(n.) A pointed or wedge-shaped instrument of metal, as a steel wedge used in mining, etc.
(n.) A sharp-pointed rod; a goad.
(n.) A spike on a gauntlet; a gadling.
(n.) A wedge-shaped billet of iron or steel.
(n.) A rod or stick, as a fishing rod, a measuring rod, or a rod used to drive cattle with.
(n.) To walk about; to rove or go about, without purpose; hence, to run wild; to be uncontrolled.
Example Sentences:
(1) N-Acetyl-beta-D-glucosaminidase (GAD) activities did not change significantly duringlate fetal, neonatal or young adult stages but increased significantly with advancing age.
(2) A more specific differentiation, as indicated by the sharp increase in GAD levels which was concurrent with an increase in interneuronal contacts, lagged behind the initial growth.
(3) GAD activity appeared in mutant spores after germination and increased to levels comparable to parent spores after 9 min of germination.
(4) In situ hybridization in normal visual cortex revealed a complex sublaminar organization of GAD-expressing cells within layers IVC and VI and a distribution of CaM II kinase alpha-expressing cells that was greatest in layers II, III, IVB, and VI.
(5) Neurogenesis of GABAergic neurons in the rat area dentata was studied combining [3H]thymidine autoradiography with immunostaining for glutamate decarboxylase (GAD), the gamma-aminobutyric acid (GABA) synthesizing enzyme.
(6) The presence of glutamic acid decarboxylase (GAD) and gamma-aminobutyric acid (GABA) was investigated in neuroretina sections from hatching quail embryos by immunocytochemistry.
(7) The hippocampal cell counts showed an increase in GAD-immunoreactive somata visualized on the fourth postischemic day.
(8) The postnatal maturation of the GABAergic innervation of the rat inferior olive was studied with an antiserum to glutamic acid decarboxylase (GAD), the GABA-synthesizing enzyme.
(9) In contrast, only modest alterations in GABA-immunoreactivity and glutamic acid decarboxylase (GAD) activity were observed in the same region.
(10) Approximately 25% of the neurons in the IC in SD rat are GAD-positive, while about 35% of the neurons in the GEPR are GAD-positive.
(11) The oxidation reaction ends in a mixture composed largely of oxidized GAD species.
(12) Although their numbers are greatest in the polymorph region of the fascia dentata (FD) and in the principal cell layers stratum pyramidale (SP) and stratum granulosum (SG), GAD immunoreactive (GAD-IR) cells are numerous in other strata that contain mostly dendrites and scattered cells.
(13) The methods and chemicals utilized were the same as those used and reported by Gad et al.
(14) However, the administration of thyroxine markedly increased CNPase activity in normal rats, whereas in hypothyroid rats the effect on both CNPase and GAD was also significant.
(15) No change in parameters of GABAergic activity, namely the glutamic acid decarboxylase (GAD) activity and high affinity GABA uptake, were observed in any of the structures examined.
(16) None of the drug treatments altered nigral GAD activity when examined after 1, 3, 6, 9 or 12 months administration.
(17) Addition of alkali to the culture media results in decrease of cell GAD activity, whereas increase of enzyme level occurs only in cells growing in unbuffered media.
(18) Vibratome sections of rat substantia nigra (SN) topically injected with colchicine were processed for glutamate decarboxylase (GAD) immunocytochemistry to reveal GABAergic neurons using electronmicroscopic procedures.
(19) GAD and ChAT omnipresence may indicate constant GABAergic HCII and its cholinergic efferent synapses, their raised content, appearance of GABA-containing HCI and related cholinergic boutons in higher vertebrates.
(20) Interestingly, the beta-galactosidase-GAD fusion protein encoded by lambda GAD is enzymatically active, catalyzing the conversion of glutamate to CO2 and GABA.
Rad
Definition:
() imp. & p. p. of Read, Rede.
Example Sentences:
(1) The axons of A5, RPoOl and RaD neurons exhibit no lateral predominance in their spinal projections.
(2) This was treated with local radiation therapy consisting of 2700 rads administered in 15 fractions during a period of 28 days.
(3) Genetical analysis revealed that resistance to trimethoprim resulted from forward mutations at separate loci rather than back mutations of rad 6 or rad 18 alleles.
(4) Analysis was performed on all patients who received any amount of therapy (VSG) and on the Adequately Treated Group (ATG), who had received 5000 or more rads radiotherapy, two or more courses of chemotherapy, and had a minimum survival of 8 or more weeks (the interval that would have been required to have received either the radiotherapy or chemotherapy).
(5) Liability of retransplanted syngeneic skin grafts to rejection could be almost entirely abolished by their exposure to 300 rads irradiation before placement on the intermediate host.
(6) Fourteen patients entered the study and each received megavoltage therapy to give a mean dose of 4600 rad to the pituitary over 31 days.
(7) At the 200 rad level, the mouse with normal karyotype was compared with the T(1;13)70H translocation heterozygote and the Ts(1(13))7OH tertiary trisomic of normal appearance.
(8) Of these, the first 36 patients received single doses to the UHB, mid-body (MB), or LHB using doses of 600 rad to the UHB and 800 rad to MB and LHB.
(9) This treatment will be repeated until a total dose of 5000--6000 rad.
(10) The morphologic changes produced in the liver through irradiation at the rate of 1000 rad are characterized chiefly by a well expressed fatty dystrophia.
(11) The hypoxic fraction increased dramatically when these tumours invaded the subcutaneous tissues, or when tumours were implanted subcutaneously (TCD50 greater than 5,544 rad).
(12) In the membranes a phosphoprotein of 32 kDa belonging to the NADPH oxidase-cytochrome b-245 system (P. Bellavite et al., Free Rad.
(13) The radiation dose to the kidney (3.6 rad) and to the whole body (0.36 rad) was acceptable.
(14) The generation of cellular and supernatant IL 2R was: dependent on cellular activation, rapid, radioresistant (3000 rad), and inhibited by cycloheximide treatment.
(15) He was submitted to radiotherapy with linear acceleration (total dose of 4000 rads) and surgery, during which the tumor could not be completely removed due to its large size.
(16) Of mice treated with 500 rad, 44% were cured, as were 100% given 800 rad of treatment.
(17) External beam radiation was also given (6000 rads) to 16 patients for curative intent and (3000 rads) to 9 patients for palliative intent.
(18) In order to evaluate the usefulness of gamma-ray-irradiation to improve the tolerance to wear of the sockets, the worn surface of the 2.5 M rad gamma-ray-irradiated HDP sockets after total hip arthroplasty has been quantified by a newly-developed 3 dimensional (3-D) image analysis method in combination with scanning electron microscopy (SEM).
(19) 100 to 1600 rad doses did not produce adverse effects on these cells.
(20) Chromosome aberrations induced by 500 rads gamma ray irradiation (dicentrics, rings, and fragments) were observed at the ultrastructural level using the "whole mount" technique.