(1) Manic patients produced thought disorders that revealed both prominent combinatory thinking and intrusions of irrelevant ideas into the stream of discourse, usually with flippancy and humor.
(2) Apologies for the flippancy, but things have moved on a bit since the last coronation and United still do not appear to appreciate the seriousness of the new situation.
(3) The thought disorder of manic patients was extravagantly combinatory, usually with humor, flippancy, and playfulness.
(4) The force of this logic is as plain as the flippancy of the Cameron proposal for 27 sovereign nations to fall into line with what amounts to a party management plan.
(5) Underpinning the witty remarks and the textbook flippancy ("call me early, Goering dear, for I'm to be Queen of the May" was apparently Nancy's riposte to news of Diana and Unity's German adventures) though, was an absolute and obdurate self-belief; a self-possessed seriousness only partly disguised by sisterly teasing.
(6) Apologies for the flippancy but things have moved on a bit since the last coronation and United still do not appear to appreciate the seriousness of the new situation.
(7) He also knows when to skip the flippancies: he concedes that the scientific advances of the last 100 years now mean that it is possible to consider life in terms of physics and chemistry ("no life force, no spirit, no soul seems to be involved") and to see in the universe "a magnificence, and an intricate, elegant order far beyond anything our ancestors imagined."
(8) DJ Taylor summed up the Mitfords as “ witty remarks and textbook flippancy [underpinned by] an absolute and obdurate self-belief ”.
(9) It also encapsulates the essential flippancy of the Conservative approach, with the Lib Dems dragged haplessly along behind.
(10) This was when Whoopi Goldberg, discussing the case on a TV panel show, remarked that what happened was "not rape-rape" – something Geimer has tried to treat with the flippancy it deserves.
(11) Other remarks made by Johnson during his visit combined his usual flippancy with hyperbolic enthusiasm for Israel and patronising comments about “Arabs”, not least in his inaugural Winston Churchill speech in Jerusalem.
(12) It's the grubbiness of it, the apparent acceptability of the leer, that makes Page 3 so outdated, embodying as it does the "just a cheeky bit of perving" flippancy of 1970s seaside postcard.
Profound
Definition:
(a.) Descending far below the surface; opening or reaching to a great depth; deep.
(a.) Intellectually deep; entering far into subjects; reaching to the bottom of a matter, or of a branch of learning; thorough; as, a profound investigation or treatise; a profound scholar; profound wisdom.
(a.) Characterized by intensity; deeply felt; pervading; overmastering; far-reaching; strongly impressed; as, a profound sleep.
(a.) Bending low, exhibiting or expressing deep humility; lowly; submissive; as, a profound bow.
(n.) The deep; the sea; the ocean.
(n.) An abyss.
(v. t.) To cause to sink deeply; to cause to dive or penetrate far down.
(v. i.) To dive deeply; to penetrate.
Example Sentences:
(1) With profound blockade, the slope of the edrophonium dose-response relationship was significantly flatter (P less than 0.05) than that of neostigmine.
(2) Cadavers have a multitude of possible uses--from the harvesting of organs, to medical education, to automotive safety testing--and yet their actual utilization arouses profound aversion no matter how altruistic and beneficial the motivation.
(3) Our positive experiences with IMACS discussed above should be even more profound and profitable for the larger medical institutions.
(4) This study compares the effects of 60 minutes of ischemic arrest with profound topical hypothermia (10 dogs) on myocardial (1) blood flow and distribution (microspheres), (2) metabolism (oxygen and lactate), (3) water content (wet to dry weights), (4) compliance (intraventricular balloon), and (5) performance (isovolumetric function curves) with 180 minutes of cardiopulmonary bypass with the heart in the beating empty state (seven dogs).
(5) About one out of three profoundly deaf children has an autosomal recessive form of inherited deafness.
(6) This continuing influence of Nazi medicine raises profound questions for the epistemology and morality of medicine.
(7) However six equivocal studies were observed in profoundly jaundiced patients with bilirubin levels above 400 mumol l-1 due to difficulties in differentiating extrahepatic obstruction from severe intrahepatic cholestasis.
(8) After a 2-day incubation with IL-4, expression of IL-2R p55 was markedly induced, but expression of IL2-R p70-75 was profoundly suppressed in a dose-dependent manner.
(9) "For those people who are able to use the laws, the change is profound."
(10) Most striking finding was his difficulty in identifying common objects and colours along with a profound alexia.
(11) This BOA technique was used to test the hearing of 82 profoundly involved handicapped children.
(12) These tools will allow us to manipulate the mammalian immune response in a variety of different ways that will have a profound impact both on our understanding of immunology and on medicine in the future.
(13) Based on the fact that all hibernators, at their regulated minimal body temperature, display a uniform turnover rate, related to body weight, the hypothesis is developed that cold tolerance of mammals is generally limited by a common specific minimal metabolic rate, which larger organisms, because of their lower basal metabolism, already attain in less profound hypothermia.
(14) Insulin-like growth factor II (IGF-II) is present at high levels in fetal and early neonatal rat plasma, and decreases profoundly following birth.
(15) The reduction in level of activity and adverse changes in body composition caused by SCI have profound metabolic consequences that may influence the progression and severity of coronary artery disease.
(16) The case of a 32-year-old man who suffered a blow to his left supraorbital region and eyebrow in an automatic closing door is reported to draw attention to the uncommon but trivial nature of this injury which may result in profound visual loss.
(17) In the paper life-threatening diseases which may be accompanied by profound unconsciousness are explained from the laboratory-chemical point of view.
(18) However pneumonia to PC points to a poor prognosis because they are always associated with a profound deficit or cellular immunity.
(19) Thus, it is possible that the loss of these dendritic cells may contribute to the profound immunological abnormalities seen in AIDS.
(20) They produce a more profound effect on clinical and biochemical aspects of rheumatoid arthritis than do the aspirin-like non steroidals.