(n.) The fleshy or muscular part of the side of an animal, between the ribs and the hip. See Illust. of Beef.
(n.) The side of an army, or of any division of an army, as of a brigade, regiment, or battalion; the extreme right or left; as, to attack an enemy in flank is to attack him on the side.
(n.) That part of a bastion which reaches from the curtain to the face, and defends the curtain, the flank and face of the opposite bastion; any part of a work defending another by a fire along the outside of its parapet.
(n.) The side of any building.
(n.) That part of the acting surface of a gear wheel tooth that lies within the pitch line.
(v. t.) To stand at the flank or side of; to border upon.
(v. t.) To overlook or command the flank of; to secure or guard the flank of; to pass around or turn the flank of; to attack, or threaten to attack; the flank of.
(v. i.) To border; to touch.
(v. i.) To be posted on the side.
Example Sentences:
(1) In dorsoventral (DV) reversed wings at both shoulder or flank level, the motor axons do not alter their course as they enter the graft.
(2) Three overlapping clones, spanning a total of 19 kb of the human SC gene, including 3 kb of the 5' flanking region, were characterized.
(3) Thus, human bronchial epithelial cells can express the IL-8 gene, with expression in response to the inflammatory mediator TNF regulated mainly at the transcriptional level, and with elements within the 5'-flanking region of the gene that are directly or indirectly modulated by the TNF signal.
(4) Peptides from this region bind to actin, act as mixed inhibitors of the actin-stimulated S1 Mg2(+)-ATPase, and influence the contractile force developed in skinned fibres, whereas peptides flanking this sequence are without effect in our test systems.
(5) We present the nucleotide sequence of the galactokinase gene (galK) of Escherichia coli including its 5' and 3' flanking regions.
(6) Hypersensitive sites identified in the 3'-flanking region showed no change with T3 stimulation.
(7) Exons and flanking introns (greater than 14 kb) were sequenced to determine the structural organization of the gene.
(8) IS1106 has a length of 1137 bp and is flanked by 36bp inverted repeats.
(9) These results suggest that the Eco RI site in the flanking region of the 21-hydroxylase gene may be modified in adrenal cancer tissue, and that inadequate 21-hydroxylase is present in some forms of adrenal cancers.
(10) Our results indicate that provirus expression occurs by two different mechanisms: one provirus acquired a single base pair mutation in the retrovirus tRNA primer binding site, permitting provirus expression; expression of three proviruses was mediated by 5'-flanking DNA sequences.
(11) The sequences in the 5'-flanking region of the alpha- and beta-MYHC-encoding genes diverge extensively from one another, suggesting that expression of the alpha- and beta-MYHC genes is independently regulated.
(12) DNA sequence analysis of a 3.8-kb genomic piece allowed identification of (i) an open reading frame (ORF) with striking homology to the previously identified D. melanogaster ORF and (ii) conserved sequence elements of possible regulatory relevance within and flanking the second intron.
(13) To identify DNA sequences that were responsible for the high level of transcription of the gene for adipocyte P2 in vivo, we made a series of transgenic mice containing 168 base pairs (bp), 247 bp, 1.7 kilobases (kb), and 5.4 kb of 5' flanking sequence linked to the bacterial gene chloramphenicol acetyltransferase.
(14) Studies with substrate analogs selectively modified at the basic doublet indicated that the integrity of both basic amino acids is essential but that conformational parameters, probably governed by the amino acid sequences flanking the basic doublet, play an important role.
(15) A prospective study compared the diagnostic accuracy of sonography and excretory urography in determining the cause of acute flank pain in 61 patients.
(16) The regulatory region of the casein gene contains two different TATA signals flanking the duplication site in the promoter region.
(17) Each of the mice received 3 pieces of explants on the s.c. space in both of their flanks.
(18) The 1947 base pairs of 5' flanking sequence contains several putative regulatory elements including two adjacent Oct I binding elements, four glucocorticoid regulatory elements and a sequence very homologous to the previously described fat specific element at--1402 nt.
(19) In earlier studies with the SV40-transformed hamster cell line Elona two different types of DNA amplification could be identified: (i) Bidirectional overreplication of chromosomally integrated SV40 DNA expanding into the flanking cellular sequences ("onion skin" type) and (ii) highly efficient synthesis of extremely large head-to-tail concatemers containing exclusively SV40 DNA ("rolling circle" type).
