What's the difference between fold and syncline?

Fold


Definition:

  • (v. t.) To lap or lay in plaits or folds; to lay one part over another part of; to double; as, to fold cloth; to fold a letter.
  • (v. t.) To double or lay together, as the arms or the hands; as, he folds his arms in despair.
  • (v. t.) To inclose within folds or plaitings; to envelop; to infold; to clasp; to embrace.
  • (v. t.) To cover or wrap up; to conceal.
  • (v. i.) To become folded, plaited, or doubled; to close over another of the same kind; to double together; as, the leaves of the door fold.
  • (v.) A doubling,esp. of any flexible substance; a part laid over on another part; a plait; a plication.
  • (v.) Times or repetitions; -- used with numerals, chiefly in composition, to denote multiplication or increase in a geometrical ratio, the doubling, tripling, etc., of anything; as, fourfold, four times, increased in a quadruple ratio, multiplied by four.
  • (v.) That which is folded together, or which infolds or envelops; embrace.
  • (n.) An inclosure for sheep; a sheep pen.
  • (n.) A flock of sheep; figuratively, the Church or a church; as, Christ's fold.
  • (n.) A boundary; a limit.
  • (v. t.) To confine in a fold, as sheep.
  • (v. i.) To confine sheep in a fold.

Example Sentences:

  • (1) Patient plasma samples demonstrated evidence of marked complement activation, with 3-fold elevations of C3a desArg concentrations by the 8th day of therapy.
  • (2) 5-Azacytidine (I) stability was increased approximately 10-fold over its stability in water or lactated Ringer injection by the addition of excess sodium bisulfite and the maintenance of pH approximately 2.5.
  • (3) Radioligand binding studies revealed the presence of a single class of high-affinity (Kd = 2-6 X 10(-10) M) binding sites for ET-1 in both cells, although the maximal binding capacity of cardiac receptor was about 6- to 12-fold greater than that of vascular receptor.
  • (4) The enzyme was solubilized by Triton X-100 and purified approximately 480-fold by gel filtration and affinity chromatography on alanine methyl ketone-AH-Sepharose 4B.
  • (5) The DNA untwisting enzyme has been purified approximately 300-fold from rat liver nuclei.
  • (6) IP3 increased 1.7-fold and IP2 1.6-fold after 20 and 40 s, respectively.
  • (7) Short incubations with heparin (5 min) caused a release of the enzyme into the media, while longer incubations caused a 2-8-fold increase in net lipoprotein lipase secretion which was maximal after 2-16 h depending on cell type, and persisted for 24 h. The effect of heparin was dose-dependent and specific (it was not duplicated by other glycosaminoglycans).
  • (8) The following conclusions emerge: (i) when the 3' or the 3' penultimate base of the oligonucleotide mismatched an allele, no amplification product could be detected; (ii) when the mismatches were 3 and 4 bases from the 3' end of the primer, differential amplification was still observed, but only at certain concentrations of magnesium chloride; (iii) the mismatched allele can be detected in the presence of a 40-fold excess of the matched allele; (iv) primers as short as 13 nucleotides were effective; and (v) the specificity of the amplification could be overwhelmed by greatly increasing the concentration of target DNA.
  • (9) Epicanthal folds were present in 46%, mongoloid slanting of the lids in 72% of cases.
  • (10) The estimated DNA compaction ratio (approximately 3-fold) is consistent with a significant degree of nucleosome unfolding in the hyperstimulated BR genes.
  • (11) Two hours after refeeding rats fasted for 48 h, ODC activity increased 40-fold in mucosa from the intact jejunum and 4-fold in the mucosa of the bypassed segments.
  • (12) Transfection of the treated DNA into SOS-induced spheroplasts results in an increase in mutagenesis as great as 50-fold.
  • (13) ACh released from the vesicular fraction was about 100-fold more than could be accounted for by miniature end-plate potentials; possible causes of this overestimate are discussed.
  • (14) In strains completely deleted for galR, the gene which encodes the Gal repressor, the operon is derepressed by only 10-fold without an inducer.
  • (15) The amount of water, creatinine, electrolytes, proteins, and enzymes were higher during the day (up to three fold, p always less than 0.05), while equal amounts of amino acids were excreted in the day and the night period.
  • (16) TNBS reacts to an extremely small extend with hemoglobin over the concentration range 0.4 to 4 mM whereas FDNB reacts with hemoglobin to a very large extent (50 fold more than TNBS).
  • (17) Rates of PC in vitro metabolism by liver and kidney cytosolic cysteine conjugate beta-lyases (beta-lyases) were similar, but metabolism by renal mitochondrial beta-lyase occurred at a 3-fold higher rate than the rate obtained with hepatic mitochondrial beta-lyase.
  • (18) Dietary factors affect intestinal P450s markedly--iron restriction rapidly decreased intestinal P450 to beneath detectable values; selenium deficiency acted similarly but was less effective; Brussels sprouts increased intestinal AHH activity 9.8-fold, ECOD activity 3.2-fold, and P450 1.9-fold; fried meat and dietary fat significantly increased intestinal EROD activity; a vitamin A-deficient diet increased, and a vitamin A-rich diet decreased intestinal P450 activities; and excess cholesterol in the diet increased intestinal P450 activity.
  • (19) On the other hand, if we correct for the population of HMM with degraded light chain 2, the difference in the binding constants in the presence and absence of Ca2+ may be as great as 5-fold.
  • (20) The gene, which is located at chromosome XIII, is transcribed as a mRNA of about 2.7 kilobases, and the amount of message has been found to increase 3- to 4-fold during the culture.

