(n.) A pointed or wedge-shaped instrument of metal, as a steel wedge used in mining, etc.
(n.) A sharp-pointed rod; a goad.
(n.) A spike on a gauntlet; a gadling.
(n.) A wedge-shaped billet of iron or steel.
(n.) A rod or stick, as a fishing rod, a measuring rod, or a rod used to drive cattle with.
(n.) To walk about; to rove or go about, without purpose; hence, to run wild; to be uncontrolled.
Example Sentences:
(1) N-Acetyl-beta-D-glucosaminidase (GAD) activities did not change significantly duringlate fetal, neonatal or young adult stages but increased significantly with advancing age.
(2) A more specific differentiation, as indicated by the sharp increase in GAD levels which was concurrent with an increase in interneuronal contacts, lagged behind the initial growth.
(3) GAD activity appeared in mutant spores after germination and increased to levels comparable to parent spores after 9 min of germination.
(4) In situ hybridization in normal visual cortex revealed a complex sublaminar organization of GAD-expressing cells within layers IVC and VI and a distribution of CaM II kinase alpha-expressing cells that was greatest in layers II, III, IVB, and VI.
(5) Neurogenesis of GABAergic neurons in the rat area dentata was studied combining [3H]thymidine autoradiography with immunostaining for glutamate decarboxylase (GAD), the gamma-aminobutyric acid (GABA) synthesizing enzyme.
(6) The presence of glutamic acid decarboxylase (GAD) and gamma-aminobutyric acid (GABA) was investigated in neuroretina sections from hatching quail embryos by immunocytochemistry.
(7) The hippocampal cell counts showed an increase in GAD-immunoreactive somata visualized on the fourth postischemic day.
(8) The postnatal maturation of the GABAergic innervation of the rat inferior olive was studied with an antiserum to glutamic acid decarboxylase (GAD), the GABA-synthesizing enzyme.
(9) In contrast, only modest alterations in GABA-immunoreactivity and glutamic acid decarboxylase (GAD) activity were observed in the same region.
(10) Approximately 25% of the neurons in the IC in SD rat are GAD-positive, while about 35% of the neurons in the GEPR are GAD-positive.
(11) The oxidation reaction ends in a mixture composed largely of oxidized GAD species.
(12) Although their numbers are greatest in the polymorph region of the fascia dentata (FD) and in the principal cell layers stratum pyramidale (SP) and stratum granulosum (SG), GAD immunoreactive (GAD-IR) cells are numerous in other strata that contain mostly dendrites and scattered cells.
(13) The methods and chemicals utilized were the same as those used and reported by Gad et al.
(14) However, the administration of thyroxine markedly increased CNPase activity in normal rats, whereas in hypothyroid rats the effect on both CNPase and GAD was also significant.
(15) No change in parameters of GABAergic activity, namely the glutamic acid decarboxylase (GAD) activity and high affinity GABA uptake, were observed in any of the structures examined.
(16) None of the drug treatments altered nigral GAD activity when examined after 1, 3, 6, 9 or 12 months administration.
(17) Addition of alkali to the culture media results in decrease of cell GAD activity, whereas increase of enzyme level occurs only in cells growing in unbuffered media.
(18) Vibratome sections of rat substantia nigra (SN) topically injected with colchicine were processed for glutamate decarboxylase (GAD) immunocytochemistry to reveal GABAergic neurons using electronmicroscopic procedures.
(19) GAD and ChAT omnipresence may indicate constant GABAergic HCII and its cholinergic efferent synapses, their raised content, appearance of GABA-containing HCI and related cholinergic boutons in higher vertebrates.
(20) Interestingly, the beta-galactosidase-GAD fusion protein encoded by lambda GAD is enzymatically active, catalyzing the conversion of glutamate to CO2 and GABA.
Goad
Definition:
(v. t.) A pointed instrument used to urge on a beast; hence, any necessity that urges or stimulates.
(v. t.) To prick; to drive with a goad; hence, to urge forward, or to rouse by anything pungent, severe, irritating, or inflaming; to stimulate.
Example Sentences:
(1) They have informed, advocated and sometimes goaded participants in a way that will be entirely familiar to people in Europe.
(2) Thereby, it serves as a goad to thinking about conflicts between pregnant women and their fetuses in a way that emphasizes relationships rather than rights.
(3) The three young men were trying to get to grips with a troubling scene in which they lark about with a baby in its pram, poking it, pulling off its nappy, goading each other until they stone it to death.
(4) Francesco Totti has escaped with a spell on the naughty step for goading Lazio fans in the wake of Sunday's Rome derby, but has been fined €10,000 for each thumb he pointed down in a bid to rile them up.
(5) The public conscience has been stirred and professional groups--doctors, lawyers, legislators and law enforcement agencies--goaded on many occasions by feminist groups, have deliberated the various aspects of this problem.
(6) Where Google News has a sentence that tells you what the story is, Goad notes: "Facebook often has the first paragraph, so they're stealing – if you want to use that word – more of the content."
(7) I can’t tell if he’s goading him, or wanting him to join in, or do something differently.
(8) We had two young daughters who would goad him into conversation, as children will.
(9) He used a number of accounts to goad his victims when they attempted to block his comments, saying police "would do nothing" about his tirade of abuse.
(10) Goaded, taunted and tormented by the prosecution, Pistorius was perhaps his own worst enemy during cross-examination, suffering surprising memory lapses and appearing evasive, agitated, petulant and self-contradictory.
(11) Baillie, Scottish Labour’s effective interim leader at Holyrood while the party votes on a successor to replace Johann Lamont, had goaded Salmond.
(12) To a packed Bundestag, Merkel said it was "absurd" to claim Germany was trying to "dominate" Europe – an accusation which has become ever more widespread after one of her MPs made goading comments that "Europe was now speaking German" .
(13) Locals say the gangs were goaded into the violence by others from their factions elsewhere in Rio.
(14) We have a president-elect who penned in journalists at his rallies, has continued to goad the press even after his election win, and who has history of threats against journalists.
(15) He heard the boos and the goading battle cries: "No Surrender to the IRA", "Judas!
(16) But our state must resist the temptation to be goaded into tackling complicated issues with simplistic, divisive laws.
(17) "Twitter is no longer purely in the domain of early adopters; rather it is becoming a universal tool which is being used increasingly by all types of internet users, regardless of their online preferences," Goad noted.
(18) "A typical website in the UK receives around two in every five visits from search engines and obviously, the vast majority of those come via Google," according to Robin Goad, research director at Hitwise UK.
(19) Not like at the Spectator garden party, where one eyewitness described the two cabinet ministers goading each other “like a pair of rutting stags locking antlers”.
(20) He has only ever talked about his experiences once and was angry with Frischmann for revealing this in a moment of weakness as she was being goaded about her 'privileged' upbringing.