(v. t.) A part broken off; a small, detached portion; an imperfect part; as, a fragment of an ancient writing.
Example Sentences:
(1) The nucleotide sequence of a 2.2-kb DNA fragment which contains the complete RAD7 gene was determined.
(2) In the second approach, attachment sites of DTPA groups were directed away from the active region of the molecule by having fragment E1,2 bound in complex, with its active sites protected during the derivatization.
(3) The Fc fragment of this protein reacted with and was solubilized by the staphylococcal A protein which also precipitated the intact immunoglobulin.
(4) In order to determine the extent of this similarity, I have developed a panel of probes for many of the Pacl restriction fragments and have shown that most of the Pacl and Notl fragments found in MBa are also present in MBb.
(5) Under milder trypsin digestion conditions three resistant fragments were produced from the free protein.
(6) Five of them had a fast-moving Eco RI fragment 5.6 kb long that hybridized with zeta-specific probe but not with alpha-specific probe.
(7) Comparative data for the fragments from RNAs 1, 2, and 3 show that they have nearly the same sequence as the RNA 4 fragment.
(8) A sperm whale myoglobin gene containing multiple unique restriction sites has been constructed in pUC 18 by sequential assembly of chemically synthesized oligonucleotide fragments.
(9) Urine specimens from patient REE also contained a light chain fragment that lacked the first (amino-terminal) 85 residues of the native light chain but otherwise was identical in sequence to the light chain REE.
(10) Northern hybridization analysis of R. toruloides RNA with a restriction fragment encoding part of the PAL gene indicates that PAL mRNA is 2.5 kilobases in length.
(11) The method of sonicating L3 and Mf fragment antigens used in this study is simple, and its results are easy to observe.
(12) Benzyloxycarbonylarginine p-nitrophenyl ester and other activated esters of N-a-sustituted arginine salts may be useful reagents for introduction of trypsin-labile protecting groups into peptide fragments for purpose of polypeptide semi-synthesis.
(13) The 6.6-kb DNA Bam HI fragment containing the resistance gene was cloned with the plasmid vector pIJ699.
(14) It was found that these Hageman factor fragments promoted rapid proteolysis of one-chain factor VII to a more active two-chain form.
(15) Restriction fragment length polymorphisms (RFLPs) were studied in a large Algerian family which includes 6 haemophiliacs and a previously described case of female haemophilia A.
(16) A 2.7-kilobase DNA fragment carrying the entire exotoxin A (ETA) structural gene was divided into three nonoverlapping probes.
(17) A 6.4 kilobase C4B-5'-specific Taq I fragment usually provided a reliable guide to the presence of a C4A deletion but unusually in one instance this fragment was found to be a marker of a functioning C4A gene.
(18) The method involves the use of a monoclonal antibody fragment mixture that binds to platelets.
(19) Three distinct antigenic regions of bovine somatotropin (bST) were identified on the basis of the ability of a set of monoclonal antibodies to bind to proteolytic fragments and deletion variants of recombinant bST (rbST) in Western blot analyses.
(20) The coding sequence for Spirulina platensis acetohydroxy acid synthase (AHAS, EC 4.1.3.18) is shown to be contained within a 4.2 Kb ClaI fragment (ilvX) that has been cloned from a recombinant lambda library.
Sequestrum
Definition:
(n.) A portion of dead bone which becomes separated from the sound portion, as in necrosis.
Example Sentences:
(1) The second case concerns a 11 year-old boy who, after having complained from pain of the right wrist during 2 weeks, presented with swelling and on X-ray films a picture of metaphyso-epiphyseal lysis and an aspect of sequestrum in its center.
(2) After platinectomy and excision of a bony sequestrum, there remained only a large fossa with an area equivalent to 3 times that of a usual fenestra ovale.
(3) Direct local thrombolysis with low-dose Urokinase resulted in partial recanalisation with an excellent clinical result despite the persistence of an endovenous sequestrum situated at the catheter tip, a sequela of previous thrombosis.
(4) This may be explained by a different condition of the adipocytes in the sequestrum.
(5) The retained eruption sequestrum may lead to pericoronitis or pit and fissure caries.
(6) Unlike a simple fungus ball (the saprophytic form of aspergillosis), the rounded density of invasive pulmonary aspergillosis consists of sequestrum of devitalized lung tissue owing to blood vessel invasion by Aspergillus hyphae.
(7) The most frequent pulmonary cysts in this series were the bronchogenic and patients with parasitic cysts, lobe emphysema and pulmonary sequestrum were excluded.
(8) A slight loss of crestal alveolar bone occurred in the experimental areas and a bone sequestrum formed in one instance.
(9) Complications included skin loss (5 horses), laminitis of the affected limb (2 horses), laminitis of the contralateral limb (4 horses), osteomyelitis and sequestrum formation (2 horses), and bacteremia (1 horse).
(11) A case of osteomyelitis with a typical sequestrum of the alveolar bone, occurred three months after the extraction of the corresponding tooth, is reported.
(12) In Patient 1, septic arthritis and juxta-articular osteomyelitis with sequestrum formation were demonstrated by CT four weeks before abnormalities were shown on a roentgenogram.
(13) The only role of surgery is incision and drainage of a post-auricular abscess and removal of sequestrum if present.
(14) Sequestrectomy should be reserved for cases where a sequestrum and adequate involucrum can be seen on X-ray.
(15) Protein concentration was determined, using the Bradford technique, in tears from cats with normal corneas and from cats with corneal sequestrum.
(16) Two patterns occur: a localized involvement of the tympanic plate which resolves after the spontaneous separation of a sequestrum of bone, and a more diffuse necrosis of the temporal bone with a high risk of involvement of adjacent structures, in particular the brain, labyrinth and facial nerve and to a lesser extent the temporomandibular joint and the parotid gland.
(17) On the border between the two areas hypervascularity produces a zone of fragility where microfractures develop with detachment of a sequestrum.
(18) The radiographs may demonstrate an eggshell appearance, a sequestrum, marked sclerosis, or cystic changes.
(19) In most cases, SI analysis of nonenhanced T1- and T2-weighted images allows the differentiation of hypervascularized viable tissue from hypovascularized necrotic tissue of the sequestrum.
(20) The infant presented with Livedo reticularis and an ulcer on the right forearm since birth; the underlying radius and ulna showed osteomyelitic changes with sequestrum formation and a pathological fracture.