(v. t.) To lap or lay in plaits or folds; to lay one part over another part of; to double; as, to fold cloth; to fold a letter.
(v. t.) To double or lay together, as the arms or the hands; as, he folds his arms in despair.
(v. t.) To inclose within folds or plaitings; to envelop; to infold; to clasp; to embrace.
(v. t.) To cover or wrap up; to conceal.
(v. i.) To become folded, plaited, or doubled; to close over another of the same kind; to double together; as, the leaves of the door fold.
(v.) A doubling,esp. of any flexible substance; a part laid over on another part; a plait; a plication.
(v.) Times or repetitions; -- used with numerals, chiefly in composition, to denote multiplication or increase in a geometrical ratio, the doubling, tripling, etc., of anything; as, fourfold, four times, increased in a quadruple ratio, multiplied by four.
(v.) That which is folded together, or which infolds or envelops; embrace.
(n.) An inclosure for sheep; a sheep pen.
(n.) A flock of sheep; figuratively, the Church or a church; as, Christ's fold.
(n.) A boundary; a limit.
(v. t.) To confine in a fold, as sheep.
(v. i.) To confine sheep in a fold.
Example Sentences:
(1) Patient plasma samples demonstrated evidence of marked complement activation, with 3-fold elevations of C3a desArg concentrations by the 8th day of therapy.
(2) 5-Azacytidine (I) stability was increased approximately 10-fold over its stability in water or lactated Ringer injection by the addition of excess sodium bisulfite and the maintenance of pH approximately 2.5.
(3) Radioligand binding studies revealed the presence of a single class of high-affinity (Kd = 2-6 X 10(-10) M) binding sites for ET-1 in both cells, although the maximal binding capacity of cardiac receptor was about 6- to 12-fold greater than that of vascular receptor.
(4) The enzyme was solubilized by Triton X-100 and purified approximately 480-fold by gel filtration and affinity chromatography on alanine methyl ketone-AH-Sepharose 4B.
(5) The DNA untwisting enzyme has been purified approximately 300-fold from rat liver nuclei.
(6) IP3 increased 1.7-fold and IP2 1.6-fold after 20 and 40 s, respectively.
(7) Short incubations with heparin (5 min) caused a release of the enzyme into the media, while longer incubations caused a 2-8-fold increase in net lipoprotein lipase secretion which was maximal after 2-16 h depending on cell type, and persisted for 24 h. The effect of heparin was dose-dependent and specific (it was not duplicated by other glycosaminoglycans).
(8) The following conclusions emerge: (i) when the 3' or the 3' penultimate base of the oligonucleotide mismatched an allele, no amplification product could be detected; (ii) when the mismatches were 3 and 4 bases from the 3' end of the primer, differential amplification was still observed, but only at certain concentrations of magnesium chloride; (iii) the mismatched allele can be detected in the presence of a 40-fold excess of the matched allele; (iv) primers as short as 13 nucleotides were effective; and (v) the specificity of the amplification could be overwhelmed by greatly increasing the concentration of target DNA.
(9) Epicanthal folds were present in 46%, mongoloid slanting of the lids in 72% of cases.
(10) The estimated DNA compaction ratio (approximately 3-fold) is consistent with a significant degree of nucleosome unfolding in the hyperstimulated BR genes.
(11) Two hours after refeeding rats fasted for 48 h, ODC activity increased 40-fold in mucosa from the intact jejunum and 4-fold in the mucosa of the bypassed segments.
(12) Transfection of the treated DNA into SOS-induced spheroplasts results in an increase in mutagenesis as great as 50-fold.
(13) ACh released from the vesicular fraction was about 100-fold more than could be accounted for by miniature end-plate potentials; possible causes of this overestimate are discussed.
(14) In strains completely deleted for galR, the gene which encodes the Gal repressor, the operon is derepressed by only 10-fold without an inducer.
(15) The amount of water, creatinine, electrolytes, proteins, and enzymes were higher during the day (up to three fold, p always less than 0.05), while equal amounts of amino acids were excreted in the day and the night period.
(16) TNBS reacts to an extremely small extend with hemoglobin over the concentration range 0.4 to 4 mM whereas FDNB reacts with hemoglobin to a very large extent (50 fold more than TNBS).
