(1) FUB 1 specifically recognises both native and denatured bovine carbonic anhydrase in ELISA assays.
(2) We reported a new monoclonal antibody, designated FUB-1, reacting with normal and neoplastic large lymphoid cells.
(3) In the normal lymphoid tissue, FUB-1 reacted with large lymphoid cells, but not with small or medium-sized lymphoid cells or plasma cells.
(4) FUB-1 also reacted with normal glandular epithelium and various adenocarcinomas.
(5) Carbonic anhydrase (CA) from mouse erythrocyte membranes is recognised as an autoantigen in Western blotting experiments with FUB 1, a murine IgM monoclonal antibody that binds both phosphatidylcholine and bromelain-treated mouse red blood cells (BrMRBC).
(6) The serological identity of the determinants of CA and BrMRBC was confirmed by specific absorption of both FUB 1 and LPS-serum with BrMRBC and normal mouse erythrocytes.
(7) Systematic examination of model-dependent predictions of changes in the hepatic extraction ratio (E), following alteration in the unbound fraction of drug in plasma (fub), should allow sensitive discrimination between the venous equilibrium model (model I) and the sinusoidal perfusion model (model II) of hepatic sinusoidal function if drugs which show high clearance of free drug are used.
(8) From SDS-PAGE, and blotting experiments with whole mouse erythrocytes, we found two closely spaced glycoprotein bands in the 30 kD region that reacted with both FUB 1 and LPS-serum.
(9) Conversely, data for phenytoin (E = 0.69 at fub = 1) failed to discriminate between models, as predicted by our analysis.
(10) Specifically, data related to diazepam (E = 0.95 at fub = 1) clearly conformed to the predictions of the sinusoidal perfusion model and differed markedly from those of the venous equilibrium model.
(11) The mutations, fub-1(b45) and fub-1(b126), were independently isolated from progeny of gamma-irradiated females.
(12) In fub-1 mutants, in which myofibrils are disorganized in all skeletal muscle cells, the MP appear and elongate normally, but ordered actin filament bundles are not seen.
(13) In addition, the FUB-1 antigen was not found in resting cells in the peripheral blood (PB), but it was induced on mononuclear cells of PB by addition of PWM or PMA.
(14) FUB-1 may be useful to investigate the mechanism of in vitro blastoid transformation or activation of lymphoid cells.
(15) These findings indicate that the FUB-1 antigen appears to be expressed on normal lymphoid cells during blastoid transformation and on neoplastic large lymphoid cells.
(16) FUB-1 was produced using a Burkitt's lymphoma cell line (HBL-5) as an immunogen.
(17) Carbonic anhydrases from a range of mammalian species were found to be crossreactive with FUB 1 and LPS-serum by Western blotting, whereas human glycophorin A and human asialoglycophorin were not recognised by the antibodies.
Nub
Definition:
(v. t.) To push; to nudge; also, to beckon.
(n.) A jag, or snag; a knob; a protuberance; also, the point or gist, as of a story.
Example Sentences:
(1) Out of the latter, NUB congenital defect was in 4, total epispadia in 1, spina bifida in 1 patient.
(2) In the case of S. enteritidis NUB 31, the effect of CPS-K was detectable only when more than 20 mug per mouse was injected.
(3) And that is the nub of the FT report: grim reading for chancellor George Osborne as he puts the finishing touches to his 19 March budget.
(4) The peak CPS-K effect on infection with S. enteritidis NUB 1 was seen when given immediately before bacterial challenge.
(5) Some wore "slave bracelets" made out of boot laces and walked with "Black Power canes", sticks with the nub carved into a clenched fist.
(6) This is the nub of the issue and the foreign secretary's statement seems to mask a much more complex picture.
(7) Four new nuB mutations in the DNA gyrase-binding site between the G and I genes were also sequenced and found to be identical to the nuB103 mutation sequenced previously.
(8) The nub of Zittrain’s concern is that the practice of shaping what stays and what goes from the database is hopelessly individualistic.
(9) The promotion of infection with S. enteritidis NUB 1 by CPS-K depended upon its dose, the effect of CPS-K being demonstrable up to as little as 0.2 mug per mouse.
(10) This is the nub of what I am going to call, because I've always secretly wanted to be a mathematician, the "Birmingham Liberty Paradox".
(11) And I'm hopeful that we're getting closer to the nub of the problem.
(12) The nub of the controversy was his comment that "we wouldn't have had all these problems over all these years" if Mr Thurmond, who ran a campaign to keep blacks out of white schools and neighbourhoods, had won the presidency in 1948.
(13) Both have seen very bleak scenarios depicted by either side in attempts to scare the electorate, for example with the idea that a yes vote will usher in a very authoritarian regime.” In his presentations, Baldini, who will vote yes, tries to go to what he sees as the nub of the issue.
(14) Our failing economy needs stimulating and your nub of grey meat and Mars egg are simply not sufficient.
(15) Why does it matter whether other people believe it or not?” I suspect that gets to the nub of it.
(16) As a result of enumeration of bacterial populations in the peritoneal washing, blood, liver and spleen, it was revealed that CPS-K promoted in vivo growth of S. enteritidis NUB 1 and NUB 31.
(17) The NUB-6 cell line consisted of two distinct cell subtypes, small typical neuroblasts and larger spheroid-forming cells, while NUB-7 was homogeneously neuroblastic.
(18) All the children were operated on: NUB reconstruction according to Davis, bilateral uretero-cystostomy according to Coen.
(19) Two new neuroblastoma (NB) cell lines, NUB-6 and NUB-7, were established from recurrent and primary NB tumours respectively and identified conclusively as NB by their phenotypic characteristics, catecholamine production and N-myc amplification.
(20) Urodynamic studies showed the absence of detrusor-sphincter dyssynergia and confirmed organic nature of NUB lesion.