(n.) The anterior of the three principal divisions of the brain, including the prosencephalon and thalamencephalon. Sometimes restricted to the prosencephalon only. See Brain.
Example Sentences:
(1) We assessed changes in brain water content, as reflected by changes in tissue density, during the early recirculation period following severe forebrain ischemia.
(2) To study these changes more thoroughly, specific monoclonal antibodies of the A and B subunits of calcineurin (protein phosphatase 2B) were raised, and regional alterations in the immunoreactivity of calcineurin in the rat hippocampus were investigated after a transient forebrain ischemic insult causing selective and delayed hippocampal CA1 pyramidal cell damage.
(3) The analogy with infant sleep patterns and results of studies of brain function in narcoleptics suggest that forebrain inhibitory processes are more important in narcoleptic symptomology than is brainstem dysfunction.
(4) Neural plate damage, expressed during a critical period of forebrain development, was evaluated 48 h post-insonation.
(5) This result contraindicates a general permissive-requisite role for forebrain NE for the mammalian brain's plasticity during its critical periods.
(6) Key findings include a progressive degeneration of these cholinergic neurons characterized by the formation of immunoreactively atypical NFT, the loss of intraneuronal lipofuscin, a lack of senile plaque and beta-amyloid deposition within the basal forebrain, and end-stage gliosis without residual extracellular NFT.
(7) The hypothalamus is a most complex part of the CNS having rich interconnections with forebrain, limbic and brainstem structures.
(8) Results suggest that the locomotor activating effects of CRF may be due to an activation of CRF receptors in the ventral forebrain, a region rich in CRF cell bodies and projections.
(9) Sixty days after 5,7-DHT administration, immunoreactive serotonin in the forebrain, particularly the suprachiasmatic nuclei and intergeniculate leaflets, was severely depleted in 16 animals, moderately depleted in four and only slightly affected in four.
(10) Twelve-hour polygraph recordings were made before and at various intervals after basal forebrain damage in a total of eight cats.
(11) Impairments of cognition and memory in AD result from disease of neurons in a number of regions, including brainstem, basal forebrain, amygdala, hippocampus, and neocortex.
(12) Patients with bilateral forebrain disease may commonly manifest the syndrome of pathologic laughing and weeping.
(13) Ovariectomized (OVXed) animals were implanted with chronic cannulas in the basal forebrain.
(14) Thus, neurons of the habenula and interpeduncular nucleus are under the direct and indirect influence of septal neurons within the limbic forebrain circuit.
(15) A detailed description is offered on supply of the nucleus preopticus medialis, lateralis, suprachiasmatis and periventricularis, as well as of the nucleus interstitialis striae criminalis and of the preoptic portion of the medical forebrain bundle.
(16) The regional distribution of forebrain neurons expressing preprocholecystokinin (preproCCK) mRNA was examined using in situ and blot hybridization analysis.
(17) Some LC neurones were activated trans-synaptically by stimulation of those forebrain sites which received axonal projections from LC.
(18) Other antidromically activated neurons in the vasodepressor region may be inhibitory vasomotor cells with a function relatively independent of baroreceptor inputs, or they may be A1 catecholamine neurons, with axons passing through the rostral medulla en route to the forebrain.
(19) Fewer, but still ample numbers, of SP-reactive axons are present also in the ventral tegmental and retrorubral areas of the midbrain tegmentum and in the ventral pallidum of the basal forebrain, but only sparse ME-reactive axons are present in these areas.
(20) 5-HT containing terminals and fibers also were observed in the mesencephalon and appeared to run rostrally in the medial part of the medial forebrain bundle.
Thalamus
Definition:
(n.) A mass of nervous matter on either side of the third ventricle of the brain; -- called also optic thalamus.
(n.) Same as Thallus.
(n.) The receptacle of a flower; a torus.
