(a.) Preceding all others of a series or kind; the ordinal of one; earliest; as, the first day of a month; the first year of a reign.
(a.) Foremost; in front of, or in advance of, all others.
(a.) Most eminent or exalted; most excellent; chief; highest; as, Demosthenes was the first orator of Greece.
(adv.) Before any other person or thing in time, space, rank, etc.; -- much used in composition with adjectives and participles.
(n.) The upper part of a duet, trio, etc., either vocal or instrumental; -- so called because it generally expresses the air, and has a preeminence in the combined effect.
Example Sentences:
(1) First results let us assume that clinically silent TIAs also (in analogy to clinically silent brain infarctions) could be detected and located.
(2) Here we report that sperm from psr males fertilizes eggs, but that the paternal chromosomes are subsequently condensed into a chromatin mass before the first mitotic division of the egg and do not participate in further divisions.
(3) However, when first trimester specimens were analyzed, the direct-product measurements were significantly larger than the corresponding 3H2O assay results.
(4) In Patient 2 they were at first paroxysmal and unformed, with more prolonged metamorphopsia; later there appeared to be palinoptic formed images, possibly postictal in nature.
(5) Van Persie's knee injury meant that Mata could work in tandem with the delightfully nimble Kagawa, starting for the first time since 22 January.
(6) These studies led to the following conclusions: (a) all the prominent NHP which remain bound to DNA are also present in somewhat similar proportions in the saline-EDTA, Tris, and 0.35 M NaCl washes of nuclei; (b) a protein comigrating with actin is prominent in the first saline-EDTA wash of nuclei, but present as only a minor band in the subsequent washes and on washed chromatin; (c) the presence of nuclear matrix proteins in all the nuclear washes and cytosol indicates that these proteins are distributed throughout the cell; (d) a histone-binding protein (J2) analogous to the HMG1 protein of K. V. Shooter, G.H.
(7) The issue of the Schizophrenia Bulletin is devoted to articles representing this full range of conceptual and empirical work on first-episode psychosis.
(8) We conclude that first-transit and blood-pool techniques are equally accurate methods for determining EF when the time-activity method of analysis is employed.
(9) Oculomotor paresis with cyclic spasms is a rare syndrome, usually noticeable at birth or developing during the first year of life.
(10) In early 2000, during the first months of Vladimir Putin’s presidency, Babitsky was kidnapped by Russian forces and disappeared for many weeks.
(11) The Frenchman’s 65th-minute goal was a fifth for United and redemptive after he conceded the penalty from which CSKA Moscow took a first-half lead.
(12) The intrauterine mean active pressure (MAP) in the nulliparous group was 1.51 kPa (SD 0.45) in the first stage and 2.71 kPa (SD 0.77) in the second stage.
(13) For the first time it was organized on the basis of population.
(14) Immunocompetence was also evident when the cells from thymectomized donors were first incubated with thymus extract for 1 hr and subsequently tested for reactivity.
(15) gamma-Aminobutyric acid (GABA) and glutamate release from the treated side was higher than the control value during the first 2-3 h, a result indicating an important role of glial cells in the inactivation of released transmitter.
(16) The results of the evaluation confirm that most problems seen by first level medical personnel in developing countries are simple, repetitive, and treatable at home or by a paramedical worker with a few safe, essential drugs, thus avoiding unnecessary visits to a doctor.
(17) Complementarity determining regions (CDR) are conserved to different extents, with the first CDR region in all family members being among the most conserved segments of the molecule.
(18) Despite of the increasing diagnostic importance of the direct determination of the parathormone which is at first available only in special institutions in these cases methodical problems play a less important part than the still not infrequent appearing misunderstanding of the adequate basic disease.
(19) The present findings indicate that the deafferented [or isolated] hypothalamus remains neuronally isolated from the environment if the operation is carried out later than the end of the first week of life.
(20) Amino acid sequence analysis showed that both peaks had identical N-terminal sequences through the first 28 residues.
Opening
Definition:
(p. pr. & vb. n.) of Open
(n.) The act or process of opening; a beginning; commencement; first appearance; as, the opening of a speech.
(n.) A place which is open; a breach; an aperture; a gap; cleft, or hole.
(n.) Hence: A vacant place; an opportunity; as, an opening for business.
(n.) A thinly wooded space, without undergrowth, in the midst of a forest; as, oak openings.
Example Sentences:
(1) says Gregg Wallace opening the new series of Celebrity MasterChef (Mon-Fri, 2.15pm, BBC1).
(2) Open field behaviors and isolation-induced aggression were reduced by anxiolytics, at doses which may be within the sedative-hypnotic range.
(3) His son, Karim Makarius, opened the gallery to display some of the legacy bequeathed to him by his father in 2009, as well as the work of other Argentine photographers and artists – currently images by contemporary photographer Facundo de Zuviria are also on show.
(4) Blatter requires a two-thirds majority of the 209 voters to triumph in the opening round, with a simple majority required if it goes to a second round.
(5) Clonazepam was added to the treatment of patients with poorly controlled epilepsy in a double-blind trial and an open trial.
(6) By hybridization studies, three plasmids in two forms (open circular and supercoiled) were detected in the strain A24.
(7) It is the only fully-fledged casino to open in the region, outside Lebanon.
(8) Sixty-six patients were followed for 12 months in an open safety study.
(9) The PUP founder made the comments at a voters’ forum and press conference during an open day held at his Palmer Coolum Resort, where he invited the electorate to see his giant robotic dinosaur park, memorabilia including his car collection and a concert by Dean Vegas, an Elvis impersonator.
(10) The purpose of the present study was to analyze the effects of cromakalim (BRL 34915), a potent drug from a new class of drugs characterized as "K+ channel openers", on the electrical activity of human skeletal muscle.
(11) An opening wedge osteotomy is then directed posterior-dorsal to anterior-plantar, to effectively plantarflex the posterior aspect of the calcaneus.
(12) … or a theatre and concert hall There are a total of 16 ghost stations on the Paris metro; stops that were closed or never opened.
(13) The decline in the frequency of serious complications was primarily due to a decrease in the proportion of patients with open fractures treated with plate osteosynthesis from nearly 50% to 19%.
(14) At 100 microM-ACh the apparent open time became shorter probably due to channel blockade by ACh molecules.
(15) 'The French see it as an open and shut case,' says a Paris-based diplomat.
(16) The White House denied there had been an agreement, but said it was open in principle to such negotations.
(17) The following model is suggested: exogenous ATP interacts with a membrane receptor in the presence of Ca2+, a cascade of events occurs which mobilizes intracellular calcium, thereby increasing the cytosolic free Ca2+ concentration which consequently opens the calcium-activated K+ channels, which then leads to a change in membrane potential.
(18) The data indicate greater legitimacy and openness in discussing holocaust-related issues in the homes of ex-partisans than in the homes of ex-prisoners in concentration camps.
(19) He also plans to build a processing facility where tourists can gain firsthand experience of the fisheries industry, and to open a restaurant.
(20) He had been just asked to open their new town hall, in the hope he might donate a Shakespeare statue.