(1) In agreement with reports from comparable centres, metals are high up on the "hitlist" of frequent allergens (nickel 24%, cobalt 9%, chromates 6%), followed by ingredients of cosmetics and toiletries (fragrances 16%, balsam of Peru 10%, Kathon 5%), whilst already way back are topical medicines (neomycin 4%, parabens 3%, lanolin 2%, benzocaine 1%) and rubber additives (thiuram-mix 2% and carba-mix 1%).
(2) The most frequent contact allergens were paraphenylenediamine dihydrochloride (16%), followed by fragrance mix (15%), and nickel sulfate (13%).
(3) The aromatherapeutical use of commercial valerian root oil (Chinese origin) and of pure fragrance compounds--borneol, isoborneol, bornyl acetate (main constituent of the proved valerian root oil) and isobornyl acetate--as potentially drugs with sedative effects after inhalation was investigated in an animal experiment (mice).
(4) Among the spices, the highest numbers of reactions were found to nutmeg (28%), paprika (19%) and cloves (12%) in the indicator-positive Group I. Fragrance-mix turned out to be a particularly important indicator allergen, especially for paprika, nutmeg and cloves.
(5) Carcinogenesis studies of benzyl acetate (a fragrance and flavoring agent) were conducted in F344 rats and B6C3F1 mice.
(6) Sensitization dose-response curves were developed for cinnamaldehyde (CINN) and a complex fragrance mixture, F-16.
(7) Patch test reactions to nickel sulphate, Kathon CG and fragrance-mix occurred more frequently in patients with eyelid dermatitis than in those without.
(8) Currently, d-limonene is widely used as a flavor and fragrance and is listed to be generally recognized as safe (GRAS) in food by the Food and Drug Administration (21 CFR 182.60 in the Code of Federal Regulations).
(9) Dietary anticarcinogens are found in minute amounts in many fruits and vegetables and often are the flavor and fragrance components that characterize them.
(10) Benzylideneacetone is first separated from other fragrance ingredients by LC and then reacted post-column with a methanolic solution of isonicotinic acid hydrazide and aluminum nitrate.
(11) 3 (R-3) and to evaluate the assessments sent to FDA as part of the petitions for use of the colors for drug and external uses by the Cosmetic, Toiletry and Fragrance Association (CTFA).
(12) The other fragrance, isoeugenol (ISOE), and fragrance mixtures, F-07 and F-22, were also found to be weak sensitizers in the MESA and vit A MESA.
(13) He saw the label flourish throughout the 2000s, releasing women's and men's ready-to-wear collections as well as accessories, eyewear and two fragrances.
(14) GB Burlotto Barolo Monvigliero, Piedmont, Italy 2008 (£28, The Wine Society ) This has the classic barolo paradox of power (14.5% alcohol) and ethereal fragrance (rose floral and subtle earthiness), but there's a ripeness and generosity of fruit here that you don't always find in nebbiolo at this age: a treat for wild mushroom risotto or pulse-based stews.
(15) The best way to extract the flavour is to steep the tea in hot butter or milk, which will then infuse the entire bake with the tea's fragrance.
(16) Vegaolmosponce's idea was that you could mix two Lynx fragrances to get a third and that in turn would help men attract a gorgeous "mixable" woman.
(17) Flagship Alexander McQueen stores opened in New York, London and Milan, and the designer released a number of fragrances and, in 2006, a ready-to-wear line called McQ that is now distributed in 39 countries.
(18) Chromatograms taken before and after microencapsulation of two commercial fragrances are discussed.
(19) 2 different groups of patients were patch tested with 2 test series (A and B) containing extracts of fragrance raw materials, traditionally used in Indonesian cosmetics.
(20) 179 patients suspected of cosmetic allergy were patch tested with a series of 16 fragrance materials and 9 preservatives.
Heliotrope
Definition:
(n.) An instrument or machine for showing when the sun arrived at the tropics and equinoctial line.
(n.) A plant of the genus Heliotropium; -- called also turnsole and girasole. H. Peruvianum is the commonly cultivated species with fragrant flowers.
(n.) An instrument for making signals to an observer at a distance, by means of the sun's rays thrown from a mirror.
(n.) See Bloodstone (a).
Example Sentences:
(1) On admission, there were diffuse edema of upper eyelids with heliotrope rash.
(2) By the end of the second year 12% (14 of 120) of the sheep had died; after 4 years the loss attributable to heliotrope was between 18% and 35%.
(3) Juvenile dermatomyositis is a chronic disease of childhood that is manifested by severe symmetrical progressive muscle weakness, a characteristic heliotrope colored skin rash which involves the face, and by elevated serum enzymes related to muscle damage.
(4) Feeding heliotrope alone induced the histological changes of pyrrolizidine alkaloid toxicity in the liver, but this was not associated with an excessive accumulation of copper or the development of clinical illness.
(5) The relatively low mortality from primary heliotrope poisoning and the low concentration of copper in the liver of sheep grazing the plant are discussed in relation to the contrasting situation that prevails in the Riverina area of New South Wales.
(6) A 57-year-old man developed polyarthralgia, muscle weakness, heliotrope rash and Gottron's sign.
(7) The 10 sheep fed heliotrope alone did not show signs of clinical illness but one died and was found to have severe liver damage.
(8) The effects of interrupting the enterohepatic circulation (EHC) of bile salts for seven hours and of feeding copper and heliotrope alone and combined for 13 weeks, on bile flow and excretion of copper, zinc, iron and alpha-mannosidase were studied in sheep.
(9) Two middle-aged women showed typical erythematous heliotrope eruption and Gottron's sign without any symptom of myositis.
(10) This paper contributes one case of paraneoplastic dermatomyositis associated to infiltrant vesical tumour, presenting erythematous damage in face, nape of the neck and upper thorax, as well as periorbital heliotrope erythema and fingernails base and sides telangiectasia, all of which are typical signs of dermatomyositis.
(11) In a field experiment in the Mallee district of Victoria, Merlno xBorder Leicester ewes and wethers grazed Heliotropium europaeum (heliotrope) over periods of 3 to 4 months in 4 successive years.
(12) Biliary concentration of copper correlated with alpha-mannosidase's activity in control sheep and those given copper or heliotrope, supporting the hypothesis that lysosomes are involved in biliary secretion of copper in sheep.
(13) Wodehouse's correspondence is often clad in the epistolary equivalent of Bertie's heliotrope pyjamas, carefully buttoned up to disguise true feeling.
(14) The importance of local environmental factors in the management of heliotrope grazing by sheep is emphasised, particularly in relation to the number of seasons in which the plant may be a major component of the diet.
(15) The concentrations of copper in the livers of control and heliotrope-treated sheep, were comparable.
(16) Physical examination showed Gottron's papules on her fingers and a faint heliotrope rash.
(17) In one experiment copper and heliotrope were given concurrently, in a second experiment heliotrope was fed for 12 weeks and copper administration commenced 8 weeks later.
(18) Copper output was lower when heliotrope was fed alone.