(v. t.) To clap or strike, as a bird its wings, a fish its tail, etc.; to flap.
(v. t.) To turn suddenly, as something broad and flat.
(v. i.) To strike about with something broad abd flat, as a fish with its tail, or a bird with its wings; to rise and fall; as, the brim of a hat flops.
(v. i.) To fall, sink, or throw one's self, heavily, clumsily, and unexpectedly on the ground.
(n.) Act of flopping.
Example Sentences:
(1) 3) Just as lipids do not flip-flop, proteins do not rotate across the membrane.
(2) And it was here, several years later, that I came looking for an answer to a question which has baffled many cynical film critics: how did a low-key prison drama, which was considered a box-office flop on its initial release, become one of the most popular movies of all time?
(3) The presence of the flip-flop phenomenon in an I-131 Hippuran renal study suggests the existence of some degree of collecting system obstruction that has persisted long enough to result in renal parenchymal damage.
(4) Peter Travers, film critic at Rolling Stone, offered a simpler explanation: "Why is The Lone Ranger such a huge flop at the box office?"
(5) Telomeres were generated from both arms of the substrate with equal efficiency, and contained the characteristic "flip" and "flop" sequence inversions observed in vivo.
(6) This value is similar to that obtained for the transbilayer "flip-flop" of phosphatidylcholine molecules in a similar system (Kornberg and McConnell, 1971).
(7) This suggests that generalizations on the kinetics of nonmediated flip-flop of membrane-intercalated amphiphiles may not be justified.
(8) Her agony and her rapture stay interior, and they flip-flop like nerves in this beautiful, grave black-and-white movie.
(9) The story of the transfer window is the story of a flip-flop by the English elite – the Premier League was initially the driving force behind the idea of a transfer window, but by the time it was introduced it was firmly in the "no" camp.
(10) He kept smiling, but he let his arm go limp, his hand flopping from the wrist in a clear signal of non-compliance.
(11) It is a plausible claim, judging by the cacophony of trumpets, cymbals, drums and violins erupting from classrooms, corridors and the courtyard: hundreds of children aged six to 19, some in trainers, others in flip-flops, individually and collectively making music.
(12) In April, Quentin Tarantino's revenge western Django Unchained was withdrawn from cinemas minutes into its first screening; it reopened a month later with three of the goriest minutes missing and flopped.
(13) Four models were proposed to analyze the experimental data: (A) two independent and nonequivalent subunits; (B) a single active subunit (subunits presenting absolute "half-of-the-sites reactivity"); (C) alternate functioning of the subunits (flip-flop mechanism); (D) random functioning of the subunits with half-of-the-sites reactivity.
(14) Pharmacokinetics of the depot antipsychotics are unclear and mainly depend on releasing from the depot site (according to a "flip-flop" model).
(15) Many people you talk to will label Twitter Music as a flop: its iPhone app flew high briefly in the App Store, then sank swiftly.
(16) The contrast with the relaxed Holland squad – spotted wandering around upmarket Sandton in flip-flops with their wives as they made their way to the final – was instructive.
(17) Another time I kissed this boy wearing flip-flops, and she said his toenails looked like quavers.
(18) We would love to continue to work with Gordon but it would be on a project-by-project basis.” Ramsay, said to be lining up a project for ITV , was among the C4 talent shoehorned into 2012’s reality flop Hotel GB, along with Gok Wan, Phil Spencer, Mary Portas (unlike Ramsay she remains on an exclusive C4 deal) and others.
(19) And I would have enough confidence in my argument to wait for events to vindicate it, rather than flopping around with each new set of figures.
(20) But Walt Disney has now warned that the film could instead go down as one of the year's biggest flops, predicting losses of almost $200m.
Flounder
Definition:
(n.) A flatfish of the family Pleuronectidae, of many species.
(n.) A tool used in crimping boot fronts.
