(1) FUB 1 specifically recognises both native and denatured bovine carbonic anhydrase in ELISA assays.
(2) We reported a new monoclonal antibody, designated FUB-1, reacting with normal and neoplastic large lymphoid cells.
(3) In the normal lymphoid tissue, FUB-1 reacted with large lymphoid cells, but not with small or medium-sized lymphoid cells or plasma cells.
(4) FUB-1 also reacted with normal glandular epithelium and various adenocarcinomas.
(5) Carbonic anhydrase (CA) from mouse erythrocyte membranes is recognised as an autoantigen in Western blotting experiments with FUB 1, a murine IgM monoclonal antibody that binds both phosphatidylcholine and bromelain-treated mouse red blood cells (BrMRBC).
(6) The serological identity of the determinants of CA and BrMRBC was confirmed by specific absorption of both FUB 1 and LPS-serum with BrMRBC and normal mouse erythrocytes.
(7) Systematic examination of model-dependent predictions of changes in the hepatic extraction ratio (E), following alteration in the unbound fraction of drug in plasma (fub), should allow sensitive discrimination between the venous equilibrium model (model I) and the sinusoidal perfusion model (model II) of hepatic sinusoidal function if drugs which show high clearance of free drug are used.
(8) From SDS-PAGE, and blotting experiments with whole mouse erythrocytes, we found two closely spaced glycoprotein bands in the 30 kD region that reacted with both FUB 1 and LPS-serum.
(9) Conversely, data for phenytoin (E = 0.69 at fub = 1) failed to discriminate between models, as predicted by our analysis.
(10) Specifically, data related to diazepam (E = 0.95 at fub = 1) clearly conformed to the predictions of the sinusoidal perfusion model and differed markedly from those of the venous equilibrium model.
(11) The mutations, fub-1(b45) and fub-1(b126), were independently isolated from progeny of gamma-irradiated females.
(12) In fub-1 mutants, in which myofibrils are disorganized in all skeletal muscle cells, the MP appear and elongate normally, but ordered actin filament bundles are not seen.
(13) In addition, the FUB-1 antigen was not found in resting cells in the peripheral blood (PB), but it was induced on mononuclear cells of PB by addition of PWM or PMA.
(14) FUB-1 may be useful to investigate the mechanism of in vitro blastoid transformation or activation of lymphoid cells.
(15) These findings indicate that the FUB-1 antigen appears to be expressed on normal lymphoid cells during blastoid transformation and on neoplastic large lymphoid cells.
(16) FUB-1 was produced using a Burkitt's lymphoma cell line (HBL-5) as an immunogen.
(17) Carbonic anhydrases from a range of mammalian species were found to be crossreactive with FUB 1 and LPS-serum by Western blotting, whereas human glycophorin A and human asialoglycophorin were not recognised by the antibodies.
Hub
Definition:
(n.) The central part, usually cylindrical, of a wheel; the nave. See Illust. of Axle box.
(n.) The hilt of a weapon.
(n.) A rough protuberance or projecting obstruction; as, a hub in the road. [U.S.] See Hubby.
(n.) A goal or mark at which quoits, etc., are cast.
(n.) A hardened, engraved steel punch for impressing a device upon a die, used in coining, etc.
(n.) A screw hob. See Hob, 3.
(n.) A block for scotching a wheel.
Example Sentences:
(1) Heathrow, likewise, said Gatwick's new runway would not solve the issue of hub capacity.
(2) It recognises the diverse needs of the affected populations”, said Scott DiPretoro, who works in the IFRC’s Panama hub.
(3) Both initiatives, which are still being developed, have been well-received by Jakarta governor Basuki Tjahaja Purnama, who says they could help get more people from their homes to public transport hubs and has offered technical support.
(4) Thirty (56.6%) had external origin (semiquantitative skin culture positive), 12 (22.6%) had an internal origin (semiquantitative hub culture positive), and 8 (15.1%) had both origins.
(5) Martin Frobisher, the area director for Network Rail, said: "The Northern Hub and electrification programme is the biggest investment in the railway in the north of England for a generation and will transform rail travel for millions of passengers every year."
(6) The proximal extension tubing minimizes manipulation of the hub of the needle, which may lead to dislodgement of the needle, and permits a sampling port with minimal dead space between it and the fetal circulation.
(7) Locally brokered ceasefires have taken effect elsewhere in Syria in recent months, notably in the Moadimeyah district of Damascus, which was also once a hub of opposition control.
(8) The BBC will then work with the developers Stanhope on a three-year project to turn TV Centre into a new creative hub where the corporation will retain a studio presence alongside planned residential, office and leisure premises.
(9) To check the Hub while in an app, you use your thumb to swipe the screen from left to right, and can "peek" at the Hub's inbox.
(10) But others point out that Freeh and Clinton were in well-publicised dispute for most of the president's time in office and that Miami is the main transport hub for most countries in the Caribbean, and so the most obvious venue for the interviews.
(11) The King's Fund's Time to Think Differently campaign highlighted the importance of the home – not the hospital or care home – as the primary hub of care.
(12) Kristen Woolf, girl-centred practice and strategy director, The Girl Hub , London, UK, @girleffect Don't lose focus on girls: Very clearly men and boys have got to be a central component of the solution, but we need to tread carefully here not to lose the focus on equality and empowerment for girls and women.
(13) Migration has turned a sleepy town with a population of 31,000 in 1872 into today's megacity of 21 million, the ninth-biggest city in the world and South America's wealthiest and most important economic hub.
(14) As Cook put it: “From our point of view, the time for inaction has passed.” The values-led business hub is funded by SC Johnson.
(15) Already, the growing hub is surrounded by five-star hotels and hundreds of luxury villa and apartments.
(16) In this life,” he said, smiling, “you have to make some money.” He then spelled out the cartel’s proposition: it would pay Sirleaf handsomely in exchange for his help in using Liberia as a transit hub for smuggling cocaine from Colombia into Europe.
(17) Photograph: Rozena Crossman Despite its small size, the café has a lighter and more modern atmosphere than the cramped bookshop next door, a famous hub for influential writers.
(18) As Chambers's lawyers pointed out, he was not attempting to close down a public transport hub but urging it to resume normal working operations.
(19) Ofcom has already moved to allow more regional hubs for local commercial radio, relax local programming quotas, and encourage digital stations.
(20) "And with the help of the council we're looking to increase the number of hubs and bikes so we've got most of the city covered.