(v. t.) To lap or lay in plaits or folds; to lay one part over another part of; to double; as, to fold cloth; to fold a letter.
(v. t.) To double or lay together, as the arms or the hands; as, he folds his arms in despair.
(v. t.) To inclose within folds or plaitings; to envelop; to infold; to clasp; to embrace.
(v. t.) To cover or wrap up; to conceal.
(v. i.) To become folded, plaited, or doubled; to close over another of the same kind; to double together; as, the leaves of the door fold.
(v.) A doubling,esp. of any flexible substance; a part laid over on another part; a plait; a plication.
(v.) Times or repetitions; -- used with numerals, chiefly in composition, to denote multiplication or increase in a geometrical ratio, the doubling, tripling, etc., of anything; as, fourfold, four times, increased in a quadruple ratio, multiplied by four.
(v.) That which is folded together, or which infolds or envelops; embrace.
(n.) An inclosure for sheep; a sheep pen.
(n.) A flock of sheep; figuratively, the Church or a church; as, Christ's fold.
(n.) A boundary; a limit.
(v. t.) To confine in a fold, as sheep.
(v. i.) To confine sheep in a fold.
Example Sentences:
(1) Patient plasma samples demonstrated evidence of marked complement activation, with 3-fold elevations of C3a desArg concentrations by the 8th day of therapy.
(2) 5-Azacytidine (I) stability was increased approximately 10-fold over its stability in water or lactated Ringer injection by the addition of excess sodium bisulfite and the maintenance of pH approximately 2.5.
(3) Radioligand binding studies revealed the presence of a single class of high-affinity (Kd = 2-6 X 10(-10) M) binding sites for ET-1 in both cells, although the maximal binding capacity of cardiac receptor was about 6- to 12-fold greater than that of vascular receptor.
(4) The enzyme was solubilized by Triton X-100 and purified approximately 480-fold by gel filtration and affinity chromatography on alanine methyl ketone-AH-Sepharose 4B.
(5) The DNA untwisting enzyme has been purified approximately 300-fold from rat liver nuclei.
(6) IP3 increased 1.7-fold and IP2 1.6-fold after 20 and 40 s, respectively.
(7) Short incubations with heparin (5 min) caused a release of the enzyme into the media, while longer incubations caused a 2-8-fold increase in net lipoprotein lipase secretion which was maximal after 2-16 h depending on cell type, and persisted for 24 h. The effect of heparin was dose-dependent and specific (it was not duplicated by other glycosaminoglycans).
(8) The following conclusions emerge: (i) when the 3' or the 3' penultimate base of the oligonucleotide mismatched an allele, no amplification product could be detected; (ii) when the mismatches were 3 and 4 bases from the 3' end of the primer, differential amplification was still observed, but only at certain concentrations of magnesium chloride; (iii) the mismatched allele can be detected in the presence of a 40-fold excess of the matched allele; (iv) primers as short as 13 nucleotides were effective; and (v) the specificity of the amplification could be overwhelmed by greatly increasing the concentration of target DNA.
(9) Epicanthal folds were present in 46%, mongoloid slanting of the lids in 72% of cases.
(10) The estimated DNA compaction ratio (approximately 3-fold) is consistent with a significant degree of nucleosome unfolding in the hyperstimulated BR genes.
(11) Two hours after refeeding rats fasted for 48 h, ODC activity increased 40-fold in mucosa from the intact jejunum and 4-fold in the mucosa of the bypassed segments.
(12) Transfection of the treated DNA into SOS-induced spheroplasts results in an increase in mutagenesis as great as 50-fold.
(13) ACh released from the vesicular fraction was about 100-fold more than could be accounted for by miniature end-plate potentials; possible causes of this overestimate are discussed.
(14) In strains completely deleted for galR, the gene which encodes the Gal repressor, the operon is derepressed by only 10-fold without an inducer.
(15) The amount of water, creatinine, electrolytes, proteins, and enzymes were higher during the day (up to three fold, p always less than 0.05), while equal amounts of amino acids were excreted in the day and the night period.
(16) TNBS reacts to an extremely small extend with hemoglobin over the concentration range 0.4 to 4 mM whereas FDNB reacts with hemoglobin to a very large extent (50 fold more than TNBS).
(17) Rates of PC in vitro metabolism by liver and kidney cytosolic cysteine conjugate beta-lyases (beta-lyases) were similar, but metabolism by renal mitochondrial beta-lyase occurred at a 3-fold higher rate than the rate obtained with hepatic mitochondrial beta-lyase.
(18) Dietary factors affect intestinal P450s markedly--iron restriction rapidly decreased intestinal P450 to beneath detectable values; selenium deficiency acted similarly but was less effective; Brussels sprouts increased intestinal AHH activity 9.8-fold, ECOD activity 3.2-fold, and P450 1.9-fold; fried meat and dietary fat significantly increased intestinal EROD activity; a vitamin A-deficient diet increased, and a vitamin A-rich diet decreased intestinal P450 activities; and excess cholesterol in the diet increased intestinal P450 activity.
(19) On the other hand, if we correct for the population of HMM with degraded light chain 2, the difference in the binding constants in the presence and absence of Ca2+ may be as great as 5-fold.
(20) The gene, which is located at chromosome XIII, is transcribed as a mRNA of about 2.7 kilobases, and the amount of message has been found to increase 3- to 4-fold during the culture.
Lap
Definition:
(n.) The loose part of a coat; the lower part of a garment that plays loosely; a skirt; an apron.
(n.) An edge; a border; a hem, as of cloth.
