(superl.) Having an even and horizontal surface, or nearly so, without prominences or depressions; level without inclination; plane.
(superl.) Lying at full length, or spread out, upon the ground; level with the ground or earth; prostrate; as, to lie flat on the ground; hence, fallen; laid low; ruined; destroyed.
(superl.) Wanting relief; destitute of variety; without points of prominence and striking interest.
(superl.) Tasteless; stale; vapid; insipid; dead; as, fruit or drink flat to the taste.
(superl.) Unanimated; dull; uninteresting; without point or spirit; monotonous; as, a flat speech or composition.
(superl.) Lacking liveliness of commercial exchange and dealings; depressed; dull; as, the market is flat.
(superl.) Below the true pitch; hence, as applied to intervals, minor, or lower by a half step; as, a flat seventh; A flat.
(superl.) Not sharp or shrill; not acute; as, a flat sound.
(superl.) Sonant; vocal; -- applied to any one of the sonant or vocal consonants, as distinguished from a nonsonant (or sharp) consonant.
(adv.) In a flat manner; directly; flatly.
(adv.) Without allowance for accrued interest.
(n.) A level surface, without elevation, relief, or prominences; an extended plain; specifically, in the United States, a level tract along the along the banks of a river; as, the Mohawk Flats.
(n.) A level tract lying at little depth below the surface of water, or alternately covered and left bare by the tide; a shoal; a shallow; a strand.
(n.) Something broad and flat in form
(n.) A flat-bottomed boat, without keel, and of small draught.
(n.) A straw hat, broad-brimmed and low-crowned.
(n.) A car without a roof, the body of which is a platform without sides; a platform car.
(n.) A platform on wheel, upon which emblematic designs, etc., are carried in processions.
(n.) The flat part, or side, of anything; as, the broad side of a blade, as distinguished from its edge.
(n.) A floor, loft, or story in a building; especially, a floor of a house, which forms a complete residence in itself.
(n.) A horizontal vein or ore deposit auxiliary to a main vein; also, any horizontal portion of a vein not elsewhere horizontal.
(n.) A dull fellow; a simpleton; a numskull.
(n.) A character [/] before a note, indicating a tone which is a half step or semitone lower.
(n.) A homaloid space or extension.
(v. t.) To make flat; to flatten; to level.
(v. t.) To render dull, insipid, or spiritless; to depress.
(v. t.) To depress in tone, as a musical note; especially, to lower in pitch by half a tone.
(v. i.) To become flat, or flattened; to sink or fall to an even surface.
(v. i.) To fall form the pitch.
Example Sentences:
(1) Michael James, 52, from Tower Hamlets Three days after telling his landlord that the flat upstairs was a deathtrap, Michael James was handed an eviction notice.
(2) A tiny studio flat that has become a symbol of London's soaring property prices is to be investigated by planning, environmental health and fire safety authorities after the Guardian revealed details of its shoebox-like proportions.
(3) With the flat-fee system, drug charges are not recorded when the drug is dispensed by the pharmacy; data for charging doses are obtained directly from the MAR forms generated by the nursing staff.
(4) Taking into account the calculated volume and considering the triangular image as one face of the particle, it is suggested that eIF-3 has the shape of a flat triangular prism with a height of about 7 nm and the above-mentioned side-lengths.
(5) He gets Lyme disease , he dates indie girls and strippers; he lives in disused warehouses and crappy flats with weirded-out flatmates who want to set him on fire and buy the petrol to do so.
(6) The b-wave in the ERG was lacking and the EOG was flat.
(7) In north-west Copenhagen, among the quiet, graffiti-tagged streets of red-brick blocks and low-rise social housing bordering the multi-ethnic Nørrebro district, police continued to cordon off roads and search a flat near the spot where officers killed a man believed to be behind Denmark’s bloodiest attacks in over a decade.
(8) Distance running performance is slower on hilly race courses than flat courses even when the start and finish are at the same elevation, resulting in equal amounts of uphill and downhill running.
(9) In autumn, leaf-heaps composted themselves on sunken patios, and were shovelled up by irritated owners of basement flats.
(10) Here we present images of polydeoxyadenylate molecules aligned in parallel, with their bases lying flat on a surface of highly oriented pyrolytic graphite and with their charged phosphodiester backbones protruding upwards.
(11) All other broad-spectrum benzimidazole anthelmintics, regardless of substituent at the 2 position (methyl carbamate or thiazolyl group), are flat.
(12) We investigated the mechanism by which retinoic acid causes growth arrest and flat reversion of SSV-NRK, simian sarcoma virus-transformed normal rat kidney cells.
(13) When she speaks, it is in a quiet, clear voice that is middle-class but also flat and London-inflected enough to seem almost classless: it is the voice of the modern southern English professional.
(14) After about 3 weeks of culture, N-ethyl-N-nitrosourea-pretreated fetal rat brain cells showed focal proliferation of neural cells on an underlayer of flat, epithelioid cells.
(15) In order to determine an histological high-risk group, we chose cases with preneoplastic conditions (60 CAG, 10 biopsies of gastric remnants, 3 flat adenomas and 55 gastrectomies by cancer or ulcer).
(16) During inspiration, the velocity was greater and the shape of the flow profile throughout diastole tended to be flat.
(17) The following relationships were found: Round nuclei have higher rates of DNA synthesis than flat ones.
(18) The individual micelles are relatively flat, ring-shaped structures, the center offering space for one of the two bulky sugar chains of the saponins.
