(1) The frequency of rare fragile sites was studied among 240 children in special schools for subnormal intelligence (IQ 52-85).
(2) A total of 13 ascertainments of folate sensitive autosomal fragile sites is observed, of which 10q23 fragility appears to be the most frequent.
(3) The fragile site at 10q25 was expressed in larger proportions of malignant than normal cells.
(4) The green fund contributions already announced (which include a $3bn pledge by the US and a $1.5bn pledge by Japan revealed during the G20 summit) “show very clearly that if we want the emerging countries and the more fragile countries to participate in this global growth, we have to ... support them,” Hollande said.
(5) Direct detection of the mutation enables the identification of fragile X negative normal transmitting males and fragile X negative carrier females.
(6) Tim Potter, managing director of support charity the Fragile X Society , adds that the challenges Tom faces in the film will give "hope and encouragement to many other families".
(7) A case of fragile-X syndrome (the Martin-Bell syndrome) in two male half-sibs from different marriages of their mother was described.
(8) Of the 188 males, 19 were found to have the fragile X syndrome, while the remaining 169 males had no recognizable cause of their mental retardation, including normal chromosomes.
(9) "The world economy remains in a deep recession and its financial system in a fragile condition," King said.
(10) A correlation between specific fragile sites and cancer breakpoints has been suggested raising the question of fragile site expression as a predisposing factor in the occurrence of cancer in some persons.
(11) Taking this into account, we derived equilibrium equations for the fragile X [fra(X)] genotype frequencies.
(12) An 18-year-old mentally retarded male with the Martin-Bell syndrome was fragile X positive.
(13) The problems Europe is having today could have a very real effect on our economy at a time when it's already fragile.
(14) The economics of the scene, she says, are "fragile".
(15) A significant relationship with heritable fragile sites was found in this study.
(16) It is associated with bony fragility, blue sclerae and abnormality of tooth dentin.
(17) The ankylosed spine may be fractured following relatively mild trauma attributable to loss of flexibility and increased fragility from osteoporosis.
(18) Apart from evidence of enhanced lysosomal and peroxisomal fragility, probably secondary to the intracellular oedema, the intracellular organelles investigated in this study were unaffected by the myopathic process.
(19) "The economy is still far too fragile to talk of a sustained recovery in the housing market, but the hope is that we are past the worst," he added.
(20) Of these new DNA markers, 5 lie in an interval defined as containing the fragile X region.
Structure
Definition:
(n.) The act of building; the practice of erecting buildings; construction.
(n.) Manner of building; form; make; construction.
(n.) Arrangement of parts, of organs, or of constituent particles, in a substance or body; as, the structure of a rock or a mineral; the structure of a sentence.
(n.) Manner of organization; the arrangement of the different tissues or parts of animal and vegetable organisms; as, organic structure, or the structure of animals and plants; cellular structure.
(n.) That which is built; a building; esp., a building of some size or magnificence; an edifice.
Example Sentences:
(1) The findings indicate that there is still a significant incongruence between the value structure of most family practice units and that of their institutions but that many family practice units are beginning to achieve parity of promotion and tenure with other departments in their institutions.
(2) The influence of the various concepts for the induction of lateral structure formation in lipid membranes on integral functional units like ionophores is demonstrated by analysing the single channel current fluctuations of gramicidin in bimolecular lipid membranes.
(3) We have determined the genomic structure of the fosB gene and shown that it consists of 4 exons and 3 introns at positions also found in the c-fos gene.
(4) Structure assignment of the isomeric immonium ions 5 and 6, generated via FAB from N-isobutyl glycine and N-methyl valine, can be achieved by their collision induced dissociation characteristics.
(5) The fine structure of neurofibrillary tangles in the hippocampal gyrus, substantia nigra, pontine nuclei and locus coeruleus of the brain was postmortem studied in a case of progressive supranuclear palsy.
(6) Life expectancy and the infant mortality rate are considered more useful from an operational perspective and for comparisons than is the crude death rate because they are not influenced by age structure.
(7) It has been generally believed that the ligand-binding of steroid hormone receptors triggers an allosteric change in receptor structure, manifested by an increased affinity of the receptor for DNA in vitro and nuclear target elements in vivo, as monitored by nuclear translocation.
(8) Immunocytochemistry was used to visualize cytoskeletal structures and to assay selective disruption of neurofilaments by acrylamide.
(9) The quaternary structure of ribonucleotide reductase of Escherichia coli was investigated, with the use of purified B1 and B2 proteins and bifunctional cross-linking agents.
(10) Structural peculiarities in tubulin polymorphism are considered.
(11) We report a series of experiments designed to determine if agents and conditions that have been reported to alter sodium reabsorption, Na-K-ATPase activity or cellular structure in the rat distal nephron might also regulate the density or affinity of binding of 3H-metolazone to the putative thiazide receptor in the distal nephron.
(12) It is likely that trunk mobility is necessary to maintain integrity of SI joint and that absence of such mobility compromises SI joint structure in many paraplegics.
(13) Fluorination with [18F]acetylhypofluorite yields 6-[18F]fluoro-L-dopa with 95% radiochemical purity; fluorination of the same substrate with [18F]F2 yields a mixture of all three structural isomers in a ratio of 70:16:14 for 6-, 5-, and 2-fluoro compounds.
(14) But the wounding charge in 2010 has become Brown's creation of a structural hole in the budget, more serious than the cyclical hit which the recession made in tax receipts, at least 4% of GDP.
(15) The aetiological factors concerned in the production of paraumbilical and epigastric hernias have been reviewed along structural--functional lines.
(16) The disassembly of the synthetase complex is consistent with the structural model of a heterotypic multienzyme complex and suggests that the complex formation is due to the specific intermolecular interactions among the synthetases.
(17) In addition to the phase diagrams reported here for these two binary mixtures, a brief theoretical discussion is given of other possible phase diagrams that may be appropriate to other lipid mixtures with particular consideration given to the problem of crystalline phases of different structures and the possible occurrence of second-order phase transitions in these mixtures.
(18) The structures of 1 and 2 were established mainly on the basis of nmr spectroscopic data.
(19) Determination of the primary structure for factor V has provided the basis for examination of structure-function relationships.
(20) Aside from these characteristic findings of HCC, it was important to reveal the following features for the diagnosis of well differentiated type of small HCC: variable thickening or distortion of trabecular structure in association with nuclear crowding, acinar formation, selective cytoplasmic accumulation of Mallory bodies, nuclear abnormalities consisting of thickening of nucleolus, hepatic cords in close contact with bile ducts or blood vessels, and hepatocytes growing in a fibrous environment.