(v. t.) To lap or lay in plaits or folds; to lay one part over another part of; to double; as, to fold cloth; to fold a letter.
(v. t.) To double or lay together, as the arms or the hands; as, he folds his arms in despair.
(v. t.) To inclose within folds or plaitings; to envelop; to infold; to clasp; to embrace.
(v. t.) To cover or wrap up; to conceal.
(v. i.) To become folded, plaited, or doubled; to close over another of the same kind; to double together; as, the leaves of the door fold.
(v.) A doubling,esp. of any flexible substance; a part laid over on another part; a plait; a plication.
(v.) Times or repetitions; -- used with numerals, chiefly in composition, to denote multiplication or increase in a geometrical ratio, the doubling, tripling, etc., of anything; as, fourfold, four times, increased in a quadruple ratio, multiplied by four.
(v.) That which is folded together, or which infolds or envelops; embrace.
(n.) An inclosure for sheep; a sheep pen.
(n.) A flock of sheep; figuratively, the Church or a church; as, Christ's fold.
(n.) A boundary; a limit.
(v. t.) To confine in a fold, as sheep.
(v. i.) To confine sheep in a fold.
Example Sentences:
(1) Patient plasma samples demonstrated evidence of marked complement activation, with 3-fold elevations of C3a desArg concentrations by the 8th day of therapy.
(2) 5-Azacytidine (I) stability was increased approximately 10-fold over its stability in water or lactated Ringer injection by the addition of excess sodium bisulfite and the maintenance of pH approximately 2.5.
(3) Radioligand binding studies revealed the presence of a single class of high-affinity (Kd = 2-6 X 10(-10) M) binding sites for ET-1 in both cells, although the maximal binding capacity of cardiac receptor was about 6- to 12-fold greater than that of vascular receptor.
(4) The enzyme was solubilized by Triton X-100 and purified approximately 480-fold by gel filtration and affinity chromatography on alanine methyl ketone-AH-Sepharose 4B.
(5) The DNA untwisting enzyme has been purified approximately 300-fold from rat liver nuclei.
(6) IP3 increased 1.7-fold and IP2 1.6-fold after 20 and 40 s, respectively.
(7) Short incubations with heparin (5 min) caused a release of the enzyme into the media, while longer incubations caused a 2-8-fold increase in net lipoprotein lipase secretion which was maximal after 2-16 h depending on cell type, and persisted for 24 h. The effect of heparin was dose-dependent and specific (it was not duplicated by other glycosaminoglycans).
(8) The following conclusions emerge: (i) when the 3' or the 3' penultimate base of the oligonucleotide mismatched an allele, no amplification product could be detected; (ii) when the mismatches were 3 and 4 bases from the 3' end of the primer, differential amplification was still observed, but only at certain concentrations of magnesium chloride; (iii) the mismatched allele can be detected in the presence of a 40-fold excess of the matched allele; (iv) primers as short as 13 nucleotides were effective; and (v) the specificity of the amplification could be overwhelmed by greatly increasing the concentration of target DNA.
(9) Epicanthal folds were present in 46%, mongoloid slanting of the lids in 72% of cases.
(10) The estimated DNA compaction ratio (approximately 3-fold) is consistent with a significant degree of nucleosome unfolding in the hyperstimulated BR genes.
(11) Two hours after refeeding rats fasted for 48 h, ODC activity increased 40-fold in mucosa from the intact jejunum and 4-fold in the mucosa of the bypassed segments.
(12) Transfection of the treated DNA into SOS-induced spheroplasts results in an increase in mutagenesis as great as 50-fold.
(13) ACh released from the vesicular fraction was about 100-fold more than could be accounted for by miniature end-plate potentials; possible causes of this overestimate are discussed.
(14) In strains completely deleted for galR, the gene which encodes the Gal repressor, the operon is derepressed by only 10-fold without an inducer.
(15) The amount of water, creatinine, electrolytes, proteins, and enzymes were higher during the day (up to three fold, p always less than 0.05), while equal amounts of amino acids were excreted in the day and the night period.
(16) TNBS reacts to an extremely small extend with hemoglobin over the concentration range 0.4 to 4 mM whereas FDNB reacts with hemoglobin to a very large extent (50 fold more than TNBS).
(17) Rates of PC in vitro metabolism by liver and kidney cytosolic cysteine conjugate beta-lyases (beta-lyases) were similar, but metabolism by renal mitochondrial beta-lyase occurred at a 3-fold higher rate than the rate obtained with hepatic mitochondrial beta-lyase.
