United States occur in international travelers, with the greatest risk associated with travel to Peru, India, Pakistan, and Chile.
  • (14) Thirty-six per cent of 972 patients developed fever (temperature exceeding 38 degrees C).
  • (15) Fever was also associated with a higher incidence of lymphopenia, hyponatraemia, hypoalbuminaemia and many acid-fast bacilli on sputum smear.
  • (16) --The frequency of common clinical manifestations (eg, headache, fever, and rash) and laboratory findings (eg, leukocyte and platelet counts and serum chemistry abnormalities) of patients with infectious diseases was tabulated.
  • (17) We describe a patient with rheumatoid arthritis (RA) who developed hypersensitivity after 3 weeks of therapy with azathioprine with fever, jaundice and renal insufficiency.
  • (18) Pichinde virus inoculation into strain 13 guinea pigs is a model with features reputed to be similar to hemorrhagic fever in humans.
  • (19) A case of post streptococcal acute glomerulonephritis co-existing with acute rheumatic fever is reported.
  • (20) The immunofluorescent method is rapid and simple, and is recommended for routine detection of serum antibody in dengue hemorrhagic fever.

Pyrogen


Definition:

  • (n.) Electricity.
  • (n.) A poison separable from decomposed meat infusions, and supposed to be formed from albuminous matter through the agency of bacteria.

Example Sentences:

  • (1) Central injections of 40 and 80 ng of [Nle4,D-Phe7]-alpha-MSH caused hypothermia in afebrile rabbits, whereas 20 and 10 ng, which had no effect on afebrile body temperature, caused greater than 40% reduction in leukocytic pyrogen-induced fever.
  • (2) In the active phase all the patients exhibited an abrupt increase in the activity of alkaline and acid phosphatase in blood neutrophils, a drop in the level of CP (in 69%), a rise in the activity of MP (in 32%); pyrogenal did not induce any capacity for restoring HCT (in 44%).
  • (3) MAbs W1-W3 derived from mice, which were immunized with whole cells of the strain Moulton, reacted with the serogroups Canicola, Icterohaemorrhagiae and Pyrogenes.
  • (4) Interleukin-1 alpha (IL-1 alpha) and interleukin-1 beta (IL-1 beta) are thought to be endogenous pyrogens, i.e., to mediate fever production; warm-sensitive (W) and cold-sensitive (C) neurons in the preoptic area (POA) are presumed to be the ultimate targets of endogenous pyrogens.
  • (5) The Limulus amebocyte lysate test has been used for determination of pyrogens in sugar of different qualities.
  • (6) The minimum pyrogenic dose in both new-born and adult guinea-pigs was 0.25 microliter, but the 0 to 5-day old animals which responded with a fever to this dose were few in number and large in weight; 'small-for age' neonates became hypothermic.
  • (7) Twelve serovars included in the study were: australis, autumnalis, ballum, bataviae, bratislava, canicola, copenhageni, grippotyphosa, hardjo, pomona, pyrogenes, and tarassovi.
  • (8) Another property shared by IL 1 and IL 6 is their pyrogenicity.
  • (9) IL-6 induction was also observed after pretreatment with indomethacin, indicating that the effect was dissociated from the pyrogenic activity of IL-1.
  • (10) Protein malnutrition leads to diminished pyrogenicity of macrophage culture supernatants and may be at least partly responsible for the decreased febrile response seen in the malnourished animals.
  • (11) In its monomer form, endogenous pyrogen is a potent fever-producing substance and mediates fever by its action on the thermoregulatory center.
  • (12) Immobilized histidine and immobilized histamine could be used for the removal of natural pyrogens contaminating various useful low-molecular-weight compounds as well as high-molecular-weight compounds such as proteins.
  • (13) Reusing hemodialyzers more than 20 times and, in some instances, also using manual reprocessing systems was significantly associated with clustering of pyrogenic reactions regardless of the type of germicide used.
  • (14) The effects of various kinds of drugs on the pyrogenicity of toxic shock syndrome toxin 1 (TSST-1) and its capacity to enhance the lethal effects of endotoxin in rabbits were studied.
  • (15) The hyperthermic response to pyrogen was not potentiated by caffeine or theophylline administered i.p.
  • (16) With regard to Group I, there was a high number of positive (32.3%) and a variation in the frequency of serovars, the results being as follows: L. butembo (38.8%), L. pomona (33.3%), L. bratislava (31.4%), L. icterohemorragica (12.9%), L. borincana (3.7%) and finally L. canicola, L. pyrogenes, L. wolffii and L. bataviae (1.8%).
  • (17) Parenterals, sterile preparations intended to be injected in man or animal, should be free from pyrogenic substances which are able to raise the thermostatic setting in the hypothalamus.
  • (18) Titers for Leptospira interrogans serovars grippotyphosa, pyrogenes, djasiman, butembo, and pomona were demonstrated.
  • (19) The fever responses of the animals were remeasured 3 days later, and in every case there was a marked enhancement of the fevers produced, using the same doses of endogenous pyrogen that were used earlier.
  • (20) The results were compared with rabbit pyrogen tests.

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