(n.) A holding with the feet; firm standing; that on which one may tread or rest securely; footing.
Example Sentences:
(1) A lfred Ekpenyong knows first hand how tough it can be to find a secure foothold in mainstream society after leaving prison.
(2) If you get a foothold even slightly wrong, it makes the next move feel even harder."
(3) The effects of illegal downloading hit the country particularly early and hard, while legal downloading never got a chance to establish a foothold.
(4) The merger with Pepkor has given the group a foothold in 30 countries with 6,500 stores.
(5) But in 2014, while the presence of probably the greatest player of the 20th century was undoubtedly a unique selling point for the conference, the life of the game in the US has reached a point where the constituency of writers, artists, academics, and students in attendance would doubtless have assembled anyway, as the game gains an increasing foothold in the country.
(6) President Rodrigo Duterte declared martial law across the entire southern region of Mindanao in response to the crisis, which he described as the start of a major campaign by IS to establish a foothold in the Philippines.
(7) He seems to hanker after footholds – a dabble with Scientology has come to an end, and it seems fair to say that the experience has contributed to what he calls his "wounded position".
(8) Yet for the Cosmos, looking to gain their own foothold in a crowded New York sports market about to get even more crowded as New York FC commence play in 2015, and with existing MLS team New York Red Bulls having topped their own regular season standings last year, the association with Pelé is still vital.
(9) They changed their tactics a bit – stretching the pitch quicker and playing into the top third quicker – and we just didn’t quite deal with it early enough to get a foothold in the game.
(10) In a sign of the toughness of the market, US giant Best Buy pulled out of the UK last year after struggling to gain a foothold.
(11) If you think five years ahead about what the most valuable games companies will look like, they’ll need to have a strong foothold not only in the Western markets, but in one or two of the big Asian markets: Japan, Korea and China,” said Paananen.
(12) By guaranteeing a bigger foothold for low-cost carriers at key US airports, this settlement ensures airline passengers will see more competition on non-stop and connecting routes throughout the country," said attorney general Eric Holder.
(13) Signs in the last few minutes that Barca are getting a foothold in this game, though they'll surely need something before half time if their dreams aren't to feel totally futile.
(14) The Ukip leader, Nigel Farage, made a more successful visit during the floods, donning waders to reach stranded residents, and his party is beginning to get a foothold in Somerset.
(15) But the suggestion that Russian hackers may gained at least a foothold in electronic voting systems is likely to add even more pressure to special counsel and congressional investigations.
(16) With Beijing hoping to further cement its foothold in a country viewed as offering the easiest entrance to Europe commercially, Chinese officials are eager to replicate Cosco's business model elsewhere.
(17) 10.55am: Meanwhile, this from Gary Ford: "Lest anyone think that soccer may finally be gaining a foothold in the States, immediately after the US game ESPN's 'Sportscenter' opened with the breaking news that ... a former linebacker who hasn't played for 17 years has been indicted for rape."
(18) At the time, I don't think anyone could have imagined that the BNP would gain a foothold in British politics.
(19) Madrid kept their cool in the face of the storm and, gradually, they chiselled out a foothold.
(20) As young Spanish nurses struggle to gain a foothold in the country’s job market, dozens of recruitment fairs have sprung up to bridge the gap between unemployed healthcare workers in Spain, and the UK, where qualified nurses are in high demand.
Lodgement
Definition:
(n.) See Lodgment.
Example Sentences:
(1) Platelets appear to be involved in tumor cell lodgement, since thrombocytopenia significantly reduces the number of lodged tumor cells.
(2) Increased hemopoietic activity following lodgement, seemed to play an important role for further metastases.
(3) Aspiration of a dental calculus, with lodgement of the calculus in a mainstem bronchus, was identified in a dog after dental prophylaxis.
(4) Six hours after release from treatment with 0.3 mM HU cells were synchronized in the G2 phase of the cell cycle but the consequent increase in cell volume was not responsible for increased metastasis through enhancement of tumour-cell arrest, since lodgement of 51Cr-labelled, HU-treated cells was no greater than that of control cells.
(5) Effective hematopoiesis is thought to be maintained by interplaying between the hematopoietic stem cells (HSC) and their supporting stroma which supply an appropriate environment for HSC lodgement, proliferation and differentiation in the bone marrow.
(6) It was more probable that the sulphated polysaccharides were interfering with the passaging of tumour cells across the capillary wall as heparin significantly inhibited metastasis when injected up to 3 hr after lodgement, and heparin and fucoidan caused a gradual loss of tumour cells from the lung which only became apparent greater than 1 hr following cell lodgement.
(7) The suppressive effect of cytotoxicity of the splenocytes by whole body X-irradiation may thus relate to ensuing metastasis both in the phase of release and intravasation from the primary tumor and in the phase of lodgement and proliferation in the target organ.
(8) Most were probably due to malpositioning resulting in movement through a valve during recording or impingement on the valve cusps or the chordae tendineae or lodgement in the apex of the heart.
(9) Enhancing effect of urokinase on fibrin resolution might promote the local tumor growth and release of tumor cells into the vessels, but interfere with the lodgement of tumor cells in remote organs.
(10) We devised a set of instrument, self-made plastic Ivalon for tailoring the plugs, developed the technique of retrograde aortic angiography to measure the diameter of the ductus, and determined the criteria of definite lodgement of the plug.
(11) Coagulation system and platelets play an important role in the stage of lodgement of tumor cells.
(12) In this report, the influence of 18:2 on specific events of tumor metastasis, namely, lodgement, proliferation and survival, were studied using spontaneous and experimental metastasis assays with line 4526 cells.
(13) The IL 1 and TNF action on EC may play a role in tumor cell lodgement.
(14) Most probably inner bumper lodgement in the terminal ileum is related to its size.
(15) These studies indicate that the increase in lung colony yield after LTI cannot be ascribed to improved intravascular trapping or interstitial lodgement of tumor cells.
(16) Lodgement of tumor cells first cultured in serum of mice fed 18:2 then injected into mice fed 1% 18:2 was not affected.
(17) In thrombocytopenia lodgement was reduced by 47% and hepatic 5-HT levels by 52% in comparison with tumor cell-injected controls.
(18) The lodgement of tumour cells (TCs) is a key event in the development of metastases in distant organs.
(19) Thrombocytopenia or 5-HT blockade decrease the hepatic lodgement of the injected TCs.
(20) These findings suggest an etiologic relationship between pill lodgement and Schatzki's ring in patients without reflux and indicate that different therapy should be employed in these patients.