(19) Microinfusion of the selective 5-HT1A receptor agonist, 8-hydroxy-(di-N-propylamino)tetralin (8-OHDPAT), into the dorsal raphe nucleus (DRN) produced a marked behavioural hypoactivity and flat body posture.
(20) Don was racing the Dodge through the Bonneville Salt Flats , where Gary Gabelich had just (on 23 October) broken the land-speed record.
Rough
Definition:
(n.) Having inequalities, small ridges, or points, on the surface; not smooth or plain; as, a rough board; a rough stone; rough cloth.
(n.) Not level; having a broken surface; uneven; -- said of a piece of land, or of a road.
(n.) Not polished; uncut; -- said of a gem; as, a rough diamond.
(n.) Tossed in waves; boisterous; high; -- said of a sea or other piece of water.
(n.) Marked by coarseness; shaggy; ragged; disordered; -- said of dress, appearance, or the like; as, a rough coat.
(n.) Hence, figuratively, lacking refinement, gentleness, or polish.
(n.) Not courteous or kind; harsh; rude; uncivil; as, a rough temper.
(n.) Marked by severity or violence; harsh; hard; as, rough measures or actions.
(n.) Loud and hoarse; offensive to the ear; harsh; grating; -- said of sound, voice, and the like; as, a rough tone; rough numbers.
(n.) Austere; harsh to the taste; as, rough wine.
(n.) Tempestuous; boisterous; stormy; as, rough weather; a rough day.
(n.) Hastily or carelessly done; wanting finish; incomplete; as, a rough estimate; a rough draught.
(n.) Produced offhand.
(n.) Boisterous weather.
(n.) A rude fellow; a coarse bully; a rowdy.
(adv.) In a rough manner; rudely; roughly.
(v. t.) To render rough; to roughen.
(v. t.) To break in, as a horse, especially for military purposes.
(v. t.) To cut or make in a hasty, rough manner; -- with out; as, to rough out a carving, a sketch.
Example Sentences:
(1) By 24 hr, rough endoplasmic reticulum in thecal cells increased from 4.2 to 7% of cell volume, while the amount in granulosa cells increased from less than 3.5% to more than 10%; the quantity remained relatively constant in the theca but declined to prestimulation values in the granulosa layer.
(2) Thus, it appears that neuronal loss may account for up to roughly half of the striatal D2 receptor loss during aging.
(3) The cis isomer was retained longer in liver, particularly in mitochondria, but had low retention in that portion of the endoplasmic reticulum isolated as the rough membrane fraction.
(4) The results indicated that roughly 25% of patients treated in this way will become hypothyroid after 5 years and that 85% are cured (need no further therapy during the follow-up period) using a single dose of iodine-131.
(5) This heretogeneity occurred mainly as a progressive, decreasing gradient in the first half of this pathway, between the rough endoplasmic reticulum and the mi-cisternae of the Golgi apparatus.
(6) Electron microscopy revealed a well-developed rough endoplasmic reticulum, an enlarged Golgi apparatus and many highly electron-dense secretory granules resembling those of Clara cells.
(7) Four fractions enriched, respectively, in plasma membrane (PM), smooth endoplasmic reticulum (SER), rough endoplasmic reticulum (RER), and mitochondria were isolated from estrogen-dominated rat myometrium.
(8) For trials in which the target was present in the array, RT functions were roughly symmetric, the shortest RTs being for extreme distractor ratios, and the longest RTs being for arrays in which there were an equal number of each distractor type.
(9) Classic technics of digital image analysis and new algorithms were used to improve the contrast on the full image or a portion of it, contrast a skin lesion with statistical information deduced from another lesion, evaluate the shape of the lesion, the roughness of the surface, and the transition region from the lesion to the normal skin, and analyze a lesion from the chromatic point of view.
(10) Electron microscopic evaluation of microsomal fractions showed elements of the plasma membrane, including cilia and microvilli, as well as rough and smooth endoplasmic reticulum.
(11) The local guide led us down a rough, uneven pathway, talking as he went.
(12) It's the roughly $2bn in revenue grossed by his blockbuster movies, some of which he had to be talked into making.
(13) The interaction between PE and E-IgG involved the extension of micropseudopods toward adherent E-IgG, the formation of a linear uniform cap of roughly 200 A between opposing cell membranes, the ingestion of E-IgG by PE into a membrane-lined compartment, and the disintegration of the ingested ligand into membranous debris.
(14) Ultracentrifugally separated HDL2 and HDL3 roughly corresponded to HDL2e and HDL3e, respectively.
(15) The locations of these 15 insertion sites correlate well with the roughly estimated locations of five of the DNase I-hypersensitive subregions.
(16) The Lords will vote on three key amendments: • To exclude child benefit from the cap calculation (this would roughly halve the number of households affected).
(17) The unique structure we describe is a cytoplasmic organelle which, like annulate lamellae, is closely associated with the endoplasmic reticulum and is presumed to be related to the genesis of rough-surfaced endoplasmic reticulum in tumor cells.
(18) Besides the rough, wrinkled, and brown or black surface of the fingertips, microwrinkles of the epidermis occur on the skin ridges, which have so far not been described.
(19) Ultrastructural examination of noncartilaginous regions of the tumor demonstrated mesenchymal cells with features suggestive of cartilaginous differentiation, viz, scalloped cell membranes, sac-like distension of abundant rough endoplasmic reticulum, and a matrix containing fibrillary and finely granular material.
(20) That, roughly, was the theme of the Wednesday Play, Cathy Come Home, (BBC1) directed by Kenneth Loach, produced by Tony Garnett.