(1) The frequency of rare fragile sites was studied among 240 children in special schools for subnormal intelligence (IQ 52-85).
(2) A total of 13 ascertainments of folate sensitive autosomal fragile sites is observed, of which 10q23 fragility appears to be the most frequent.
(3) The fragile site at 10q25 was expressed in larger proportions of malignant than normal cells.
(4) The green fund contributions already announced (which include a $3bn pledge by the US and a $1.5bn pledge by Japan revealed during the G20 summit) “show very clearly that if we want the emerging countries and the more fragile countries to participate in this global growth, we have to ... support them,” Hollande said.
(5) Direct detection of the mutation enables the identification of fragile X negative normal transmitting males and fragile X negative carrier females.
(6) Tim Potter, managing director of support charity the Fragile X Society , adds that the challenges Tom faces in the film will give "hope and encouragement to many other families".
(7) A case of fragile-X syndrome (the Martin-Bell syndrome) in two male half-sibs from different marriages of their mother was described.
(8) Of the 188 males, 19 were found to have the fragile X syndrome, while the remaining 169 males had no recognizable cause of their mental retardation, including normal chromosomes.
(9) "The world economy remains in a deep recession and its financial system in a fragile condition," King said.
(10) A correlation between specific fragile sites and cancer breakpoints has been suggested raising the question of fragile site expression as a predisposing factor in the occurrence of cancer in some persons.
(11) Taking this into account, we derived equilibrium equations for the fragile X [fra(X)] genotype frequencies.
(12) An 18-year-old mentally retarded male with the Martin-Bell syndrome was fragile X positive.
(13) The problems Europe is having today could have a very real effect on our economy at a time when it's already fragile.
(14) The economics of the scene, she says, are "fragile".
(15) A significant relationship with heritable fragile sites was found in this study.
(16) It is associated with bony fragility, blue sclerae and abnormality of tooth dentin.
(17) The ankylosed spine may be fractured following relatively mild trauma attributable to loss of flexibility and increased fragility from osteoporosis.
(18) Apart from evidence of enhanced lysosomal and peroxisomal fragility, probably secondary to the intracellular oedema, the intracellular organelles investigated in this study were unaffected by the myopathic process.
(19) "The economy is still far too fragile to talk of a sustained recovery in the housing market, but the hope is that we are past the worst," he added.
(20) Of these new DNA markers, 5 lie in an interval defined as containing the fragile X region.
Frail
Definition:
(n.) A basket made of rushes, used chiefly for containing figs and raisins.
(n.) The quantity of raisins -- about thirty-two, fifty-six, or seventy-five pounds, -- contained in a frail.
(n.) A rush for weaving baskets.
(superl) Easily broken; fragile; not firm or durable; liable to fail and perish; easily destroyed; not tenacious of life; weak; infirm.
(superl) Tender.
(superl) Liable to fall from virtue or be led into sin; not strong against temptation; weak in resolution; also, unchaste; -- often applied to fallen women.
Example Sentences:
(1) Variability among frail elders and variability over 30 days within the same person, when factored, also showed nonequivalence.
(2) The objective of this investigation was to determine the frequency of and predictors for inadequate barium enemas in the frail elderly.
(3) To develop a noninvasive clinical predictive model for acute congestive heart failure (CHF) in a frail elderly cohort using bedside clinical assessment (medical history and physical examination) and venous atrial natriuretic peptide (ANP) levels.
(4) 1) Defensively frail England should go for broke Argue about the Danny Rose handball and the charge on Phil Jagielka all you like, but you’ll be dancing on the head of a pin.
(5) Physicians not only need better preparation to meet the challenges of caring for frail older patients, but they also need changes in reimbursement policies so that they can afford to spend the time needed to manage the complexities inherent in the doctor-patient-family caregiver relationship.
(6) Our data demonstrate that frail elderly receiving only acute care do not suffer markedly prolonged total LOS (TLOS).
(7) Her warning comes as figures reveal that regulators are receiving more than 150 allegations of abuse of the frail and elderly every day.
(8) At the opening ceremony of the 2012 Olympic Games in London, he seemed extremely frail and was only able to walk a few steps.
(9) In particular the rapid aging of the Chinese population has prompted official concern about the financial implications of providing health care to increasing numbers of disabled or frail elderly.
(10) In the Lords, the broadcaster Joan Bakewell called on the government to take "the most urgent steps" to relieve the suffering of neglected old and frail people.
(11) One hundred-seventeen subjects 65 years of age and over, meeting eligibility criteria to target frail older persons with changing medical and social needs, were randomly assigned to receive a comprehensive geriatric assessment by a multidisciplinary team (treatment) or by one of a panel of community internists who were reimbursed according to their usual and customary fee (controls).
(12) In a statement, the chief medical officer, Professor Dame Sally Davies, said: "Severe winter flu and its complications can make people really ill and can kill, particularly those who are weak and frail which is why we already offer vaccinations to the most at risk groups.
(13) Endoscopic intervention is a valuable alternative for the removal of retained stones or in frail patients not fit for general anaesthesia.
(14) Photograph: AFP Saint Laurent became an object of immediate fascination: quiet, timid, with neatly parted schoolboy hair, anxious eyes lurking behind thick glasses and a frail body encased in a tight black suit.
(15) One minute the Führer was so frail he could barely stand up.
(16) Rugi arranged for Katadia’s father to phone at a time when she would be in the zone to facilitate and hold the phone to the ear of his frail little daughter.
(17) Concerning household composition this study showed that frail elderly living alone and residents of old people's homes had significantly more depressive complaints than frail elderly living with others and independently living frail elderly respectively.
(18) There are fewer signs that Erdoğan’s designation of half the Turkish population as congenitally frail and incompetent, such as to recall apartheid if the target were another race, is regarded as utterly incompatible with accession.
(19) He was so thin and frail, but he was able to conduct.
(20) Frail patients died in hospital not from their primary illness but from the staphylococcus infection they picked up there, which the antibiotic methicillin was no longer able to treat because the bacteria had become resistant to the drug as a result of overuse.