(n.) The part of the clothing that lies on the knees or thighs when one sits down; that part of the person thus covered; figuratively, a place of rearing and fostering; as, to be reared in the lap of luxury.
(n.) That part of any substance or fixture which extends over, or lies upon, or by the side of, a part of another; as, the lap of a board; also, the measure of such extension over or upon another thing.
(n.) The amount by which a slide valve at its half stroke overlaps a port in the seat, being equal to the distance the valve must move from its mid stroke position in order to begin to open the port. Used alone, lap refers to outside lap. See Outside lap (below).
(n.) The state or condition of being in part extended over or by the side of something else; or the extent of the overlapping; as, the second boat got a lap of half its length on the leader.
(n.) One circuit around a race track, esp. when the distance is a small fraction of a mile; as, to run twenty laps; to win by three laps. See Lap, to fold, 2.
(n.) In card playing and other games, the points won in excess of the number necessary to complete a game; -- so called when they are counted in the score of the following game.
(n.) A sheet, layer, or bat, of cotton fiber prepared for the carding machine.
(n.) A piece of brass, lead, or other soft metal, used to hold a cutting or polishing powder in cutting glass, gems, and the like, or in polishing cutlery, etc. It is usually in the form of wheel or disk, which revolves on a vertical axis.
(v. t.) To rest or recline in a lap, or as in a lap.
(v. t.) To cut or polish with a lap, as glass, gems, cutlery, etc. See 1st Lap, 10.
(n.) To fold; to bend and lay over or on something; as, to lap a piece of cloth.
(n.) To wrap or wind around something.
(n.) To infold; to hold as in one's lap; to cherish.
(n.) To lay or place over anything so as to partly or wholly cover it; as, to lap one shingle over another; to lay together one partly over another; as, to lap weather-boards; also, to be partly over, or by the side of (something); as, the hinder boat lapped the foremost one.
(n.) To lay together one over another, as fleeces or slivers for further working.
(v. i.) To be turned or folded; to lie partly upon or by the side of something, or of one another; as, the cloth laps back; the boats lap; the edges lap.
(v. i.) To take up drink or food with the tongue; to drink or feed by licking up something.
(v. i.) To make a sound like that produced by taking up drink with the tongue.
(v. t.) To take into the mouth with the tongue; to lick up with a quick motion of the tongue.
(n.) The act of lapping with, or as with, the tongue; as, to take anything into the mouth with a lap.
(n.) The sound of lapping.
Example Sentences:
(1) On the other hand, the LAP level, identical in preterms and SDB, is lower than in full-term infants but higher than in adults.
(2) We conclude that plasma LAP measurements have little value in monitoring ovulation induction therapy.
(3) A light rain pattered the rooftops of Los Mochis in Friday’s pre-dawn darkness, the town silent and still as the Sea of Cortez lapped its shore.
(4) Experimentally induced tongue contact with a variety of solid surfaces during lapping (an activity involving accumulation of a liquid bolus in the valleculae) induced neither increased jaw opening nor the additional EMG pattern.
(5) Kester said her daughter came and cried in her lap.
(6) 1.08pm BST Lap 2: Sergio Perez is out after an incident at Mirabeau, which is what brought out the yellow flags and safety car.
(7) By comparing P-LAP activity with cystine aminopeptidase activity, we concluded that both activities were shared by the same molecule.
(8) 1.57pm BST Lap 36: Punchy stuff from Jules Bianchi up to 13th, literally bumping his way through Kobayashi on the inside.
(9) The new tablet models come with a better built-in kickstand with two positions rather than one, so they can rest more firmly on users' laps.
(10) After Manchester United came the long goodbye to Stamford Bridge, a home game against Leeds on 15 May 2004, Abramovich's dismissal notice in Ranieri's pocket, but a lap and guard of honour with the players.
(11) Having personally witnessed their live act (Black Flag frantically twanging Bootsy’s Rubber Band) at Dingwalls in late August, I thought I’d made a great discovery until, two breathless days later, and a mere few hours before they left these fair isles, the Peppers deposited their press kit in my lap.
(12) Analysis of the activity of each unit was made at intervals from the beginning of the conditioned signal (light or sound) to the beginning of lapping milk which appeared in the feeding trough after the cat pressed the pedal.
(13) (2) The alleles at the Est-1, Est-2, Amy loci and the AP-4(1.0) and the LAP-1(.90) alleles show north south clinal change in frequency.
(14) On the other hand, grinding the glossy ridge-lap surface, painting the teeth with monomer or a solvent, preparing retention grooves on the ridge-lap portion of the teeth effectively lock the teeth to the denture base.
(15) We correlated Doppler variables of pulmonary venous flow and mitral inflow with simultaneously obtained mean LAP and changes in pressure measured by left atrial or pulmonary artery catheters.
(16) However, saccharin does not trigger a fixed rate of lapping at any point in the sequence.
(17) We might as well put a white cat in his lap.” The photographer asks McCluskey to hold the king up to the camera, and the press officer laughs with a wince.
(18) The race itself will feature 120 cyclists starting at 12.45pm and covering 13 laps of the Tour's finish circuit up and down the Champs Elysées, turning at Place de la Concorde and at the Arc de Triomphe, with a total distance of 90 kilometres.
(19) A significant LAP activity decrease was found only after a 30 day postcastration period when naloxone treated intact animals were compared with the castrated rats.
(20) These results suggest that P-LAP shows oxytocinase activity and plays an important role in the regulation of the plasma level of these hormones during pregnancy.