(v. t.) To liquefy by heat; to render fiuid; to dissolve; to melt.
(v. t.) To unite or blend, as if melted together.
(v. i.) To be reduced from a solid to a Quid state by heat; to be melted; to melt.
(v. i.) To be blended, as if melted together.
(n.) A tube or casing filled with combustible matter, by means of which a charge of powder is ignited, as in blasting; -- called also fuzee. See Fuze.
Example Sentences:
(1) Synthetic DNA corresponding to the hydrophobic domain of cytochrome b5 was enzymatically fused in-frame to cloned DNA corresponding to the C-terminus of the Escherichia coli enzyme, beta-galactosidase.
(2) The latter findings reinforce the concept that in pathologic states associated with cerebral oedema, pinocytotic vesicles fuse to form transendothelial channels which transport plasma proteins into brain.
(3) DNA fragments coding for signal peptides with different lengths (28, 31, 33 and 41 amino acids from the translation initiator Met) were prepared and fused with the E. coli beta-lactamase structural gene.
(4) When these sequences were fused to the N terminus of yeast cytochrome oxidase subunit IV lacking its own presequence, they directed the attached subunit IV to its correct intramitochondrial location in vivo.
(5) In addition, 15 double mutant xylS genes were constructed in vitro by fusing parts of various mutant genes to produce mutant regulators exhibiting C-terminal and N-terminal amino acid substitutions.
(6) Descending neurons have opposite structural polarity, arising in the brain and terminating in segmental regions of the fused ventral ganglia.
(7) Some of them situated in a particular environment fused with the tail sequence to produce monomeric ubiquitin genes that were maintained across species.
(8) Fusing equimolecular amounts of 3-oxaspiro[5.5]undecane-2.4-dione with certain amino compounds afforded the corresponding N-substituted azaspirodiones.
(9) Theoretical analyses of parameters for submicron fluorescence recovery after photobleaching measurements in intact mitoplasts support the finding of highly mobile redox components diffusing at the same rates as determined in conventional fluorescence recovery after photobleaching measurements in fused, ultralarge inner membranes.
(10) A simple method has been developed for fusing synaptic vesicles into spherical structures 20-50 micron in diameter.
(11) The results obtained allow to conclude that heterophasic condition of the fused cells is one of the causes of pathological mitosis of polykaryons and of their death.
(12) At high protein concentrations, three footprints fuse to a 106-bp protected region, suggesting that this segment specifically binds several proteins of lower affinity or abundance.
(13) Traction spurs with segmental hypermobility were found more commonly at the L4-5 level in patients whose spines were not fused, particularly women.
(14) As for possible causes of reduced Leydig cell activity it was investigated whether the testis was (1) hypoplastic; (2) abnormally fused with the epididymis; (3) located in the abdomen; (4) or UT was associated with hypospadias.
(15) We report a case of seminoma associated with crossed fused renal ectopia and a duplicated vena cava.
(16) Large intracellular vacuoles, which arose from dilated cisternae of the rough-surfaced endoplasmic reticulum, were fused together, and marked swelling of the mitochondria was also noted.
(17) Apparently the myoblasts have become postmitotic and competent to fuse into muscle fibers during their initial exposure to fusion inducing medium, even though cytodifferentiation has been blocked.
(18) Our results clearly demonstrate that capillary GC analysis of amino acids using fused silica bonded-phase columns provides data with good precision and in general excellent agreement with ion-exchange analyses.
(19) We have perturbed the dynamics of the nuclear lamins by means of cell fusion between mitotic and interphase cells and have studied redistribution of lamins in fused cells as a function of extracellular pH levels.
(20) To identify regulatory elements of these promoters, we fused CSF-1R genomic sequences to bacterial reporter genes and introduced the resulting constructs into human cell lines and mouse fibroblasts.
Scaffold
Definition:
(n.) A temporary structure of timber, boards, etc., for various purposes, as for supporting workmen and materials in building, for exhibiting a spectacle upon, for holding the spectators at a show, etc.
(n.) Specifically, a stage or elevated platform for the execution of a criminal; as, to die on the scaffold.
(n.) An accumulation of adherent, partly fused material forming a shelf, or dome-shaped obstruction, above the tuyeres in a blast furnace.
(v. t.) To furnish or uphold with a scaffold.
Example Sentences:
(1) Detailed analysis presented here reveals the presence of only two closely linked sites in 35,000 base-pairs scanned that mediate attachment of the dhfr gene to the nuclear scaffold.
(2) Both contain an internal protein (VP22a in the case of HSV-1 B capsids and gp8 or "scaffolding" protein in phage P22) that can be extracted in vitro with GuHCl and that is absent from mature virions.
(3) These muscle cells are then cultured on a scaffold with nutrients and essential vitamins and grown to desired quantities.
(4) According to the Times of India newspaper, officials handling the royal tour requested scaffolding at the site be taken down.
(5) The arrival of sensory axons in the brain triggers changes in glial shape and position that lead to the formation of a glial scaffolding for the developing glomeruli.
(6) After more than a quarter of a century of camping out, the house, with its seven flights of stairs (a trial to Lessing in her final years), seemed almost to be supported by a precarious interior scaffolding of piles of books and shelves.
(7) Two recently identified genes (genes 67 and 68) and one already known gene (gene 22), whose products are scaffold constituents, have been investigated.
(8) In the preceding article we described a polyclonal antibody that recognizes cSc-1, a major polypeptide component of the chicken mitotic chromosome scaffold.
(9) A less complex pattern was found for nuclear scaffolds.
(10) The products of three of these genes, the portal, scaffolding, and coat proteins, are structural components of the precursor particle, and two, the products of genes 2 and 3, are not.
(11) We now demonstrate that the protein scaffold may be isolated independently of the DNA by treating HeLa chromosomes with micrococcal nuclease before removing the histones.The chromosomal scaffolds may be isolated by sucrose density gradient centrifugation as a well-defined peak that is stable in 2 M sodium chloride, but is dissociated by treatment with proteases, 4 M urea, or 0.1% sodium dodecyl sulfate.
(12) We speculate that the microfibril bundles serve as a scaffolding for the corneal stroma or as a light-diffracting element.
(13) Thus, they represent a strong candidate as a scaffold ligament or tendon prosthesis if crosslink density can be increased.
(14) In osteoconduction, the implant does not provide many viable cells but rather acts as a scaffolding for the ingrowth of new bone from the margins of the defect with the concurrent resorption of the implant; cortical bone grafts or banked bone segments are examples of this "creeping substitution."
(15) In the control grafts regenerating axons grew almost completely through the inside of the basal lamina scaffolds (92%) and adhered to the structure, while in the anti-laminin antiserum treated grafts the axons were present outside (52%) and inside (48%) the scaffolds simultaneously.
(16) These preparations and sections revealed that titin, a putative scaffolding protein of sarcomeres, is present in a punctate state and also in a diffuse form throughout the cytoplasm of cardiac myocytes in the premyofibril stages (4-7 somite stages) as well as in the early stages of myofibril formation.
(17) Their massed voices roll like thunder across the open-sided, scaffold-roofed stadium.
(18) The scaffold-like structures were not accessible to G-, R-, or C-banding techniques.
(19) We conclude that synchronous assembly of the scaffold and shell is not obligatory and that naked cores can serve as intermediates in the T4 assembly pathway.
(20) The key components of the model consisted of an oligomeric lysine scaffolding to amplify peptide antigens covalently 4-fold and a lipophilic membrane-anchoring group to further amplify noncovalently the antigens many-fold in liposomal or micellar form.