(v. t.) A small yellowish or brownish spot in the skin, particularly on the face, neck, or hands.
(v. t.) Any small spot or discoloration.
(v. t.) To spinkle or mark with freckle or small discolored spots; to spot.
(v. i.) To become covered or marked with freckles; to be spotted.
Example Sentences:
(1) The authors conclude the sun-induced freckles in the young may consist of a hyperplasia of melanocytes (i.e., similar to solar lentigines in the elderly), sometimes with cellular atypia, and that these findings may be relevant to melanocytic neoplasia.
(2) The patient had mild clinical symptoms consisting of numerous pigmented freckles and a small number of seborrheic keratosis-like papules.
(3) A 43-year-old man with xeroderma pigmentosum, XP97TO, was allocated to complementation group D. He had had moderate photosensitivity at age 1 year and freckles by age 6 but no neurologic abnormalities.
(4) The patient had manifested moderate solar sensitivity and freckles by the age of 6 years.
(5) Clinical manifestation of neurofibromatosis include multiple cafe-au-lait spots, axillary freckles, congenital glaucoma, relative macrocephaly, radiologic findings of overtubulation of the long bones, and precocious puberty.
(6) Recognition of mucosal freckling around the appendiceal orifice helps identify the cecum and may be useful in the evaluation of cecal and appendiceal pathology.
(7) Freckling was positively correlated with higher counts; the severe freckling group had an estimated ratio of 1.9 (95% CI 1.3-2.8) compared with those with no or very few freckles.
(8) The index of agreement (calculated as the intra-class correlation coefficient) was 59.7% and 69.0% for freckling on the right forearm and on the shoulders, respectively; agreement was above 50% for only one of six pairs of clinicians in examining freckling on the right forearm, while agreement was above 50% for four of the six pairs of clinicians in examination of freckling on the shoulder.
(9) While my pink, freckled body is blank and pictureless, my father's is an ink-splattered historical document.
(10) And, yes, he could also look splendidly odd, with his windbeaten thatch of sandy hair, porcine eyes and a freckled face that would glow puce and glossy with rage.
(11) "Sure, there's no time limit," a red-haired freckled-faced teenager had told us as she showed Rex and me to our bedsit-sized cubicle.
(12) In 508 students the burning-tanning histories were compared with eye and hair color, freckling tendency, and number of moles.
(13) Computerized image analysis was used to compare lentigines (brown freckle-like cutaneous spots) induced by treatment with psoralens and ultraviolet light A (PUVA-induced lentigines) with those induced by solar exposure (actinic lentigines).
(14) It may have been, in part, an artefact due to increased recognition of Hutchinson's melanotic freckle in this sub-group of the population.
(15) Focused and defocused modes were applied to various lesions ranging from cysts to freckles.
(16) With the job all but done, Mayweather slid and ran, Alvarez kept lunging, his allotted time now down to three minutes, the frustration painted on his freckled face.
(17) In childhood the incidence of IH exceeds that of cutaneous neurofibromas and axillary freckling.
(18) This means that phenotypic characters suggest low MED values only in individuals with red hair, blue eyes and many freckles.
(19) In 15% of these the histogenetic pattern of Hutchinson's melanotic freckle could be observed in the epidermis, adjacent to the invasive melanoma.
(20) Additionally, children with freckles have higher mean nevus count in every category of skin complexion.
Lentigo
Definition:
(n.) A freckly eruption on the skin; freckles.
Example Sentences:
(1) The epidermis covering the tumor node is infiltrated by some tumor cells but the characteristic alterations as described above for the various stadia of lentigo maligna are no longer visible.
(2) The consistency of this classification was tested by two Brisbane pathologists who indicated that we had misinterpreted some cases of superficial spreading malignant melanoma as lentigo maligna melanoma.
(3) This report documents the development of multiple cutaneous tumors, including squamous cell carcinoma, basal cell carcinoma, actinic keratoses, keratoacanthomas, and one case of lentigo maligna, in seven patients who received topical therapies for mycosis fungoides.
(4) Lentigo maligna is a precancerosis or a melanoma in situ, whose level of malignancy has not yet been definitively clarified.
(5) Ultrastructural examination of tissue from the neoplasm showed a well-developed protein framework similar in appearance to that seen in the slowly progressive lentigo maligna form of malignant melanoma from the general body skin.
(6) Two patients developed invasive lentigo maligna melanoma while on treatment.
(7) Progressive cranial nerve palsies and painful ophthalmoplegia developed in a 76-year-old man with lentigo maligna of the forehead 18 months after the excision of a spindle cell tumour of the forehead that proved on immunohistochemical study to be a malignant melanoma.
(8) In the lentigo maligna melanoma, the pigment cells clearly show dendritic processes, and emit specific green fluorescence.
(9) Evidence from several studies has established that a solitary benign lichenoid keratosis evolves from a senile lentigo.
(10) The sole new melanoma detected was an extended lentigo maligna melanoma on the right cheek, which had not been noted during a prophylactic medical examination (!)
(11) Histologic studies have shown the evolution of lentigo senilis and have established the relationship between lentigo senilis, solitary lichen planus-like keratosis, and the reticulated form of seborrheic verruca.
(12) A patient with an amelanotic lentigo malignant melanoma is presented which manifested itself initially as an erythematous flare with the subsequent development of nodules.
(14) This resulted in a total series of 37 (5.5%) lentigo maligna melanomas, 301 (45%) superficial spreading malignant melanomas, 194 (29%) nodular malignant melanomas (unchanged) and 137 (20.5%) unclassifiable malignant melanomas.
(15) After adjusting for differences in thickness and level in this study, no statistically significant differences were apparent between case survival rates for the nodular lesions and the lentigo maligna and superficial spreading melanomas.
(16) Lentigo maligna melanoma appears to have a longer duration and better prognosis than SSM or NM.
(17) The patient developed lentigo maligna on the right side of the nose.
(18) A further stadium shows pathological alterations resembling a lentigo with long rete ridges.
(19) The series included 86 lentigo maligna melanomas, 259 superficial spreading malignant melanomas, 194 nodular malignant melanomas and 130 unclassifiable malignant melanomas.
(20) The primary lesion, a lentigo maligna melanoma of the face, recurred after excision and metastasized to the parotid and upper cervical lymph nodes, and to the lungs.