Example Sentences:
(1) While the heaviest anterogradely labeled ascending projections were observed to the contralateral ventral posterolateral nucleus of the thalamus, pars oralis (VPLo), efferent projections were also observed to the contralateral ventrolateral thalamic nucleus (VLc) and central lateral (CL) nucleus of the thalamic intralaminar complex, magnocellular (and to a lesser extent parvicellular) red nucleus, nucleus of Darkschewitsch, zona incerta, nucleus of the posterior commissure, lateral intermediate layer and deep layer of the superior colliculus, dorsolateral periaqueductal gray, contralateral nucleus reticularis tegmenti pontis and basilar pontine nuclei (especially dorsal and peduncular), and dorsal (DAO) and medial (MAO) accessory olivary nuclei, ipsilateral lateral (external) cuneate nucleus (LCN) and lateral reticular nucleus (LRN), and to a lesser extent the caudal medial vestibular nucleus (MVN) and caudal nucleus prepositus hypoglossi (NPH), and dorsal medullary raphe.
(2) The hippocampus plays an essential role in the laying down of cognitive memories, the pathway to the frontal lobe being via the MD thalamus.
(3) Neurons containing moderate to high concentrations of ChE reaction product were found in 3 distinct regions of the dorsal thalamus.
(4) Morphological results demonstrated that 30 Gy irradiated animals showed extensive necrosis primarily in the fimbria, which extended into the internal capsule, optic nerve, hippocampus, and thalamus.
(5) The occurrence of paresis or paralysis in ischemic processes strictly situated in the thalamus, however, is discussed: the deficit may be limited to parts of limbs; most often, it is not associated with pyramidal symptomatology; recovery is observed in the hand before the inferior limb.
(6) The presence of gelatinosa neurons projecting to the thalamus emphasizes a point made in earlier reports, that these neurons do not form an homogeneous population.
(7) The existence is therefore proposed of some neural mechanism that controls the higher cerebral function of writing via the thalamus.
(8) To identify the origin of scalp-recorded far-field negativity of short-latency somatosensory evoked potentials to median nerve stimulation (designated N18), direct records were made from the thalamus and ventricular system during 4 stereotaxic and 3 posterior fossa operations.
(9) The neighbouring neocortical areas receive afferents neither from the mediodorsal nucleus of the thalamus nor from the ventral mesencephalic tegmentum; their catecholamine innervation is mainly confined to the superficial layers and appears to be of noradrenergic nature.
(10) The tonic influences were expressed in an increase in the amplitude parameters of the responses of the visual cortex in conditions of the formation in the posterolateral nucleus of the thalamus of a focus of heightened excitability (anode polarization), and their perceptible diminution with potassium depression in this nucleus.
(11) Glutamate-immunoreactive neurons were present throughout the acoustic thalamus, including the regions containing the retrogradely labeled neurons.
(12) Neutral aminopeptidase activity showed a significant decrease in the thalamus and cerebellum with marked (not significant) changes in the hypothalamus, hippocampus, medulla, and occipital cortex.
(13) CT findings of 6 cases with germinoma originating in the basal ganglia and thalamus are reported.
(14) Parkinsonism in the present case may be due to the involvement of multiple neuronal circuits of the extrapyramidal system at the level of the midbrain to the thalamus.
(15) Thus, the possibility of defects at other sites, such as the globus pallidus or thalamus must be considered.
(16) Histochemically the lowered activity of enzymes was localized mainly in the neuropil of: striatum, the Broc's nuclei and rhinencephalon: in the nervous cells of: Ammon's horn, nuclei of thalamus and in neocortex.
(17) Peripheral nerve grafts were inserted into the thalamus in 27 Sprague-Dawley rats.
(18) For the stereotactic treatment of Parkinson's disease, the target is usually located in the thalamus; this point is related to nearby structures (third ventricle).
(19) CT findings of them revealed that the hematomas were large or invaded toward the internal capsule and thalamus.
(20) Background activity recorded extracellularly from three anterior (limbic) nuclei of the thalamus was analyzed in chronic unanesthetized rabbits.