(v. i.) To fling the limbs and body, as in making efforts to move; to struggle, as a horse in the mire, or as a fish on land; to roll, toss, and tumble; to flounce.
(n.) The act of floundering.
Example Sentences:
(1) Isolated renal tubules and renal clearance techniques were used to characterize the renal handling of 2-deoxy-D-galactose (2-d-Gal) by the winter flounder (Pseudopleuronectes americanus).
(2) The flounder developed renal and pancreatic neoplasms and hepatotoxic neoplastic precursor lesions, demonstrating trophic transfer of sediment-bound carcinogens up the food chain.
(3) The changes in arterial blood pressure and plasma cortisol concentration in response to exogenous angiotensin II (AII) and to manipulation of the endogenous renin-angiotensin system (RAS) have been examined in the flounder, Platichthys flesus.
(4) Both cortisol and thyroid hormones were detected in newly fertilized eggs of the Japanese flounder, Paralichthys olivaceus.
(5) And it has left the international community floundering as it tries to respond to conflicts spilling across the globe.
(6) With England floundering at 111 for five after 29 overs in pursuit of the 301 required for victory, he kept cracking the ball to the boundary in a manner way beyond his colleagues.
(7) DNA sequence analysis of a tandemly repeated gene from winter flounder showed that it can code for one of the two most abundant AFP components in the serum.
(8) According to a paper published in the journal Science on Thursday, large and bottom-dwelling species carry most risk, which means cod, flounder, halibut, pollock, skate and sole from the waters in question could be off limits for years, .
(9) The strategic locations are: Stratford, in east London, which is seen as an emerging Olympic city and centrepiece of the country's bid for the 2012 Olympics; Greenwich and Woolwich, involving new and rebuilt communities near the floundering millennium dome site; Barking, where work has already begun on a new township; Thurrock in Essex, involving a new urban development corporation with sweeping planning powers, and North Kent Thameside, between Dartford and Gravesend, which embraces Ebbsfleet.
(10) Metabolism of benzo(a)pyrene (BaP) in vivo and in vitro was studied using two benthic fish species, English sole (Parophrys vetulus) and starry flounder (Platichthys stellatus), and Sprague-Dawley rats.
(11) This was especially crucial in 2001, as Labor floundered in the face of a manufactured refugee crisis.
(12) We have investigated the volume-activated transport of organic solutes in flounder erythrocytes.
(13) The observation that two classes of neuronal depolarizing agents (veratrine and scorpion venom) cause TTX-sensitive inhibition of basal ion transport establishes that NaCl absorption in flounder intestine is subject to regulation by enteric nerves located in the submucosa.
(14) Zinc levels in windowpane flounder liver were about 6 to 9 times greater than the 4 to 10 ppm levels found in muscle.
(15) High rates of drinking in seawater-adapted, compared with freshwater (FW)-adapted, flounder were associated with raised plasma chloride and osmotic concentrations.
(16) The farmers, led by Peter Kendall, the NFU president, got cold feet last week, but were bounced into hanging in there by Paterson and Downing Street, the latter terrified of another U-turn in the week that saw David Cameron flounder on an energy bill pledge and his chief whip, Andrew Mitchell, resign.
(17) The level of chemical modification of hepatic DNA in juvenile flounder was 2-4 fold lower than that for juvenile sole and concentration of BaP 7,8-diol glucuronide in bile of sole was significantly higher than that in flounder bile, although the rate of formation of BaP 7,8-diol by hepatic microsomes was comparable for both species.
(18) Specifically, the yellowtail antifreeze protein, in contrast to that of the winter flounder, contains a fourth 11-amino-acid repeat and lacks several of the hydrophilic residues that have been postulated to aid in the binding of the protein to ice crystals.
(19) In the second experiment, premetamorphic flounder larvae were treated with two doses of T4 and three doses of T3.
(20) It is one thing that Mark Hughes, the only manager to guide the club to three successive top-half finishes in the top division and the introducer of a charming style of play, now seems to be floundering.