(n.) The anterior of the three principal divisions of the brain, including the prosencephalon and thalamencephalon. Sometimes restricted to the prosencephalon only. See Brain.
Example Sentences:
(1) We assessed changes in brain water content, as reflected by changes in tissue density, during the early recirculation period following severe forebrain ischemia.
(2) To study these changes more thoroughly, specific monoclonal antibodies of the A and B subunits of calcineurin (protein phosphatase 2B) were raised, and regional alterations in the immunoreactivity of calcineurin in the rat hippocampus were investigated after a transient forebrain ischemic insult causing selective and delayed hippocampal CA1 pyramidal cell damage.
(3) The analogy with infant sleep patterns and results of studies of brain function in narcoleptics suggest that forebrain inhibitory processes are more important in narcoleptic symptomology than is brainstem dysfunction.
(4) Neural plate damage, expressed during a critical period of forebrain development, was evaluated 48 h post-insonation.
(5) This result contraindicates a general permissive-requisite role for forebrain NE for the mammalian brain's plasticity during its critical periods.
(6) Key findings include a progressive degeneration of these cholinergic neurons characterized by the formation of immunoreactively atypical NFT, the loss of intraneuronal lipofuscin, a lack of senile plaque and beta-amyloid deposition within the basal forebrain, and end-stage gliosis without residual extracellular NFT.
(7) The hypothalamus is a most complex part of the CNS having rich interconnections with forebrain, limbic and brainstem structures.
(8) Results suggest that the locomotor activating effects of CRF may be due to an activation of CRF receptors in the ventral forebrain, a region rich in CRF cell bodies and projections.
(9) Sixty days after 5,7-DHT administration, immunoreactive serotonin in the forebrain, particularly the suprachiasmatic nuclei and intergeniculate leaflets, was severely depleted in 16 animals, moderately depleted in four and only slightly affected in four.
(10) Twelve-hour polygraph recordings were made before and at various intervals after basal forebrain damage in a total of eight cats.
(11) Impairments of cognition and memory in AD result from disease of neurons in a number of regions, including brainstem, basal forebrain, amygdala, hippocampus, and neocortex.
(12) Patients with bilateral forebrain disease may commonly manifest the syndrome of pathologic laughing and weeping.
(13) Ovariectomized (OVXed) animals were implanted with chronic cannulas in the basal forebrain.
(14) Thus, neurons of the habenula and interpeduncular nucleus are under the direct and indirect influence of septal neurons within the limbic forebrain circuit.
(15) A detailed description is offered on supply of the nucleus preopticus medialis, lateralis, suprachiasmatis and periventricularis, as well as of the nucleus interstitialis striae criminalis and of the preoptic portion of the medical forebrain bundle.
(16) The regional distribution of forebrain neurons expressing preprocholecystokinin (preproCCK) mRNA was examined using in situ and blot hybridization analysis.
(17) Some LC neurones were activated trans-synaptically by stimulation of those forebrain sites which received axonal projections from LC.
(18) Other antidromically activated neurons in the vasodepressor region may be inhibitory vasomotor cells with a function relatively independent of baroreceptor inputs, or they may be A1 catecholamine neurons, with axons passing through the rostral medulla en route to the forebrain.
(19) Fewer, but still ample numbers, of SP-reactive axons are present also in the ventral tegmental and retrorubral areas of the midbrain tegmentum and in the ventral pallidum of the basal forebrain, but only sparse ME-reactive axons are present in these areas.
(20) 5-HT containing terminals and fibers also were observed in the mesencephalon and appeared to run rostrally in the medial part of the medial forebrain bundle.
Telencephalon
Definition:
Example Sentences:
(1) The telencephalon of teleost fish shows high affinity uptake for D-[3H]aspartate, intermediate levels of GABAergic markers and low levels of cholinergic enzymes.
(2) Numerous CA fibers which are first observed at the level of the preoptic area, ascend through the central zone of the telencephalon and arborize profusely particularly within the medial zone of area dorsalis telencephali.
(3) AR and ER mRNA-containing neurons were widely distributed in the rat brain, with the greatest densities of cells in the hypothalamus, and in regions of the telencephalon that provide strong inputs in the medial preoptic and ventromedial nuclei, each of which is thought to play a key role in mediating the hormonal control of copulatory behavior, as well as in the lateral septal nucleus, the medial and cortical nuclei of the amygdala, the amygdalohippocampal area, and the bed nucleus of the stria terminalis.
(4) Injections of horseradish peroxidase into the telencephalon retrogradely labeled neurons ipsilaterally in various thalamic, preglomerular, and tuberal nuclei, the nucleus of the locus coeruleus (also contralaterally), the superior raphe, and portions of the nucleus lateralis valvulae.
(5) Naloxone-displaceable binding was observed in all regions of the brain, with a density ranking order of cerebellum greater than telencephalon greater than optic tectum greater than hypothalamus greater than brain stem greater than pituitary gland.
(6) The histologic and ultrastructural appearance of the telencephalon of the normal 21-day guinea-pig foetus was described for comparative purposes.
(7) Within the telencephalon, chronic but not acute treatment with T3 or T4 selectively increased dopamine (DA) utilization within the diffuse type of DA nerve terminal systems of the nucleus accumbens.
(8) High-energy radiation bombardment of intact frozen telencephalon resulted in a biphasic inactivation curve for [3H]AMPA binding.
(9) M cells were located at the ventralmost region of the junction between the olfactory bulb and telencephalon, while L cells were scattered more rostrally along the ventromedial surface of the olfactory bulb.
(10) Levels of acetylcholine were significantly elevated in the telencephalon and diencephalon + mesencephalon of rats killed by near-freezing during conditioned suppression of food-reinforced lever pressing, whereas levels of serotonin, dopamine, and norepinephrine were not altered.
(11) Some immunopositive cells were detected in the rostral telencephalon but not caudal to the telencephalon.
(12) Extensive plexuses of TH-positive nerve terminals were found in many parts of the telencephalon, mainly confined to the subcortical and limbic cortical structures.
(13) Areas rich in [3H]-SP binding were located in the ventral telencephalon, in the entire hypothalamic and thalamic region, in the midbrain tegmentum, in the optic tectum, in the valvulla cerebelli and in the medulla oblongata.
(14) The earliest generated cells of the cat's telencephalon that may play a role in the formation of the primary visual cortex are the subject of this study.
(15) The performance of tadpoles and juvenile frogs on a battery of behavioral tests was compared before and after tectotomy, removal of the telencephalon (decerebration), tectotomy in conjunction with decerebration, or before and after a sham operation.
(16) Previous work has shown that aggregate cultures prepared from fetal rat telencephalon and grown in a chemically defined medium offer a useful model to study developmental processes such as myelin synthesis.
(17) Norepinephrine (NE) levels in the hypothalamus and telencephalon of genetically obese mice with the OBOB and DBDB mutations are significantly higher than those of their lean littermates.
(18) We tested the contribution of GABAergic inhibition to the response characteristics of 213 neurons in the auditory telencephalon of chronically prepared nonanesthetized chickens.
(19) Three groups of immunoreactive neurons were identified: the first, in the telencephalon, is a paired group of cells scattered near the two telencephalic ventricles; the second group lies near the preoptic recess; the third group occurs in the ventral wall of the infundibulum.
(20) In the telencephalon, the nucleus of the diagonal band and the medial prefrontal cortex contained retrogradely labelled neurons ipsilateral to the TLD injection site.