Syncline


Definition:

  • (n.) A synclinal fold.

Example Sentences:

  • (1) The two structures are mirror images and the central C--C--N--C--C chain adopts the anti-periplanar-synclinal conformation.
  • (2) In both monomeric and aggregated states the phosphocholine function of 1 adopts the synclinal conformation (alpha 5 torsional angle), in analogy with phosphatidylcholine (Hauser, H., Guyer, W., Pascher, I., Skrabal, P. and Sundell, S. (1980) Biochemistry 19, 366-373).
  • (3) The requirements of compounds in the cyclamate series for sweet taste stimulation are: synclinal conformation between NH and SO in the aminosulphonate group, length less than 0.7 nm of the group on the nitrogen, and hydrophobic character of the latter group.
  • (4) The alpha-methyl group is fully extended (antiplanar) whereas the amino group is orientated back towards the ring (synclinal).
  • (5) The compound is a potential antiarrhythmic and the molecule has the typical synclinal conformation for the -NH-CH-CH2-OH fragment of the side chain [tau CC = 56.5 (8) degrees] exhibited by these compounds.
  • (6) A comparison with the native crystal structure, where SO-4(2) is bound, revealed five changes: (a) a 0.10-nm shift of the anion-binding site; (b) a further closing of the flexible loop of the enzyme; (c) a 'swinging in' of the side chain of the catalytic Glu, that is chi 1 changes from (+) to (-) synclinal; (d) an altered water structure; (e) a disappearance of the conformational heterogeneity at the C-terminus of strand beta 7.
  • (7) One of these (rotamer A) is characterized by torsion angles theta 3 = antiperiplanar, theta 4 = +synclinal, and the other (rotamer B) by theta 3 = +synclinal, theta 4 = -synclinal.
  • (8) In both rotamers A and B the ester oxygens on the glycerol carbon atoms C(2) and C(3) are synclinal, and hence both types of rotamers readily allow the parallel alignment of the two hydrocarbon chains.
  • (9) The two fatty acid substituted glycerol oxygens have mutually a - synclinal rather than the more common + synclinal conformation.
  • (10) The X-ray crystal structure conformation for compound 22 (2-[2-(1H-indol-3-yl)ethyl]-3-]-3-(1-methylethoxy) phenyl]-4(3H)-quinazolinone, IC50 = 0.026 microM) is extended with the two heteroaromatic rings adopting an antiperiplanar arrangement around the central sigma bond of the ethane linker, whereas the solid-state conformation for a less active analogue 19 (2-[2-(1H-indol-3-yl)-1-methylethyl]-3-[3-(1- methylethoxy)phenyl]-4(3H)-quinazolinone, IC50 = 9.1 microM) is folded with the two heteroaromatic systems adopting a synclinal orientation.
  • (11) Whereas both solid-state (+-)-orphenadrine hydrochloride and diphenhydramine hydrochloride [(CH3)2NCH2CH2OCH(Ph)2.HCl] have synclinal N-C-C-O and antiperiplanar NC-C-O-CAr2 torsion angles, the former has a helical arrangement for Ar2CH, as expected, and the phenyl rings in the latter are disposed in a nonhelical, "open-book" arrangement.
  • (12) The conformation about the C1-C2 bond (theta 1 angle) of the sphingosine backbone is predominantly -synclinal, analogously to the conformation of the crystalline galactosyl cerebroside (Pascher, I. and Sundell, S. (1977) Chem.

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