(a.) Preceding all others of a series or kind; the ordinal of one; earliest; as, the first day of a month; the first year of a reign.
(a.) Foremost; in front of, or in advance of, all others.
(a.) Most eminent or exalted; most excellent; chief; highest; as, Demosthenes was the first orator of Greece.
(adv.) Before any other person or thing in time, space, rank, etc.; -- much used in composition with adjectives and participles.
(n.) The upper part of a duet, trio, etc., either vocal or instrumental; -- so called because it generally expresses the air, and has a preeminence in the combined effect.
Example Sentences:
(1) First results let us assume that clinically silent TIAs also (in analogy to clinically silent brain infarctions) could be detected and located.
(2) Here we report that sperm from psr males fertilizes eggs, but that the paternal chromosomes are subsequently condensed into a chromatin mass before the first mitotic division of the egg and do not participate in further divisions.
(3) However, when first trimester specimens were analyzed, the direct-product measurements were significantly larger than the corresponding 3H2O assay results.
(4) In Patient 2 they were at first paroxysmal and unformed, with more prolonged metamorphopsia; later there appeared to be palinoptic formed images, possibly postictal in nature.
(5) Van Persie's knee injury meant that Mata could work in tandem with the delightfully nimble Kagawa, starting for the first time since 22 January.
(6) These studies led to the following conclusions: (a) all the prominent NHP which remain bound to DNA are also present in somewhat similar proportions in the saline-EDTA, Tris, and 0.35 M NaCl washes of nuclei; (b) a protein comigrating with actin is prominent in the first saline-EDTA wash of nuclei, but present as only a minor band in the subsequent washes and on washed chromatin; (c) the presence of nuclear matrix proteins in all the nuclear washes and cytosol indicates that these proteins are distributed throughout the cell; (d) a histone-binding protein (J2) analogous to the HMG1 protein of K. V. Shooter, G.H.
(7) The issue of the Schizophrenia Bulletin is devoted to articles representing this full range of conceptual and empirical work on first-episode psychosis.
(8) We conclude that first-transit and blood-pool techniques are equally accurate methods for determining EF when the time-activity method of analysis is employed.
(9) Oculomotor paresis with cyclic spasms is a rare syndrome, usually noticeable at birth or developing during the first year of life.
(10) In early 2000, during the first months of Vladimir Putin’s presidency, Babitsky was kidnapped by Russian forces and disappeared for many weeks.
(11) The Frenchman’s 65th-minute goal was a fifth for United and redemptive after he conceded the penalty from which CSKA Moscow took a first-half lead.
(12) The intrauterine mean active pressure (MAP) in the nulliparous group was 1.51 kPa (SD 0.45) in the first stage and 2.71 kPa (SD 0.77) in the second stage.
(13) For the first time it was organized on the basis of population.
(14) Immunocompetence was also evident when the cells from thymectomized donors were first incubated with thymus extract for 1 hr and subsequently tested for reactivity.
(15) gamma-Aminobutyric acid (GABA) and glutamate release from the treated side was higher than the control value during the first 2-3 h, a result indicating an important role of glial cells in the inactivation of released transmitter.
(16) The results of the evaluation confirm that most problems seen by first level medical personnel in developing countries are simple, repetitive, and treatable at home or by a paramedical worker with a few safe, essential drugs, thus avoiding unnecessary visits to a doctor.
(17) Complementarity determining regions (CDR) are conserved to different extents, with the first CDR region in all family members being among the most conserved segments of the molecule.
(18) Despite of the increasing diagnostic importance of the direct determination of the parathormone which is at first available only in special institutions in these cases methodical problems play a less important part than the still not infrequent appearing misunderstanding of the adequate basic disease.
(19) The present findings indicate that the deafferented [or isolated] hypothalamus remains neuronally isolated from the environment if the operation is carried out later than the end of the first week of life.
(20) Amino acid sequence analysis showed that both peaks had identical N-terminal sequences through the first 28 residues.
General
Definition:
(a.) Relating to a genus or kind; pertaining to a whole class or order; as, a general law of animal or vegetable economy.
