What's the difference between fixed and frozen?

Fixed


Definition:

  • (imp. & p. p.) of Fix
  • (a.) Securely placed or fastened; settled; established; firm; imovable; unalterable.
  • (a.) Stable; non-volatile.

Example Sentences:

  • (1) The catheter must be meticulously fixed to the skin to avoid its movement.
  • (2) The binding properties of formalin-fixed amelanotic melanoma cells were not identical to those of endothelial or unfixed target cells.
  • (3) On the basis of 180 interventions, they describe in detail the use of fibrin glue in myringo- and tympanoplasty for correct fixing of grafts.
  • (4) Theresa May signals support for UK-EU membership deal Read more Faull’s fix, largely accepted by Britain, also ties the hands of national governments.
  • (5) According to the finite element analysis, the design bases of fixed restorations applied in the teeth accompanied with the absorption of the alveolar bone were preferred.
  • (6) At a fixed concentration of nucleotide the effectiveness of elution was proportional to the charge on the eluting molecule.
  • (7) This suggests that molars do not maintain a fixed relationship to incisors over time, and extreme care must be taken to standardize an experiment to a specific body weight when using this method.
  • (8) Using an antibody to the nerve growth factor receptor (NGFR), we examined dendritic reticulum cells (DRCs) immunohistochemically in 62 formalin-fixed, paraffin-embedded lymph nodes from patients with reactive follicular hyperplasia or with various types of lymphoma.
  • (9) Females were killed at various times after the onset of mating or artificial insemination, oviducts were fixed and sectioned serially, and spermatozoa were counted individually as to their location in the oviduct.
  • (10) Rigidly fixing the pubic symphysis stiffened the model and resulted in principal stress patterns that did not reflect trabecular density or orientations as well as those of the deformable pubic symphysis model.
  • (11) Using a monoclonal antibody against dopamine and a rabbit antiserum against serotonin, 5-methoxytryptamine or tryptamine, we were able to achieve the simultaneous localization of two amines in glutaraldehyde-fixed sections of rat dorsal raphe nuclei.
  • (12) In one series of experiments, the animals were not treated before the tissues were conventionally fixed; in another, anesthetized animals were administered horseradish peroxidase 20 min before the tissues were fixed.
  • (13) Since all human cadaveric tissue is fixed whilst on the skeleton, we may assume that shrinkage of the muscles in such specimens is negligible.
  • (14) Isolated outer hair cells from the organ of Corti of the guinea pig have been shown to change length in response to a mechanical stimulus in the form of a tone burst at a fixed frequency of 200 Hz (Canlon et al., 1988).
  • (15) After permeabilization, with attendant partial extraction, the preparation can be fixed, then viewed by either deep-etch replication, or by high-resolution scanning electron microscopy, with structure of interest revealed in deep view.
  • (16) In contrast, in paraffin as well as in frozen sections of chick oviduct, fixed by immersion or in vapor, PR was exclusively nuclear, including in the absence of progesterone, and the intensity of immunostaining was not modified by progesterone treatment.
  • (17) Filipin-induced lesions in glutaraldehyde-fixed parasites indicated higher levels of beta-hydroxysterols in the amastigote than in the promastigote plasma membrane, and in the promastigote flagellar membrane than in the body membrane.
  • (18) Using a silver staining technique (AgNOR technique), we have investigated the nucleolar organizer-associated proteins (NORs) in formalin-fixed paraffin embedded conjunctival specimens of 15 intraepithelial squamous carcinomas, 10 hyperplastic-dysplastic samples and 10 control epithelial fragments; the mean number of intranuclear black dots was determined for each case.
  • (19) Radiologists may encounter patients with fixed dental prostheses that may produce image distortion on MRI scans of the face and jaw.
  • (20) A rubber cuff was fixed on the metal cylinder and let an opening of 8 cm, simulating the cervix uteri.

Frozen


Definition:

  • (p. p.) of Freeze
  • (a.) Congealed with cold; affected by freezing; as, a frozen brook.
  • (a.) Subject to frost, or to long and severe cold; chilly; as, the frozen north; the frozen zones.
  • (a.) Cold-hearted; unsympathetic; unyielding.

Example Sentences:

  • (1) Limited biopsic retroperitoneal lymphnode dissection subsequently extended following the result of the frozen section histology.
  • (2) To selectively stain polyanionic macromolecules of growth plate cartilage and to prevent artifacts induced by aqueous fixation, proximal tibial growth plates were excised from rats, slam-frozen, and freeze-substituted in 100% methanol containing the cationic dye Alcian blue.
  • (3) Since the employment of microwave energy for defrosting biological tissues and for microwave-aided diagnosis in cryosurgery is very promising, the problem of ensuring the match between the contact antennas (applicators) and the frozen biological object has become a pressing one.
  • (4) In contrast, in paraffin as well as in frozen sections of chick oviduct, fixed by immersion or in vapor, PR was exclusively nuclear, including in the absence of progesterone, and the intensity of immunostaining was not modified by progesterone treatment.
  • (5) In this study 470 bitches were inseminated; 405 with fresh semen into the cranial vagina and 65 with frozen semen transcervically into the uterus.
  • (6) For frozen noises, the same sample of noise was presented throughout a block of 50 trials; for the random noises, different samples of noise were used in each interval of the trials.
  • (7) Two modalities for long-term treatment are accepted as useful in these children: oral anticoagulant therapy or protein C replacement (fresh frozen plasma or prothrombin complex concentrate).
  • (8) The linear electric field shift in paramagnetic resonance has, for the first time, been observed in frozen solutions.
  • (9) Frozen brain specimens from patients with multiple sclerosis (MS) and other neurologic diseases were analyzed using immunocytochemical techniques for the presence of TNF.
  • (10) For example, Asda lifted the price of frozen pizza from £1.50 to £2 as a “two for £3” offer appeared – and dropped the price again when the offer concluded.
  • (11) Once frozen the specimen must be handled in such a way that it becomes vacuum compatible for subsequent analysis.
  • (12) We have made an electron microscopic study of replicas of frozen-fractured BHK21 cells (from tissue culture) and of brown fat cells of newborn mice.
  • (13) The results showed immunostaining to function equally well on frozen and routine sections, and to be superior to Alcian Blue and PAS with regard to morphological detail.
  • (14) IFN-beta induced more enhanced NK cytotoxicity of normal lymphocytes when frozen tumor target cells were cultured for 4-5 days in the medium, or when these cells were treated with Vibrio cholerae neuraminidase (VCN).
  • (15) The values of the energy level distributions in crystals obtained from the measurements and analysis reported here are compared with those obtained by a different method for the same protein complex in frozen solution.
  • (16) Binding of [125I]-labelled ifenprodil, a non-competitive N-methyl-D-aspartate (NMDA) antagonist acting at the polyamine domain, was studied in washed, frozen-thawed synaptic membranes.
  • (17) Steroid hormone receptors were studied in 45 patients with primary, recurrent, or metastatic ovarian cancer in cryostat-frozen sections and imprint preparations.
  • (18) Optimal staining of antigen rich tissue, such as frozen sections, with the peroxidase antiperoxidase method required low antiserum concentrations apparently to minimize the binding of both antigen-binding fragments of the bridging antibody to the tissue bound antiserum.
  • (19) These observations may be important in the development of laboratory protocols for freezing and clinical protocols for using frozen-thawed sperm.
  • (20) Interpretation of frozen sections of needle biopsies of breast lesions is reliable when performed by experienced surgeons and handled and interpreted by experienced pathologists.