(1) Patient plasma samples demonstrated evidence of marked complement activation, with 3-fold elevations of C3a desArg concentrations by the 8th day of therapy.
(2) 5-Azacytidine (I) stability was increased approximately 10-fold over its stability in water or lactated Ringer injection by the addition of excess sodium bisulfite and the maintenance of pH approximately 2.5.
(3) Radioligand binding studies revealed the presence of a single class of high-affinity (Kd = 2-6 X 10(-10) M) binding sites for ET-1 in both cells, although the maximal binding capacity of cardiac receptor was about 6- to 12-fold greater than that of vascular receptor.
(4) The enzyme was solubilized by Triton X-100 and purified approximately 480-fold by gel filtration and affinity chromatography on alanine methyl ketone-AH-Sepharose 4B.
(5) The DNA untwisting enzyme has been purified approximately 300-fold from rat liver nuclei.
(6) IP3 increased 1.7-fold and IP2 1.6-fold after 20 and 40 s, respectively.
(7) Short incubations with heparin (5 min) caused a release of the enzyme into the media, while longer incubations caused a 2-8-fold increase in net lipoprotein lipase secretion which was maximal after 2-16 h depending on cell type, and persisted for 24 h. The effect of heparin was dose-dependent and specific (it was not duplicated by other glycosaminoglycans).
(8) The following conclusions emerge: (i) when the 3' or the 3' penultimate base of the oligonucleotide mismatched an allele, no amplification product could be detected; (ii) when the mismatches were 3 and 4 bases from the 3' end of the primer, differential amplification was still observed, but only at certain concentrations of magnesium chloride; (iii) the mismatched allele can be detected in the presence of a 40-fold excess of the matched allele; (iv) primers as short as 13 nucleotides were effective; and (v) the specificity of the amplification could be overwhelmed by greatly increasing the concentration of target DNA.
(9) Epicanthal folds were present in 46%, mongoloid slanting of the lids in 72% of cases.
(10) The estimated DNA compaction ratio (approximately 3-fold) is consistent with a significant degree of nucleosome unfolding in the hyperstimulated BR genes.
(11) Two hours after refeeding rats fasted for 48 h, ODC activity increased 40-fold in mucosa from the intact jejunum and 4-fold in the mucosa of the bypassed segments.
(12) Transfection of the treated DNA into SOS-induced spheroplasts results in an increase in mutagenesis as great as 50-fold.
(13) ACh released from the vesicular fraction was about 100-fold more than could be accounted for by miniature end-plate potentials; possible causes of this overestimate are discussed.
(14) In strains completely deleted for galR, the gene which encodes the Gal repressor, the operon is derepressed by only 10-fold without an inducer.
(15) The amount of water, creatinine, electrolytes, proteins, and enzymes were higher during the day (up to three fold, p always less than 0.05), while equal amounts of amino acids were excreted in the day and the night period.
(16) TNBS reacts to an extremely small extend with hemoglobin over the concentration range 0.4 to 4 mM whereas FDNB reacts with hemoglobin to a very large extent (50 fold more than TNBS).
(17) Rates of PC in vitro metabolism by liver and kidney cytosolic cysteine conjugate beta-lyases (beta-lyases) were similar, but metabolism by renal mitochondrial beta-lyase occurred at a 3-fold higher rate than the rate obtained with hepatic mitochondrial beta-lyase.
(18) Dietary factors affect intestinal P450s markedly--iron restriction rapidly decreased intestinal P450 to beneath detectable values; selenium deficiency acted similarly but was less effective; Brussels sprouts increased intestinal AHH activity 9.8-fold, ECOD activity 3.2-fold, and P450 1.9-fold; fried meat and dietary fat significantly increased intestinal EROD activity; a vitamin A-deficient diet increased, and a vitamin A-rich diet decreased intestinal P450 activities; and excess cholesterol in the diet increased intestinal P450 activity.
(19) On the other hand, if we correct for the population of HMM with degraded light chain 2, the difference in the binding constants in the presence and absence of Ca2+ may be as great as 5-fold.
(20) The gene, which is located at chromosome XIII, is transcribed as a mRNA of about 2.7 kilobases, and the amount of message has been found to increase 3- to 4-fold during the culture.
Folder
Definition:
(n.) One who, or that which, folds; esp., a flat, knifelike instrument used for folding paper.
Example Sentences:
(1) To expedite the development of a personal library data base by medical students, we created MEDFILE, a preprinted, cross-indexed file folder system for organizing the medical literature.
(2) Leafing anxiously through a folder thick with court documentation and witness statements, Painter said he wanted his children returned to his care so they could go back to their old school and the home in which they had grown up.
(3) The Faulkner folder has proved to be optimal, allowing for easy and atraumatic folding and insertion.
(4) Yet to judge by the howls when Apple made the latest album free to download to all of the 800m or so iTunes account holders (by automatically adding it to their “Purchased” folder), there’s nothing the internet hates more than getting music for free.
(5) "7-Zip doesn't place files [inside folders] that were not specified by the user," said Pavlov.
(6) We need to help children in care treasure the objects that tell their life story Read more These books, a cross between photo album, scrapbook and folder, are a statutory requirement for all children going into adoption placements .
(7) This information was then used to design appropriate educational materials, including folders, photographs, flip-charts, and posters.
(8) But Pavlov stressed that it is highly unlikely anyone other than the perpetrator - the person who holds the folder's "passphrase" , or password - will be able to force their way into the encrypted "All7z" folder.
(9) Conversion to A4 folders in the practice provided an opportunity to develop a diagramatic representation of family structure and thus create for each patient a family ;portrait.'
(10) In the runup to the 2001 election campaign he and I spent several anxious hours searching for a mislaid folder containing the entire Labour advertising campaign.
(11) A new concept for filing medical records in general practice is described, based on an A4-size folder; in experimental use in 40 practices doctors were generally in favour of the new system.
(12) Each patient's family is provided with a folder containing detailed information about the patient's current treatment.
(13) Maybe it was back last December, on a trip to Afghanistan, when I saw that the young army officer briefing us had a snapshot of a small boy paper-clipped to his folder.
(14) The ocular lenses were foldable with a forcep (Faulker Folder) and inserted into the eye through a 4 mm incision.
(15) In simple terms, instead of having to create multiple folders to organise documents, users will be able to assign files with multiple tags, which can later be used to search.
(16) But it ended up in the company’s spam folder, so the breach was not discovered until the company was contacted by the Financial Times on Monday, the paper said (£).
(17) These folder variables ranged in nature from quantitative measures of academic performance to demographic information and types of extracurricular activity.
(18) A mysterious encrypted folder released online last week containing a further 220,245 private emails exchanged between climate scientists includes another message from the perpetrator, the Guardian has learned.
(19) She says she keeps the hate mail she's received in an email folder entitled "Do not look", and as a new round has started coming in, she has stuck to this rule.
(20) A procedure for converting the medical record envelopes now used in general practice to an A4-sized record folder is described.