(a.) Preceding all others of a series or kind; the ordinal of one; earliest; as, the first day of a month; the first year of a reign.
(a.) Foremost; in front of, or in advance of, all others.
(a.) Most eminent or exalted; most excellent; chief; highest; as, Demosthenes was the first orator of Greece.
(adv.) Before any other person or thing in time, space, rank, etc.; -- much used in composition with adjectives and participles.
(n.) The upper part of a duet, trio, etc., either vocal or instrumental; -- so called because it generally expresses the air, and has a preeminence in the combined effect.
Example Sentences:
(1) First results let us assume that clinically silent TIAs also (in analogy to clinically silent brain infarctions) could be detected and located.
(2) Here we report that sperm from psr males fertilizes eggs, but that the paternal chromosomes are subsequently condensed into a chromatin mass before the first mitotic division of the egg and do not participate in further divisions.
(3) However, when first trimester specimens were analyzed, the direct-product measurements were significantly larger than the corresponding 3H2O assay results.
(4) In Patient 2 they were at first paroxysmal and unformed, with more prolonged metamorphopsia; later there appeared to be palinoptic formed images, possibly postictal in nature.
(5) Van Persie's knee injury meant that Mata could work in tandem with the delightfully nimble Kagawa, starting for the first time since 22 January.
(6) These studies led to the following conclusions: (a) all the prominent NHP which remain bound to DNA are also present in somewhat similar proportions in the saline-EDTA, Tris, and 0.35 M NaCl washes of nuclei; (b) a protein comigrating with actin is prominent in the first saline-EDTA wash of nuclei, but present as only a minor band in the subsequent washes and on washed chromatin; (c) the presence of nuclear matrix proteins in all the nuclear washes and cytosol indicates that these proteins are distributed throughout the cell; (d) a histone-binding protein (J2) analogous to the HMG1 protein of K. V. Shooter, G.H.
(7) The issue of the Schizophrenia Bulletin is devoted to articles representing this full range of conceptual and empirical work on first-episode psychosis.
(8) We conclude that first-transit and blood-pool techniques are equally accurate methods for determining EF when the time-activity method of analysis is employed.
(9) Oculomotor paresis with cyclic spasms is a rare syndrome, usually noticeable at birth or developing during the first year of life.
(10) In early 2000, during the first months of Vladimir Putin’s presidency, Babitsky was kidnapped by Russian forces and disappeared for many weeks.
(11) The Frenchman’s 65th-minute goal was a fifth for United and redemptive after he conceded the penalty from which CSKA Moscow took a first-half lead.
(12) The intrauterine mean active pressure (MAP) in the nulliparous group was 1.51 kPa (SD 0.45) in the first stage and 2.71 kPa (SD 0.77) in the second stage.
(13) For the first time it was organized on the basis of population.
(14) Immunocompetence was also evident when the cells from thymectomized donors were first incubated with thymus extract for 1 hr and subsequently tested for reactivity.
(15) gamma-Aminobutyric acid (GABA) and glutamate release from the treated side was higher than the control value during the first 2-3 h, a result indicating an important role of glial cells in the inactivation of released transmitter.
(16) The results of the evaluation confirm that most problems seen by first level medical personnel in developing countries are simple, repetitive, and treatable at home or by a paramedical worker with a few safe, essential drugs, thus avoiding unnecessary visits to a doctor.
(17) Complementarity determining regions (CDR) are conserved to different extents, with the first CDR region in all family members being among the most conserved segments of the molecule.
(18) Despite of the increasing diagnostic importance of the direct determination of the parathormone which is at first available only in special institutions in these cases methodical problems play a less important part than the still not infrequent appearing misunderstanding of the adequate basic disease.
(19) The present findings indicate that the deafferented [or isolated] hypothalamus remains neuronally isolated from the environment if the operation is carried out later than the end of the first week of life.
(20) Amino acid sequence analysis showed that both peaks had identical N-terminal sequences through the first 28 residues.
Impediment
Definition:
(n.) That which impedes or hinders progress, motion, activity, or effect.
(v. t.) To impede.
Example Sentences:
(1) Impediments to the necessary growth of this subspecialty for the needs of clinical practice and research are outlined and criteria for certification are reviewed.
(2) An understanding of the possible psychologic impediments to weight loss can promote improved therapeutic intervention for the obese patient.
(3) The results suggest that chronic sunlight exposure may be associated with an impediment to normal maturation of human dermal collagen resulting in tenuous amount of HHL.
(4) In order to achieve palatal closure with the least possible impediment to maxillary growth, the two-stage repair seems to be the best procedure in our hands.
(5) Causes of these impediments to maintaining nutritional status are discussed, and suggestions to overcome them are given.
(6) The data are consistent with the hypothesis that there is a sequential increasing impediment of the programmed cascade for downstream heavy chain constant region gene rearrangements.
(7) Lack of reproducibility is a severe impediment of both current conventional and kinetic methods in the prognosis of gliomas.
(8) These organizations can greatly reduce the logistic impediments to evaluating EMS care and initiating improvements.
(9) Changes in the evaluation protocol could preclude existing impediments to provision of information and patient autonomy; however, certain intrapsychic issues must be recognized as ongoing clinical realities to be addressed as the doctrine of informed consent continues to evolve.
(10) This survey shows that the use of nondiagnostic mammography is still less than optimal, and identifies impediments to screening that need to be addressed in cancer control planning efforts.
(11) The most frequently listed impediments included patients' advanced age or fragility, inadequate health insurance, and excess travel distance.
(12) Major issues identified include operational specificity, mislabelling of procedures, relative contributions of components in multi-faceted treatment packages, and impediments to systematic replication.
(13) The clinics of a single university hospital center were observed to determine a practical rationale for and impediments to implementing a medical care evaluation program.
(14) Accurate assessment and effective response is rendered difficult due to underrepresentation or denial by the patient and countertransference impediments to recognition and limit setting by the therapist.
(15) One impediment to such a study is the absence of any identified gene whose transcription is directly dependent on the receptor-hormone complex.
(16) But, according to Ruddick, the state council is a “gerrymander”, with factional leaders creating new “on-paper” branches that meet at most once a year in order to elect a delegate to state council and keep hold of “the numbers” – presenting Liberal reformers with exactly the same structural impediment to change as is faced by Labor.
(17) Conroy said the Minchin protocol was “merely an administrative policy adopted by the Department of Finance” which was “no impediment to a police investigation into Ms Bishop’s conduct”.
(18) A significant impediment in determining the relative contribution of whole blood viscosity to the pathogenesis of cardiovascular and cerebrovascular disease has been the lack of an uncomplicated method to measure whole blood viscosity.
(19) However, the lack of data on the forms of chromium-absorption from foods by the gastro-intestinal tract, and our concomitant inability to obtain an accurate assessment of the daily mobile pool of metabolically active chromium in the human body continues to be an impediment in assessing the overall impact of chromium nutrition.
(20) The results of this study indicated that the use of a nonresorbable hydroxylapatite for grafting resulted in impediment of tooth eruption and distortion of crown development.