(a.) Preceding all others of a series or kind; the ordinal of one; earliest; as, the first day of a month; the first year of a reign.
(a.) Foremost; in front of, or in advance of, all others.
(a.) Most eminent or exalted; most excellent; chief; highest; as, Demosthenes was the first orator of Greece.
(adv.) Before any other person or thing in time, space, rank, etc.; -- much used in composition with adjectives and participles.
(n.) The upper part of a duet, trio, etc., either vocal or instrumental; -- so called because it generally expresses the air, and has a preeminence in the combined effect.
Example Sentences:
(1) First results let us assume that clinically silent TIAs also (in analogy to clinically silent brain infarctions) could be detected and located.
(2) Here we report that sperm from psr males fertilizes eggs, but that the paternal chromosomes are subsequently condensed into a chromatin mass before the first mitotic division of the egg and do not participate in further divisions.
(3) However, when first trimester specimens were analyzed, the direct-product measurements were significantly larger than the corresponding 3H2O assay results.
(4) In Patient 2 they were at first paroxysmal and unformed, with more prolonged metamorphopsia; later there appeared to be palinoptic formed images, possibly postictal in nature.
(5) Van Persie's knee injury meant that Mata could work in tandem with the delightfully nimble Kagawa, starting for the first time since 22 January.
(6) These studies led to the following conclusions: (a) all the prominent NHP which remain bound to DNA are also present in somewhat similar proportions in the saline-EDTA, Tris, and 0.35 M NaCl washes of nuclei; (b) a protein comigrating with actin is prominent in the first saline-EDTA wash of nuclei, but present as only a minor band in the subsequent washes and on washed chromatin; (c) the presence of nuclear matrix proteins in all the nuclear washes and cytosol indicates that these proteins are distributed throughout the cell; (d) a histone-binding protein (J2) analogous to the HMG1 protein of K. V. Shooter, G.H.
(7) The issue of the Schizophrenia Bulletin is devoted to articles representing this full range of conceptual and empirical work on first-episode psychosis.
(8) We conclude that first-transit and blood-pool techniques are equally accurate methods for determining EF when the time-activity method of analysis is employed.
(9) Oculomotor paresis with cyclic spasms is a rare syndrome, usually noticeable at birth or developing during the first year of life.
(10) In early 2000, during the first months of Vladimir Putin’s presidency, Babitsky was kidnapped by Russian forces and disappeared for many weeks.
(11) The Frenchman’s 65th-minute goal was a fifth for United and redemptive after he conceded the penalty from which CSKA Moscow took a first-half lead.
(12) The intrauterine mean active pressure (MAP) in the nulliparous group was 1.51 kPa (SD 0.45) in the first stage and 2.71 kPa (SD 0.77) in the second stage.
(13) For the first time it was organized on the basis of population.
(14) Immunocompetence was also evident when the cells from thymectomized donors were first incubated with thymus extract for 1 hr and subsequently tested for reactivity.
(15) gamma-Aminobutyric acid (GABA) and glutamate release from the treated side was higher than the control value during the first 2-3 h, a result indicating an important role of glial cells in the inactivation of released transmitter.
(16) The results of the evaluation confirm that most problems seen by first level medical personnel in developing countries are simple, repetitive, and treatable at home or by a paramedical worker with a few safe, essential drugs, thus avoiding unnecessary visits to a doctor.
(17) Complementarity determining regions (CDR) are conserved to different extents, with the first CDR region in all family members being among the most conserved segments of the molecule.
(18) Despite of the increasing diagnostic importance of the direct determination of the parathormone which is at first available only in special institutions in these cases methodical problems play a less important part than the still not infrequent appearing misunderstanding of the adequate basic disease.
(19) The present findings indicate that the deafferented [or isolated] hypothalamus remains neuronally isolated from the environment if the operation is carried out later than the end of the first week of life.
(20) Amino acid sequence analysis showed that both peaks had identical N-terminal sequences through the first 28 residues.
Utmost
Definition:
(a.) Situated at the farthest point or extremity; farthest out; most distant; extreme; as, the utmost limits of the land; the utmost extent of human knowledge.
(a.) Being in the greatest or highest degree, quantity, number, or the like; greatest; as, the utmost assiduity; the utmost harmony; the utmost misery or happiness.
(n.) The most that can be; the farthest limit; the greatest power, degree, or effort; as, he has done his utmost; try your utmost.
Example Sentences:
(1) Differentiation between these two types of lesions is of utmost importance since the surgical approach will be different.
(2) In order to achieve guineaworm eradication in 1990s, the Guineaworm Eradication Programme (GWEP) should operate with utmost efficiency; and needs to be concurrently evaluated for timely corrective measures.
(3) The pH of the extraction buffer was of the utmost importance, since it was demonstrated that a pH greater than 5 would give rise to false signals.
(4) Whereas live Toxoplasma "vaccines" may be effective in sheep and goats, the eventual preparation of a killed vaccine capable of inducing long-term protection is of the utmost importance.
(5) Despite advantages and technological advances in the techniques of dental casts and ceramics attachment to metal, plastic materials for crown and bridge facetting are still of utmost importance for prosthetic procedures.
(6) * * * Stalker, meanwhile, having made his decision, pursued Tape 042 with the utmost vigour.
(7) Early recognition of the major peroxisomal disorders in which functional peroxisomes are virtually absent, leading to a generalised impairment of peroxisomal functions, is of utmost importance, as this will enable the prenatal diagnosis of these severe diseases in future pregnancies.
(8) It is incumbent on the US, Britain and France to do their utmost to help the country win the peace.
(9) We conclude that the stimulation of Pk-C is of utmost importance for OL regeneration.
(10) However, it is of utmost importance that the institutes in "Eastern Europe" establish these standards as soon as possible in order to be competitive and to be able to join research-projects with "Western" universities - a necessary source of income.
(11) A consultant knowledgeable in the problems of the spinal cord injured can be of utmost benefit especially in the labor and delivery process.
(12) Intubation, artificial ventilation, fluid administration (electrolyte-solution) are of utmost importance for their survival and to reduce the frequency of major complications.
(13) As such, we treat any such allegations with the utmost seriousness and we will be contacting Jess to offer to discuss her concerns in full.” Sutton, in his own statement, said: “I wholeheartedly deny that I said or did anything other than act with complete professionalism in my dealings with Jess.
(14) Incidence of renal hydatid cyst is rare and its diagnosis should be made with the utmost care and after subjecting the patient to intensive investigations to exclude other pathologies.
(15) Both numbering systems initiate at the utmost 5' terminus of mRNA synthesis; this 5' initiator nucleotide is assigned 1.
(16) He fulfilled a difficult role in a progressive and compassionate way … he has done his utmost to transform the CPS's record on rape and domestic violence, delivering improved conviction rates for both.
(17) This is of the utmost importance, both epidemiologically and from the individual patient's point of view, and is a prerequisite in preventing the spread of HIV infection.
(18) This may be partly due to excessive patient fear according to the general belief that the heart is the utmost important part of life.
(19) Vaginal scanning of the ovaries and the uterus is a diagnostic and monitoring tool of utmost importance in assisted conception.
(20) In severe cases where hemorrhages play so large a role, albeit infrequently, the specific action of iron in interference with coagulation mechanisms is of the utmost importance.