(a.) Vain; ineffectual; useless; unprofitable; null; voil; nugatory; of no effect.
(v. t.) To bring to nothing; to prevent from attaining a purpose; to disappoint; to defeat; to baffle; as, to frustrate a plan, design, or attempt; to frustrate the will or purpose.
(v. t.) To make null; to nullifly; to render invalid or of no effect; as, to frustrate a conveyance or deed.
Example Sentences:
(1) Michael Schumacher’s manager hopes F1 champion ‘will be here again one day’ Read more Last year, Red Bull were frustrated by Mercedes, Ferrari and Honda as they desperately looked for a new engine supplier.
(2) He had been extremely frustrated that indicators of economic recovery over the past few days had been drowned out by the clamour over the Labour leadership.
(3) Gallic wine sales in the UK have been tumbling for the past 20 years, but the news that France, once the largest exporter to these shores, has slipped behind Australia, the United States, Italy and now South Africa will have producers gnawing their knuckles in frustration.
(4) The pattern of results is consistent with a role for the dorsal bundle in attentional processes but appears to contradict the predictions required if the dorsal bundle were to have a role in frustrative nonreward.
(5) The former Stoke City manager Pulis had reportedly been left frustrated by the club failing to push through deals for various players he targeted to strengthen the Palace squad.
(6) At the weekend the couple’s daughter, Holly Graham, 29, expressed frustration at the lack of information coming from the Foreign Office and the tour operator that her parents travelled with.
(7) Conclusion 1 says that "deliberate attempts were made to frustrate these interviews" – which appears to be an exaggeration.
(8) It is deeply moving hearing him talk now – as if from the grave – about a Christmas Day when he felt so frustrated and cut-off from his family that he had to go into the office to escape.
(9) "It's immensely frustrating and I've got to the point now where I can't do internships," he said.
(10) The announcement comes amid mounting frustration in the international community over Israel’s continued settlement activity, regarded by many countries as illegal.
(11) Hinton-Teoh says: “People are frustrated because it’s taken so long, there’s a valid frustration of the laboured nature of achieving marriage equality.
(12) In many ways, perhaps, but it also must be hugely frustrating for Arsenal’s followers that their team waited until the second leg before reminding us of their qualities.
(13) It frustrates customers, eats up their data allowance and can jeopardise their privacy.
(14) These results support Frankl's theory that sexual frustration may be a manifestation of a more general existential frustration.
(15) Manchester City frustrated by Everton and Sterling’s late penalty claim Read more More than anyone, Giroud took the game to Liverpool.
(16) His normally excellent first touch often let him down and he grew frustrated with the constant attention he received from his Colombian markers.
(17) Are we moving from a culture where MPs stayed in parliament until booted out, to one where many do five years and move on, frustrated and exhausted?
(18) Though the exercises have given the US a chance to vent its frustration at what appears to be state-sponsored espionage and theft on an industrial scale, China has been belligerent.
(19) In the not too distant past, veterinarians, frustrated by lack of technical competence, ignored the emotional needs of clients.
(20) Troh, a 54-year-old nursing assistant, issued a statement on Wednesday that said: “I trust a thorough examination will take place regarding all aspects of his care … I am now dealing with the sorrow and anger that his son was not able to see him before he died.” That appeared to be a reference to frustration at the hospital’s initial failure to diagnose him correctly, and a delay of several days before they treated him with experimental drugs.
Irritate
Definition:
(v. t.) To render null and void.
(v. t.) To increase the action or violence of; to heighten excitement in; to intensify; to stimulate.
(v. t.) To excite anger or displeasure in; to provoke; to tease; to exasperate; to annoy; to vex; as, the insolence of a tyrant irritates his subjects.
(v. t.) To produce irritation in; to stimulate; to cause to contract. See Irritation, n., 2.
(n.) To make morbidly excitable, or oversensitive; to fret; as, the skin is irritated by friction; to irritate a wound by a coarse bandage.
(a.) Excited; heightened.
Example Sentences:
(1) Postpartum management is directed toward decreasing vasospasm and central nervous system irritability and maintaining fluid and electrolyte balance.
(2) testosterone, fentanyl, nicotine) may ultimately be administered in this way, important questions pertaining to pharmacology (tolerance), toxicity (irritation, sensitisation) and dose sufficiency (penetration enhancement) remain.
(3) It was shown that the antibiotic had low acute toxicity, did not cumulate and had no skin-irritating effect.
(4) Inhibition of binding of [3H]TPA to the receptor preparation by tigliane and ingenane DTE correlates with irritant activity in vivo, while some daphnane and 1 alpha-alkyldaphnane DTE inhibit binding of [3H]TPA in a less pronounced manner but still are very irritant.
(5) Exposure to irritants was also more common among the asthmatics than the nonasthmatics with similar exposure to organic allergens (P = 0.004).
(6) The purpose of this study was to develop a new model for the induction of chronic irritant contact dermatitis, which would reflect well the conditions of daily practice.
(7) The drug I started taking caused an irritating, chronic cough, which disappeared when I switched to an inexpensive diuretic.
(8) These injections led to epidermal hyperplasia in areas overlying the irritant and the effect was most significant when the irritant was placed in the upper dermis.
(9) Two children required lidocaine therapy for cardiac irritability manifesting as multifocal PVCs and ventricular tachycardia.
(10) In autumn, leaf-heaps composted themselves on sunken patios, and were shovelled up by irritated owners of basement flats.
(11) The dietary fibre intake of 25 patients with the irritable bowel syndrome was assessed by dietary recall over one week for the period before onset of symptoms, at diagnosis and after six months treatment with bran and a fibre-rich diet, and compared with controls matched for age and sex.
(12) A case of epidermoid tumor of the sacral area with S3 root irritation resulting in bladder dysfunction is presented and its possible relationship to spinal puncture is discussed.
(13) The present study did not identify any baseline parameters such as initial prostate volume, peak flow rates, or obstructive or irritative symptom scores that correlated with clinical outcome.
(14) Scores on the "dependent smoking" subscale of the smoking motivation questionnaire correlated significantly with overall withdrawal severity, craving, and increased irritability.
(15) The airways can be affected by inflammation, can be targets of infection, and can respond to chemical irritants with bronchoconstrictive responses.
(16) Some pulp irritation can occur if deep restorations are not placed over a protective film.
(17) MIDAZOLAM IS SUPERIOR TO DIAZEPAM IN CERTAIN WAYS: it has a more rapid onset; produces greater anterograde amnesia, less postoperative drowsiness, less venous irritation and less likelihood of thrombophlebitis development.
(18) Primary invasive adenocarcinoma of the bladder was diagnosed in a fifty-two-year-old male with a two-month history of irritative voiding symptoms.
(19) We studied seventy patients, 23 males and 47 females with irritable bowel syndrome in adolescence aged 13-19 yrs, who visited the department of psychosomatic medicine in Takano Hospital during about six year period of April, 1986-July, 1992.
(20) The study suggested that 1) diabetes and "prediabetes" produce significant changes in levels of chondroitin 4, 6, and dermatan sulfates within alveolar bone, 2) in "prediabetic" animals, interdental bone loss occurs prior to the onset of clinical symptoms and in the absence of local irritating factors, the bone height appears to return to normal levels, and 3) there may be a correlation between alveolar bone height and relative levels of dermatan sulfate.