(1) FUB 1 specifically recognises both native and denatured bovine carbonic anhydrase in ELISA assays.
(2) We reported a new monoclonal antibody, designated FUB-1, reacting with normal and neoplastic large lymphoid cells.
(3) In the normal lymphoid tissue, FUB-1 reacted with large lymphoid cells, but not with small or medium-sized lymphoid cells or plasma cells.
(4) FUB-1 also reacted with normal glandular epithelium and various adenocarcinomas.
(5) Carbonic anhydrase (CA) from mouse erythrocyte membranes is recognised as an autoantigen in Western blotting experiments with FUB 1, a murine IgM monoclonal antibody that binds both phosphatidylcholine and bromelain-treated mouse red blood cells (BrMRBC).
(6) The serological identity of the determinants of CA and BrMRBC was confirmed by specific absorption of both FUB 1 and LPS-serum with BrMRBC and normal mouse erythrocytes.
(7) Systematic examination of model-dependent predictions of changes in the hepatic extraction ratio (E), following alteration in the unbound fraction of drug in plasma (fub), should allow sensitive discrimination between the venous equilibrium model (model I) and the sinusoidal perfusion model (model II) of hepatic sinusoidal function if drugs which show high clearance of free drug are used.
(8) From SDS-PAGE, and blotting experiments with whole mouse erythrocytes, we found two closely spaced glycoprotein bands in the 30 kD region that reacted with both FUB 1 and LPS-serum.
(9) Conversely, data for phenytoin (E = 0.69 at fub = 1) failed to discriminate between models, as predicted by our analysis.
(10) Specifically, data related to diazepam (E = 0.95 at fub = 1) clearly conformed to the predictions of the sinusoidal perfusion model and differed markedly from those of the venous equilibrium model.
(11) The mutations, fub-1(b45) and fub-1(b126), were independently isolated from progeny of gamma-irradiated females.
(12) In fub-1 mutants, in which myofibrils are disorganized in all skeletal muscle cells, the MP appear and elongate normally, but ordered actin filament bundles are not seen.
(13) In addition, the FUB-1 antigen was not found in resting cells in the peripheral blood (PB), but it was induced on mononuclear cells of PB by addition of PWM or PMA.
(14) FUB-1 may be useful to investigate the mechanism of in vitro blastoid transformation or activation of lymphoid cells.
(15) These findings indicate that the FUB-1 antigen appears to be expressed on normal lymphoid cells during blastoid transformation and on neoplastic large lymphoid cells.
(16) FUB-1 was produced using a Burkitt's lymphoma cell line (HBL-5) as an immunogen.
(17) Carbonic anhydrases from a range of mammalian species were found to be crossreactive with FUB 1 and LPS-serum by Western blotting, whereas human glycophorin A and human asialoglycophorin were not recognised by the antibodies.
Fud
Definition:
(n.) The tail of a hare, coney, etc.
(n.) Woolen waste, for mixing with mungo and shoddy.
Example Sentences:
(1) These findings suggest that avian skin is resistant to pressure-induced decubital ulceration and that pressure is unlikely to be either the cause of or a significant contributor to FUD.
(2) In an attempt to experimentally reproduce focal ulcerative dermatitis (FUD) in turkeys, pressures of 94, 136, and 240 mmHg were applied for 2, 4, or 6 hr daily for 4 consecutive days to unfeathered breast skin of six 9-week-old toms.
(3) We have characterized two independently isolated point mutants in Chlamydomonas reinhardtii, ac-u-a-1-15 and FUD 17, mapping to the chloroplast ac-u-a locus which corresponds to the atpE gene.