(20) In addition, the transcriptional behaviour of this tRNALeuCUG gene in various in vitro systems is described and it seems that, although the gene is transcribed in all test systems, the very A + T-rich 5'-flanking sequence of this particular gene may be somewhat inhibitory to transcription in vitro.
Flask
Definition:
(n.) A small bottle-shaped vessel for holding fluids; as, a flask of oil or wine.
(n.) A narrow-necked vessel of metal or glass, used for various purposes; as of sheet metal, to carry gunpowder in; or of wrought iron, to contain quicksilver; or of glass, to heat water in, etc.
(n.) A bed in a gun carriage.
(n.) The wooden or iron frame which holds the sand, etc., forming the mold used in a foundry; it consists of two or more parts; viz., the cope or top; sometimes, the cheeks, or middle part; and the drag, or bottom part. When there are one or more cheeks, the flask is called a three part flask, four part flask, etc.
Example Sentences:
(1) Plaque size, appearance, and number were influenced by diluent, incubation temperature after nutrient overlay, centrifugation of inoculated tissue cultures, and number of host cells planted initially in each flask.
(2) In both media the DNA and protein content of cultures kept for 3-5 days in the presence of 80-800 nM Buserelin and 1 nM oestradiol were 8-27% lower than those of flasks cultured in the presence of oestradiol alone (P less than 0.05).
(3) The vacuum flask method of using boiling water to decontaminate soft contact lenses is better and less expensive than other ways of using moist heat and can be safely and effectively applied under most domestic circumstances.
(4) With 1-octanol-saturated buffers as mobile phases, a stable baseline (compared to 1-octanol adsorbed on silica) is obtained rapidly, and the log relative retention times are highly correlated with unit slope to log distribution or partition coefficients obtained from the classical shake-flask procedures.
(5) Bacterial and plasmid yields have been shown to be equal to or greater than those obtained using conventional shake flasks.
(6) The carbohydrate compounds of the mucus of flask cells in the kidney of claw-frogs (Xenopus laevis) were studied by gold marked lectins (WGA, RCA, L, LCA, HPA, PNA).
(7) Irradiated melanomas did not grow and did not attach to culture flasks, thus demonstrating that preenucleation irradiation alters the in vitro growth of melanoma cells.
(8) An orbital shaker was used to create a water current in 250-ml Erlenmeyer flasks containing the test larvae.
(9) The cuffed end of each tracheal tube was inserted into the neck of an empty flask, and the tube and flask were flushed with oxygen for 5 min before cuff inflation.
(10) Incubations were carried out in sealed flasks under oxygen concentrations ranging from 0.14 to 21% at 37 degrees.
(11) The reverse difference in the temperatures (higher temperature of the culture flasks) leads to the formation of the reverse pattern of the cell layer, with higher density corresponding to the holes.
(12) By the use of double-chamber tissue culture flasks, with the 2 cell populations separated by a cell impermeable membrane, it was found that T-T interaction does not require cell contact and is thus mediated by factor(s).
(13) Everyone knows that Father Christmas’s tipple of choice is brandy, so Santa, if you’re reading this, we recommend you pause in The Flask on Highgate West Hill for a quick snifter.
(14) The tumor specimens were minced into fragments approximately 1 mm in diameter and cultured in plastic culture flasks in RPMI 1640 medium supplemented with 10% heat-inactivated fetal calf serum (FCS) and 50% patients serum.
(15) Oxygen diffusion distance was measured in solid tumor "cubes" prepared by excising the tumor from the mouse and incubating 1-2 mm sided tumor cubes in spinner culture flasks with fluorescent drugs (AF-2 or DM113) which bind to hypoxic cells.
(16) The growth-promoting effect on haemopoietic cells seems to be independent of the number of marrow cells per culture flask initially inoculated into the cultures to establish the adherent cell layer.
(17) Cells were cultured in Roux flasks in HAM's F-12 medium, and the pH was varied with the final medium change.
(18) The procedure involved the transfer of heavy mold-form inocula to flasks that contained small volumes of brain heart infusion broth.
(19) We have recently shown that the semi-continuous cultivation of a mouse hybridoma line in spinner flasks, with a basal defined medium (BDM) devoid of serum and protein, increases the secretion of the immunoreactive monoclonal antibody (MAb) by a factor of ca.
(20) Cultured human adrenal cortical adenocarcinoma cells (SW-13) form a confluent monolayer of epithelial-like cells when seeded into culture flasks.