(v. t.) To lap or lay in plaits or folds; to lay one part over another part of; to double; as, to fold cloth; to fold a letter.
(v. t.) To double or lay together, as the arms or the hands; as, he folds his arms in despair.
(v. t.) To inclose within folds or plaitings; to envelop; to infold; to clasp; to embrace.
(v. t.) To cover or wrap up; to conceal.
(v. i.) To become folded, plaited, or doubled; to close over another of the same kind; to double together; as, the leaves of the door fold.
(v.) A doubling,esp. of any flexible substance; a part laid over on another part; a plait; a plication.
(v.) Times or repetitions; -- used with numerals, chiefly in composition, to denote multiplication or increase in a geometrical ratio, the doubling, tripling, etc., of anything; as, fourfold, four times, increased in a quadruple ratio, multiplied by four.
(v.) That which is folded together, or which infolds or envelops; embrace.
(n.) An inclosure for sheep; a sheep pen.
(n.) A flock of sheep; figuratively, the Church or a church; as, Christ's fold.
(n.) A boundary; a limit.
(v. t.) To confine in a fold, as sheep.
(v. i.) To confine sheep in a fold.
Example Sentences:
(1) Patient plasma samples demonstrated evidence of marked complement activation, with 3-fold elevations of C3a desArg concentrations by the 8th day of therapy.
(2) 5-Azacytidine (I) stability was increased approximately 10-fold over its stability in water or lactated Ringer injection by the addition of excess sodium bisulfite and the maintenance of pH approximately 2.5.
(3) Radioligand binding studies revealed the presence of a single class of high-affinity (Kd = 2-6 X 10(-10) M) binding sites for ET-1 in both cells, although the maximal binding capacity of cardiac receptor was about 6- to 12-fold greater than that of vascular receptor.
(4) The enzyme was solubilized by Triton X-100 and purified approximately 480-fold by gel filtration and affinity chromatography on alanine methyl ketone-AH-Sepharose 4B.
(5) The DNA untwisting enzyme has been purified approximately 300-fold from rat liver nuclei.
(6) IP3 increased 1.7-fold and IP2 1.6-fold after 20 and 40 s, respectively.
(7) Short incubations with heparin (5 min) caused a release of the enzyme into the media, while longer incubations caused a 2-8-fold increase in net lipoprotein lipase secretion which was maximal after 2-16 h depending on cell type, and persisted for 24 h. The effect of heparin was dose-dependent and specific (it was not duplicated by other glycosaminoglycans).
(8) The following conclusions emerge: (i) when the 3' or the 3' penultimate base of the oligonucleotide mismatched an allele, no amplification product could be detected; (ii) when the mismatches were 3 and 4 bases from the 3' end of the primer, differential amplification was still observed, but only at certain concentrations of magnesium chloride; (iii) the mismatched allele can be detected in the presence of a 40-fold excess of the matched allele; (iv) primers as short as 13 nucleotides were effective; and (v) the specificity of the amplification could be overwhelmed by greatly increasing the concentration of target DNA.
(9) Epicanthal folds were present in 46%, mongoloid slanting of the lids in 72% of cases.
(10) The estimated DNA compaction ratio (approximately 3-fold) is consistent with a significant degree of nucleosome unfolding in the hyperstimulated BR genes.
(11) Two hours after refeeding rats fasted for 48 h, ODC activity increased 40-fold in mucosa from the intact jejunum and 4-fold in the mucosa of the bypassed segments.
(12) Transfection of the treated DNA into SOS-induced spheroplasts results in an increase in mutagenesis as great as 50-fold.
(13) ACh released from the vesicular fraction was about 100-fold more than could be accounted for by miniature end-plate potentials; possible causes of this overestimate are discussed.
(14) In strains completely deleted for galR, the gene which encodes the Gal repressor, the operon is derepressed by only 10-fold without an inducer.
(15) The amount of water, creatinine, electrolytes, proteins, and enzymes were higher during the day (up to three fold, p always less than 0.05), while equal amounts of amino acids were excreted in the day and the night period.
(16) TNBS reacts to an extremely small extend with hemoglobin over the concentration range 0.4 to 4 mM whereas FDNB reacts with hemoglobin to a very large extent (50 fold more than TNBS).
(17) Rates of PC in vitro metabolism by liver and kidney cytosolic cysteine conjugate beta-lyases (beta-lyases) were similar, but metabolism by renal mitochondrial beta-lyase occurred at a 3-fold higher rate than the rate obtained with hepatic mitochondrial beta-lyase.
