(n.) A pointed or wedge-shaped instrument of metal, as a steel wedge used in mining, etc.
(n.) A sharp-pointed rod; a goad.
(n.) A spike on a gauntlet; a gadling.
(n.) A wedge-shaped billet of iron or steel.
(n.) A rod or stick, as a fishing rod, a measuring rod, or a rod used to drive cattle with.
(n.) To walk about; to rove or go about, without purpose; hence, to run wild; to be uncontrolled.
Example Sentences:
(1) N-Acetyl-beta-D-glucosaminidase (GAD) activities did not change significantly duringlate fetal, neonatal or young adult stages but increased significantly with advancing age.
(2) A more specific differentiation, as indicated by the sharp increase in GAD levels which was concurrent with an increase in interneuronal contacts, lagged behind the initial growth.
(3) GAD activity appeared in mutant spores after germination and increased to levels comparable to parent spores after 9 min of germination.
(4) In situ hybridization in normal visual cortex revealed a complex sublaminar organization of GAD-expressing cells within layers IVC and VI and a distribution of CaM II kinase alpha-expressing cells that was greatest in layers II, III, IVB, and VI.
(5) Neurogenesis of GABAergic neurons in the rat area dentata was studied combining [3H]thymidine autoradiography with immunostaining for glutamate decarboxylase (GAD), the gamma-aminobutyric acid (GABA) synthesizing enzyme.
(6) The presence of glutamic acid decarboxylase (GAD) and gamma-aminobutyric acid (GABA) was investigated in neuroretina sections from hatching quail embryos by immunocytochemistry.
(7) The hippocampal cell counts showed an increase in GAD-immunoreactive somata visualized on the fourth postischemic day.
(8) The postnatal maturation of the GABAergic innervation of the rat inferior olive was studied with an antiserum to glutamic acid decarboxylase (GAD), the GABA-synthesizing enzyme.
(9) In contrast, only modest alterations in GABA-immunoreactivity and glutamic acid decarboxylase (GAD) activity were observed in the same region.
(10) Approximately 25% of the neurons in the IC in SD rat are GAD-positive, while about 35% of the neurons in the GEPR are GAD-positive.
(11) The oxidation reaction ends in a mixture composed largely of oxidized GAD species.
(12) Although their numbers are greatest in the polymorph region of the fascia dentata (FD) and in the principal cell layers stratum pyramidale (SP) and stratum granulosum (SG), GAD immunoreactive (GAD-IR) cells are numerous in other strata that contain mostly dendrites and scattered cells.
(13) The methods and chemicals utilized were the same as those used and reported by Gad et al.
(14) However, the administration of thyroxine markedly increased CNPase activity in normal rats, whereas in hypothyroid rats the effect on both CNPase and GAD was also significant.
(15) No change in parameters of GABAergic activity, namely the glutamic acid decarboxylase (GAD) activity and high affinity GABA uptake, were observed in any of the structures examined.
(16) None of the drug treatments altered nigral GAD activity when examined after 1, 3, 6, 9 or 12 months administration.
(17) Addition of alkali to the culture media results in decrease of cell GAD activity, whereas increase of enzyme level occurs only in cells growing in unbuffered media.
(18) Vibratome sections of rat substantia nigra (SN) topically injected with colchicine were processed for glutamate decarboxylase (GAD) immunocytochemistry to reveal GABAergic neurons using electronmicroscopic procedures.
(19) GAD and ChAT omnipresence may indicate constant GABAergic HCII and its cholinergic efferent synapses, their raised content, appearance of GABA-containing HCI and related cholinergic boutons in higher vertebrates.
(20) Interestingly, the beta-galactosidase-GAD fusion protein encoded by lambda GAD is enzymatically active, catalyzing the conversion of glutamate to CO2 and GABA.
Gadabout
Definition:
(n.) A gadder
Example Sentences:
(1) Priapic gadabouts in peephole codpieces hey-nonny-no-ing past plates of glazed pig as smouldering flibbertigibbets pout and motion to their jugs.
(2) "I’d just like to subtly point out that, were this World Cup to be decided on style as opposed to football, Argentina would have crashed out in the group stages and today would mark the end of the road for Switzerland,” clangs our erstwhile minute-by-minute pal turned Mr Porter gadabout.