(17) Rates of PC in vitro metabolism by liver and kidney cytosolic cysteine conjugate beta-lyases (beta-lyases) were similar, but metabolism by renal mitochondrial beta-lyase occurred at a 3-fold higher rate than the rate obtained with hepatic mitochondrial beta-lyase.
(18) Dietary factors affect intestinal P450s markedly--iron restriction rapidly decreased intestinal P450 to beneath detectable values; selenium deficiency acted similarly but was less effective; Brussels sprouts increased intestinal AHH activity 9.8-fold, ECOD activity 3.2-fold, and P450 1.9-fold; fried meat and dietary fat significantly increased intestinal EROD activity; a vitamin A-deficient diet increased, and a vitamin A-rich diet decreased intestinal P450 activities; and excess cholesterol in the diet increased intestinal P450 activity.
(19) On the other hand, if we correct for the population of HMM with degraded light chain 2, the difference in the binding constants in the presence and absence of Ca2+ may be as great as 5-fold.
(20) The gene, which is located at chromosome XIII, is transcribed as a mRNA of about 2.7 kilobases, and the amount of message has been found to increase 3- to 4-fold during the culture.
Penfold
Definition:
(n.) See Pinfold.
Example Sentences:
(1) Barry O'Farrell resigned the day after telling the Independent Commission Against Corruption he did not remember receiving a gift of a $3000 bottle of Penfolds Grange from Australian Water Holdings chief Nick di Girolamo in 2011.
(2) The NSW premier said: “I don’t know about this phone call, but what I do know is if I’d received a bottle of 1959 Penfold Grange I’d have known about it.” O’Farrell said he first met Di Girolamo in 2007 after becoming state Liberal leader and maintained “once a month” contact with the prominent Liberal party fundraiser in the lead-up to the 2011 election.
(3) 1.57am BST Barry O'Farrell has just resigned over his evidence to Icac, in which he said he did not receive a gift of a 1959 bottle of Penfolds Grange Hermitage from the head of Australian Water Holdings, Nick Di Girolamo.
(4) The move raises the prospect of a bidding war for Treasury, which owns the Penfolds, Wolf Blass and Beringer brands.
(5) 3.51am BST Remember yesterday the commission was presented evidence by Direct Couriers, the company who delivered the wine, that the 1959 bottle of Penfolds Grange had been delivered to O'Farrell's unattended Roseville home on 20 April, and was left on the porch.
(6) He has not specifically said if he plans to stay in parliament after resigning as premier on Wednesday when a handwritten note emerged in which he thanked the former Australian Water Holdings (AWH) chief executive Nick Di Girolamo for a $3,000 bottle of 1959 Penfolds Grange in 2011.
(7) O’Farrell resigned after insisting under oath that he never received a 1959 bottle of Penfolds Grange from a Liberal fundraiser, only to have a thank-you note for the wine in his handwriting surface the following day.
(8) Twitter wit begins: Earl Penfold ('66) (@PSyvret) There's your headline: RT " @mattjpwns WALKING THE PLONK" April 16, 2014 2.16am BST More from Lenore Taylor: “In public life you meet people, and from time to time they give you things, they might give you ties, they might give you pens...sure a bottle of grange is pretty special.” Asked when he had learned of O’Farrell’s bombshell decision, Abbott said “he texted me that I should call him, by the time I saw the text he was about to go in and make his statement.
(9) The event is sponsored by the makers of the vintage Australian wine, Penfolds Grange.
(10) O’Farrell denied receiving the bottle of 1959 Penfolds Grange when he gave evidence to Icac on Tuesday.
(11) But the company is turning round its fortunes with an ongoing restructuring plan, bolstered by Asia's growing appetite for wine and the value of the Penfolds label.
(12) Greg Dyke will be speaking about his career at the Penfolds' Vintage Years event on 2 November at The Hospital Club, London, at 7pm.
(13) The New South Wales premier, Barry O’Farrell, has denied receiving a 1959 bottle of Penfolds Grange wine valued at $3,000 from the former chief executive of Australian Water Holdings, Nick Di Girolamo.
(14) The records it produced showed that the 1959 bottle of Penfolds Grange had been delivered to O'Farrell's unattended Roseville home on 20 April, where it was left on the porch.