(18) Dietary factors affect intestinal P450s markedly--iron restriction rapidly decreased intestinal P450 to beneath detectable values; selenium deficiency acted similarly but was less effective; Brussels sprouts increased intestinal AHH activity 9.8-fold, ECOD activity 3.2-fold, and P450 1.9-fold; fried meat and dietary fat significantly increased intestinal EROD activity; a vitamin A-deficient diet increased, and a vitamin A-rich diet decreased intestinal P450 activities; and excess cholesterol in the diet increased intestinal P450 activity.
(19) On the other hand, if we correct for the population of HMM with degraded light chain 2, the difference in the binding constants in the presence and absence of Ca2+ may be as great as 5-fold.
(20) The gene, which is located at chromosome XIII, is transcribed as a mRNA of about 2.7 kilobases, and the amount of message has been found to increase 3- to 4-fold during the culture.
Plight
Definition:
() imp. & p. p. of Plight, to pledge.
() imp. & p. p. of Pluck.
(v. t.) To weave; to braid; to fold; to plait.
(n.) A network; a plait; a fold; rarely a garment.
(n.) That which is exposed to risk; that which is plighted or pledged; security; a gage; a pledge.
(n.) Condition; state; -- risk, or exposure to danger, often being implied; as, a luckless plight.
(n.) To pledge; to give as a pledge for the performance of some act; as, to plight faith, honor, word; -- never applied to property or goods.
(n.) To promise; to engage; to betroth.
Example Sentences:
(1) Now, a small Scottish charity, Edinburgh Direct Aid – moved by their plight and aware that the language of Lebanese education is French and English and that Syria is Arabic – is delivering textbooks in Arabic to the school and have offered to fund timeshare projects across the country.
(2) A 76-year-old British national has been held in an Iranian jail for more than four years and convicted of spying, his family has revealed, as they seek to draw attention to the plight of a man they describe as one of the “oldest and loneliest prisoners in Iran”.
(3) A prominent gay rights activist, Nikolai Alexeev, said although Fry's letter "won't change anything" at the Olympics, it would help raise awareness of the plight of LGBT Russians.
(4) Greece's desperate plight hovers over the meeting, although formally there is no mention of Greece on the agenda or in the statements drafted for the meeting.
(5) Persistent media highlighting of the plight of patients suffering from severe fatigue of unknown cause (postviral fatigue syndrome or myalgic encephalomyelitis) has at last been matched by professional attention.
(6) "But if it keeps their plight and the plight of the Arctic in the press, I think she would be happy to do it."
(7) What he didn’t foresee was that getting to know people more intimately would result in his using portraits – more than 130 so far – to raise awareness of the plight of chronic homelessness generally or that he would become passionately vocal about what has been an entrenched issue for a number of US cities for decades.
(8) Sting – a man who had split the Police to pursue a more adult-oriented career, and who would in the following year ponder such poptastic issues as how much Russians loved their children and the plight of miners – took that job in 1984, while this year it falls to Guy Garvey, who may as well just change his middle name to 6Music.
(9) Victims of the Great Depression were there in plain sight, the unemployed queuing up in breadlines, their plight unambiguous.
(10) Qatar had vowed to reform the industry after the Guardian exposed the desperate plight of many of its migrant workers last year.
(11) I keep going and going and going.” 17) Being ahead of the curve July 2008: Two years before the Qatar vote, addresses the plight of exploited workers denied liveable pay and conditions.
(12) The legitimate focus on the plight of refugees on Nauru has overshadowed the impact of Australian policies on that island nation, a closely integrated society of just 10,000 people.
(13) Last week the International Consortium of British Pensioners (ICBP), which represents expat campaigning groups in Australia and Canada, launched its new Pension Justice website , aimed at highlighting their plight.
(14) Few measures have elicited more anger – or ingenious forms of revolt – than the property tax announced by Greek ministers to plug a budget black hole that might have gone unnoticed had Greece's plight not threatened the entire eurozone.
(15) With 73,000 people killed and large parts of its cities and villages destroyed in the north by the disaster, the plight of 2.5 million people left homeless hung in the balance.
(16) They seem to be unaware of the plight of this particular group of British savers.
(17) We have long been campaigning on the issue of income drawdown restrictions and so are pleased to see the government taking heed of the plight of these savers.
(18) But the strike proved a seminal moment in the British labour movement, drawing attention to the overlooked plight of female migrant workers – and generating admiration for Desai's tenacity.
(19) As for Aloisi's plight, Popovic declined to offer advice.
(20) Restrictions on local news agencies and newspapers seem to have eased recently with a few going as far as breaking the taboo on reporting the plight of political prisoners or the house arrests of opposition leaders.