(18) Dietary factors affect intestinal P450s markedly--iron restriction rapidly decreased intestinal P450 to beneath detectable values; selenium deficiency acted similarly but was less effective; Brussels sprouts increased intestinal AHH activity 9.8-fold, ECOD activity 3.2-fold, and P450 1.9-fold; fried meat and dietary fat significantly increased intestinal EROD activity; a vitamin A-deficient diet increased, and a vitamin A-rich diet decreased intestinal P450 activities; and excess cholesterol in the diet increased intestinal P450 activity.
(19) On the other hand, if we correct for the population of HMM with degraded light chain 2, the difference in the binding constants in the presence and absence of Ca2+ may be as great as 5-fold.
(20) The gene, which is located at chromosome XIII, is transcribed as a mRNA of about 2.7 kilobases, and the amount of message has been found to increase 3- to 4-fold during the culture.
Infold
Definition:
(v. t.) To wrap up or cover with folds; to envelop; to inwrap; to inclose; to involve.
(v. t.) To clasp with the arms; to embrace.
Example Sentences:
(1) The wall of the yolk sac thickens as a result of this infolding and the densely packed capillaries.
(2) These alterations include fenestration, widened intercellular junctions, increase in pinocytotic vesicles, and infolding of the luminal surface.
(3) Later, the astroglial processes of regenerated glia limitans showed very infolded surfaces and numerous filaments inside of them.
(4) The surface of the zona was quite irregular and contained numerous infoldings, channels and crypts.
(5) Patches of displaced basal lamina material appeared within the RPE basal infoldings.
(6) The second tumour occurred in a 36-year-old woman, followed a benign course and showed papillary infoldings lined by multilayered neoplastic cells.
(7) Marked infolding of both the granulosa and theca tissue in some follicles suggested early luteinization.
(8) In the former cells, active mitochondria were generally found near microvilli at the apical ends and in the areas of the basal infoldings whereas those in a central position were more frequently unreactive.
(9) The cell outline shows remarkable complexity by extensive infoldings and interdigitations of lateral and basal plasma membranes.
(10) Expression of L1 was restricted to neural cells until approximately postnatal day 5, when L1 started to be detectable on crypt but not on villus cells, predominantly on the basolateral membrane infoldings.
(11) The processes in both eyes of the epinephrine-treated monkeys exhibited one of two pictures: dilated stromal capillaries with numerous fenestrations; normal stroma, PE basement membrane and PE; numerous well-developed NPE basolateral infoldings and enlarged mitochondria; dilated stromal capillaries with ruptured fenestrations; ballooned protein-filled stroma; degenerated NPE.
(12) Moreover, the basement membrane of the seminiferous tubule showed wavy lamellae and infolding to the seminiferous epithelium.
(13) Secretory ameloblasts synthesize the organic matrix of enamel and secrete it at two distinct "putative secretory sites" characterized by membrane infoldings (Nanci and Warshawsky, 1984a).
(14) The distance between the apposed rectus muscles is then progressively decreased by repeated infolding of the polyamide mesh with running longitudinal sutures on the mesh itself.
(15) In the anterior and middle part, the NPE cells have only a few membrane infoldings and few mitochondria in the cytoplasm, but abundant surfaces of rough endoplasmic reticulum, numerous ribosomes and Golgi material, indicating protein synthesis.
(16) Increase of vesicles in both the endothelial cells and the basal infoldings of pigment cells were features.
(17) Cell outlines were smooth, with no basal infoldings of the plasma membrane or apical microvilli.
(18) The ultrastructure of the Sertoli cell studied in sexually active control animals during May-June and experimental animals sexually activated by light in winter, presents the commonly described ramified aspect with an infolded nucleus, well developed Golgi complexes, rough and smooth endoplasmic reticulum, numerous microfilaments, few liposomes and lysosomal formations; In the regressed testes of hibernating animals or blinded spring animals, the Sertoli cells are more round shaped with a significant increase in number and size of liposomes, lysosomes and various necrotic bodies.
(19) Electron microscopy of surviving retinal pigment epithelial (RPE) cells indicated a loss of apical microvilli and basal infoldings.
(20) The latter, like the stacked membrane infoldings of rectal papillae, exhibit intercellular columns and numerous intramembranous P face particles; these are undoubtedly involved in ion transport.