(v. t.) A part broken off; a small, detached portion; an imperfect part; as, a fragment of an ancient writing.
Example Sentences:
(1) The nucleotide sequence of a 2.2-kb DNA fragment which contains the complete RAD7 gene was determined.
(2) In the second approach, attachment sites of DTPA groups were directed away from the active region of the molecule by having fragment E1,2 bound in complex, with its active sites protected during the derivatization.
(3) The Fc fragment of this protein reacted with and was solubilized by the staphylococcal A protein which also precipitated the intact immunoglobulin.
(4) In order to determine the extent of this similarity, I have developed a panel of probes for many of the Pacl restriction fragments and have shown that most of the Pacl and Notl fragments found in MBa are also present in MBb.
(5) Under milder trypsin digestion conditions three resistant fragments were produced from the free protein.
(6) Five of them had a fast-moving Eco RI fragment 5.6 kb long that hybridized with zeta-specific probe but not with alpha-specific probe.
(7) Comparative data for the fragments from RNAs 1, 2, and 3 show that they have nearly the same sequence as the RNA 4 fragment.
(8) A sperm whale myoglobin gene containing multiple unique restriction sites has been constructed in pUC 18 by sequential assembly of chemically synthesized oligonucleotide fragments.
(9) Urine specimens from patient REE also contained a light chain fragment that lacked the first (amino-terminal) 85 residues of the native light chain but otherwise was identical in sequence to the light chain REE.
(10) Northern hybridization analysis of R. toruloides RNA with a restriction fragment encoding part of the PAL gene indicates that PAL mRNA is 2.5 kilobases in length.
(11) The method of sonicating L3 and Mf fragment antigens used in this study is simple, and its results are easy to observe.
(12) Benzyloxycarbonylarginine p-nitrophenyl ester and other activated esters of N-a-sustituted arginine salts may be useful reagents for introduction of trypsin-labile protecting groups into peptide fragments for purpose of polypeptide semi-synthesis.
(13) The 6.6-kb DNA Bam HI fragment containing the resistance gene was cloned with the plasmid vector pIJ699.
(14) It was found that these Hageman factor fragments promoted rapid proteolysis of one-chain factor VII to a more active two-chain form.
(15) Restriction fragment length polymorphisms (RFLPs) were studied in a large Algerian family which includes 6 haemophiliacs and a previously described case of female haemophilia A.
(16) A 2.7-kilobase DNA fragment carrying the entire exotoxin A (ETA) structural gene was divided into three nonoverlapping probes.
(17) A 6.4 kilobase C4B-5'-specific Taq I fragment usually provided a reliable guide to the presence of a C4A deletion but unusually in one instance this fragment was found to be a marker of a functioning C4A gene.
(18) The method involves the use of a monoclonal antibody fragment mixture that binds to platelets.
(19) Three distinct antigenic regions of bovine somatotropin (bST) were identified on the basis of the ability of a set of monoclonal antibodies to bind to proteolytic fragments and deletion variants of recombinant bST (rbST) in Western blot analyses.
(20) The coding sequence for Spirulina platensis acetohydroxy acid synthase (AHAS, EC 4.1.3.18) is shown to be contained within a 4.2 Kb ClaI fragment (ilvX) that has been cloned from a recombinant lambda library.
Friable
Definition:
(a.) Easily crumbled, pulverized, or reduced to powder.
Example Sentences:
(1) High-grade left mainstem bronchial obstruction was caused by friable granulation tissue secondary to an underlying foreign body.
(2) As for group I specifically, colonic ulcerations due to Cytomegalovirus were present in all the patients, varying from punctate and superficial erosions to deep ulcerations, with granular and friable intervening mucosa.
(3) A 65-year-old woman experienced transient paralysis of the left arm immediately after palpation of the right carotid artery; at surgery, a friable, atherosclerotic plaque was removed from the bifurcation of the artery.
(4) Thus, the skin appears to develop a relative oxygen debt during CPB which may decrease the threshold for skin injury particularly in older patients who may have other predisposing factors, such as obesity, generalized atherosclerosis, diabetes, or friable skin.
(5) On proctoscopic examination, discrete 2- to 5-mm raised plaques are seen adherent ot an edematous, friable mucosa.
(6) Rhinosporidiosis most commonly involves the nose, and presents as a friable papillomatous mass causing nasal obstruction, epistaxis, purulent discharge, and headache may also occur.
(7) Brinase added to human plasma in vitro caused a decrease in fibrinogen concentration, positive paracoagulation tests and formation of a friable clot in sequence.
(8) In normal bowel segment this may not pose a problem, but forceful attempts at eversion in diseased, thickened, and friable bowel may result in damage to the bowel segment.
(9) Steely hair disease, a neurodegenerative disorder, is characterized by slow growth, progressive cerebral dysfunction, kinky friable hair, x-linked inheritance, and death before three years of age.
(10) The presence of phosphates makes oral medical treatment ineffective, but mixed stones are more friable than pure cystine stones and are therefore easier to treat by extracorporeal lithotripsy.
(11) Although friable callus was obtained from ovary tissue cultured on a medium containing 2 mg per 1 (11 micrometer) naphthaleneacetic acid and 4 mg per 1 (18 micrometer) BAP, it produced shoots after 8 weeks of further subculture on the same medium.
(12) Clustering of largely immobile food resources and friable soils appear to be the major factors influencing chrysochlorid distribution.
(13) The liver was large, friable, and gun-metal blue, with microscopically evident hepatocyte dissociation, degeneration, and necrosis.
(14) Two peaks of activity were observed, when DNP-Gly-Gly-Ile-Arg was used as a substrate, one of them being correspondent to prevalence of dense colonies in the culture and the other to the prevalence of friable networks of hyphae.
(15) Repeated passage of the nasopharyngeal airway and nasotracheal tube over relatively friable nasal mucosa accounted for increased hemorrhage in the dilated group.
(16) Scanning electron microscopy showed that OpaC- and OpaD-containing variants yielded greater mucosal damage than OpaB-containing and Opa- variants with the least damage caused by the OpaA-containing variant (clumped bacteria from dark opaque friable colonies).
(17) Friable vegetation was attached to the auricular surface of the mitral valve.
(18) In elk 3, several of the large muscles of the hindlimbs as well as the biceps brachii muscles of the forelimbs appeared pale, dry, and friable.
(19) The gastric mucosa was erythematous, friable, and bile stained, and the histology revealed chronic inflammation.
(20) Craniotomy showed a tender, friable tumor with a yellowish cyst fluid, but apparently not invading the brain parenchyma.