(1) A total of 28 cell lines were selected for Geneticin - resistance and inoculated into the footpads of syngeneic animals following co-transfection with pSV2neo and genomic DNA, or transfection with plasmid constructs containing neo and the activated Ha-ras oncogene.
(2) Four hundred mice were innouclated in the hind footpads with 10(8) organisms.
(3) The DTH responses were induced by subcutaneous injection of allogeneic epidermal cells (ECs) and were assayed by footpad swelling.
(4) The delayed footpad reaction to CRBC was significantly augmented by treatment with OK-432.
(5) In the second experiment, 2 antisera to mouse NGF were given daily into the footpad for 11 or 12 d; control animals were given normal goat serum.
(6) 1218) induced an increasing infection in the liver, spleen, and lungs of the THXB mice, and the infection eventually spread to the opposite footpad and to the tail skin.
(7) Cellularity and intensity of RNA synthesis in the popliteal lymph nodes of mice treated with different types of antigen injected subcutaneously into the hind footpads were followed.
(8) While the cytotoxicity suppressed in tumor-bearing rats was not restored by levamisole, delayed footpad reaction and antibody production were enhanced as compared with the normal reaction, or were restored to normal levels by levamisole, respectively.
(9) GO is immunogenic and stimulates the formation of large numbers of GOBC in the popliteal lymph nodes after injection with adjuvant into the footpads of mice, but 1-mg doses injected IV or IP are lethal because of its enzymatic activity, which causes hypoglycemia and methemoglobinemia.
(10) When immunized animals were footpad tested with MAN, highly significant delayed-type hypersensitivity (DH) responses were detected.
(11) The kinetics and compartmentalization of this anti-idiotypic responsiveness was studied by vaccinating rats in the hind footpads and monitoring the proliferative reactivity of the draining popliteal lymph node (PLN) and distal cervical lymph node (CLN) cells at various times.
(12) The plateau for growth in the footpads of intact mice occurred 4 months after inoculation, whereas in the thymectomized and thymetocomized plus antilymphocyte serum-treated groups the plateau occurred between months 11 and 12 after inoculation.
(13) Using 13762 carcinoma in F344 rats, and Walker carcinoma in Wistar rats, 20 X 10(6) tumor cells were injected into the footpad, and the ipsilateral popliteal lymph node examined by transmission electron microscopy.
(14) This knowledge was applied to the design of experiments using rats inoculated in the footpads with M. leprae.
(15) Cells from draining lymph nodes of mice sensitized with oxazolone 18 h previously were able to induce contact sensitivity to normal mice when administered in their footpads.
(16) An experimental model of inflammatory eye disease, experimental autoimmune uveitis (EAU), was established by injecting rats in the footpad with S-antigen in complete Freund's adjuvant.
(17) CRF, unlike SEA, SEA glycoproteins, or purified MEG, is incapable of eliciting delayed footpad swelling in egg-sensitized mice or of inducing granulomatous hypersensitivity, when given at amounts equivalent to or higher than MEG by protein or carbohydrate content.
(18) Although in vitro translation experiments with polyA+-RNA from adult tail and footpad epidermis consistently failed to reveal the 70-kDa protein among the translation products, we obtained evidence using a specific cDNA clone that, in vivo, the protein is encoded by a discrete mRNA.
(19) A cytotoxic response to murine cytomegalovirus (MCMV) was obtained by the culture of lymph node cells from mice inoculated with MCMV into both hind footpads 7 days previously.
(20) Compared with the conventional vaccine, this new vaccine caused less swelling in the mouse footpad test.
(n.) The foot of a quadruped having claws, as the lion, dog, cat, etc.
(n.) The hand.
(v. i.) To draw the forefoot along the ground; to beat or scrape with the forefoot.
(v. t.) To pass the paw over; to stroke or handle with the paws; hence, to handle fondly or rudely.
(v. t.) To scrape or beat with the forefoot.
(1) In pentobarbital-anesthetized rats or in perfused hind paw of rats, the potentiation induced by cocaine and tripelennamine was more marked to norepinephrine than to epinephrine, but an inverse relation between norepinephrine and epinephrine was observed in the potentiation by I and II.
(2) Both face and paw receptive fields are unions of a certain set of skin areas called compartments.
(3) At both 24 h and 1 week, the inflamed paw showed pronounced supersensitivity to the antinociceptive action of morphine against noxious pressure.
(4) An actor dressed like one of the polar bears that figure in Coke ads limped up, wearing a prosthesis on one paw, a dialysis bag and tubing.
(5) His shot, though, was pawed on to the inside of the post by David Marshall and it was left to Victor Wanyama to lash the loose ball into the empty net.
(6) In the spinalized preparation, steady-state and nonsteady-state responses have an equal likelihood of emerging from the initial cycles of a paw-shake response, suggesting that regular coupling of joint oscillations is not planned by pattern-generating networks within lumbosacral segments.
(7) The spinal ascending pathways responsible for neuronal ventrobasal (VB) thalamic responses elicited by joint stimulation of the posterior paw were determined in arthritic rats used as a model of experimental pain.
(8) The response was composed of an isometric phase, during which the body weight was shifted from the stimulated limb to the opposite forelimb while the stimulated limb was gently pushed backwards, and a movement phase during which the stimulated paw actually accomplished the placing reaction.
(9) Tiny, tiny... rodents – some soft and grey, some brown with black stripes, in paintings, posters, wallcharts, thumb-tacked magazine clippings and poorly executed crayon drawings, hurling themselves fatally in their thousands over the cliff of their island home; or crudely taxidermied and mounted, eyes glazed and little paws frozen stiff – on every available surface.
(10) Carrageenin-induced inflammatory oedema of the rat paw was considerably inhibited at i.v.
(11) The goalkeeper then had to paw out another Carroll header.
(12) In inflammatory studies, 1-4 showed inhibition of formaldehyde-induced paw swelling (edema).
(13) Hence, Paw was a major determinant of oxygenation, although a PEEP greater than Pflex appeared necessary to optimize oxygenation at a constant Paw.
(14) A comparison has been made between liposome-encapsulated and free indomethacin for their anti-inflammatory activities in the carrageenan paw oedema test in rats, and their inhibitory effect on platelet aggregation induced by adenosine 5-diphosphate (ADP) in-vitro.
(15) Standard 5-member series of weak electro-cutaneous stimulations of the fore-paw were applied in chronic experiments to two dogs with implanted cortical electrodes.
(16) from the 1st to the 3rd day and then each 2nd or 3rd day inhibited paw swelling in adjuvant arthritis of the rat during the time of treatment.
(17) It has been shown that under all types of stimulation the latent periods (LP) of nociceptive reactions of paw licking and tail flick were significantly increased, as compared to baseline level, thus suggesting suppression of the pain sensitivity.
(18) Non-steroidal anti-inflammatory drugs (NSAID) only partially inhibit the hyperalgesia in the inflammation induced by carrageenin in the hind rat paw, one of the most frequently used nociceptive tests.
(19) The models used were (1) carrageenin-induced paw oedema in rats previously depleted of polymorphonuclear cells, (2) carrageenin-induced rat pleurisy and (3) migration of rat peritoneal leucocytes from glass capillary tubes in vitro.
(20) AOA and B-H were markedly effective both in scavenging the reactive oxygen species (ROS) generated and in inhibiting lipid peroxidation; they also significantly reduced both adjuvant- and adriamycin-induced paw oedema in rats.