(a.) Comprehending many species or individuals; not special or particular; including all particulars; as, a general inference or conclusion.
(a.) Not restrained or limited to a precise import; not specific; vague; indefinite; lax in signification; as, a loose and general expression.
(a.) Common to many, or the greatest number; widely spread; prevalent; extensive, though not universal; as, a general opinion; a general custom.
(a.) Having a relation to all; common to the whole; as, Adam, our general sire.
(a.) As a whole; in gross; for the most part.
(a.) Usual; common, on most occasions; as, his general habit or method.
(a.) The whole; the total; that which comprehends or relates to all, or the chief part; -- opposed to particular.
(a.) One of the chief military officers of a government or country; the commander of an army, of a body of men not less than a brigade. In European armies, the highest military rank next below field marshal.
(a.) The roll of the drum which calls the troops together; as, to beat the general.
(a.) The chief of an order of monks, or of all the houses or congregations under the same rule.
(a.) The public; the people; the vulgar.
Example Sentences:
(1) The generally accepted hypothesis is a coronary spasm but a direct cardiotoxicity of 5-FU cannot be.
(2) However, medicines have an important part to play, and it is now generally agreed that for the very poor populations medicines should be restricted to those on an 'essential drugs list' and should be made available as cheaply as possible.
(3) No differences between the two substances were observed with respect to side effects and general tolerability.
(4) It has been generally believed that the ligand-binding of steroid hormone receptors triggers an allosteric change in receptor structure, manifested by an increased affinity of the receptor for DNA in vitro and nuclear target elements in vivo, as monitored by nuclear translocation.
(5) The Cole-Moore effect, which was found here only under a specific set of conditions, thus may be a special case rather than the general property of the membrane.
(6) Neuroleptics (chlorpromazine, reserpine and haloperidol) had not such an influence, though they somewhat increased the general activity of the animals.
(7) Even though attempts to generalize the data from childbearing women to women of childbearing age have an inherent conservative bias, the results of our study suggest that 988 women (95% CI 713 to 1336) aged 15 to 44 years in Quebec had HIV infection in 1989.
(8) A subsample of patients scoring over the recommended threshold (five or above) on the general health questionnaire were interviewed by the psychiatrist to compare the case detection of the general practitioner, an independent psychiatric assessment and the 28-item general health questionnaire at two different cut-off scores.
(9) Size analysis of the solubilized IgA IP employing sucrose density gradient ultracentrifugation, indicated that these were heterogeneous, with a size generally larger than 19 S.
(10) In general, the concentrations measured by bioassay were higher than those by HPLC.
(11) Issues such as healthcare and the NHS, food banks, energy and the general cost of living were conspicuous by their absence.
(12) These findings suggest that clonidine transdermal disks lower blood pressure in hypertensive patients, but produce local skin lesions and general side effects.
(13) Augmentation of transformation response was generally not seen at 40 degrees C; incubation at that temperature was associated with decreased cellular viability.
(14) When compared with self-reported exposures, the sensitivity of both job-exposure matrices was low (on average, below 0.51), while the specificity was generally high (on average, above 0.90).
(15) 2009 Visits the US for first time to address the UN general assembly.
(16) UN internal investigators delivered a report to the then secretary general, Kofi Annan, but it was not published.
(17) Those without sperm, or with cloudy fluid, will require vasoepididymostomy under general or epidural anesthesia, which takes 4-6 hr.
(18) Ferrocene derivatives, in general, show a degree of versatility, coupling the electron-transfer reactions of many enzymes.
(19) Increased iron levels in basal ganglia were generally associated with normal or elevated levels of ferritin immunoreactivity, for example, the substantia nigra in PSP and possibly MSA, and in putamen in MSA.
(20) Other recommendations for immediate action included a review of the Nursing and Midwifery Council and the General Medical Council for doctors, with possible changes to their structures; the possible transfer of powers to launch criminal prosecutions for care scandals from the Health and Safety Executive to the Care Quality Council; and a new inspection regime, which would focus more closely on how clean, safe and caring hospitals were.