(1) N-Acetyl-beta-D-glucosaminidase (GAD) activities did not change significantly duringlate fetal, neonatal or young adult stages but increased significantly with advancing age.
(2) A more specific differentiation, as indicated by the sharp increase in GAD levels which was concurrent with an increase in interneuronal contacts, lagged behind the initial growth.
(3) GAD activity appeared in mutant spores after germination and increased to levels comparable to parent spores after 9 min of germination.
(4) In situ hybridization in normal visual cortex revealed a complex sublaminar organization of GAD-expressing cells within layers IVC and VI and a distribution of CaM II kinase alpha-expressing cells that was greatest in layers II, III, IVB, and VI.
(5) Neurogenesis of GABAergic neurons in the rat area dentata was studied combining [3H]thymidine autoradiography with immunostaining for glutamate decarboxylase (GAD), the gamma-aminobutyric acid (GABA) synthesizing enzyme.
(6) The presence of glutamic acid decarboxylase (GAD) and gamma-aminobutyric acid (GABA) was investigated in neuroretina sections from hatching quail embryos by immunocytochemistry.
(7) The hippocampal cell counts showed an increase in GAD-immunoreactive somata visualized on the fourth postischemic day.
(8) The postnatal maturation of the GABAergic innervation of the rat inferior olive was studied with an antiserum to glutamic acid decarboxylase (GAD), the GABA-synthesizing enzyme.
(9) In contrast, only modest alterations in GABA-immunoreactivity and glutamic acid decarboxylase (GAD) activity were observed in the same region.
(10) Approximately 25% of the neurons in the IC in SD rat are GAD-positive, while about 35% of the neurons in the GEPR are GAD-positive.
(11) The oxidation reaction ends in a mixture composed largely of oxidized GAD species.
(12) Although their numbers are greatest in the polymorph region of the fascia dentata (FD) and in the principal cell layers stratum pyramidale (SP) and stratum granulosum (SG), GAD immunoreactive (GAD-IR) cells are numerous in other strata that contain mostly dendrites and scattered cells.
(13) The methods and chemicals utilized were the same as those used and reported by Gad et al.
(14) However, the administration of thyroxine markedly increased CNPase activity in normal rats, whereas in hypothyroid rats the effect on both CNPase and GAD was also significant.
(15) No change in parameters of GABAergic activity, namely the glutamic acid decarboxylase (GAD) activity and high affinity GABA uptake, were observed in any of the structures examined.
(16) None of the drug treatments altered nigral GAD activity when examined after 1, 3, 6, 9 or 12 months administration.
(17) Addition of alkali to the culture media results in decrease of cell GAD activity, whereas increase of enzyme level occurs only in cells growing in unbuffered media.
(18) Vibratome sections of rat substantia nigra (SN) topically injected with colchicine were processed for glutamate decarboxylase (GAD) immunocytochemistry to reveal GABAergic neurons using electronmicroscopic procedures.
(19) GAD and ChAT omnipresence may indicate constant GABAergic HCII and its cholinergic efferent synapses, their raised content, appearance of GABA-containing HCI and related cholinergic boutons in higher vertebrates.
(20) Interestingly, the beta-galactosidase-GAD fusion protein encoded by lambda GAD is enzymatically active, catalyzing the conversion of glutamate to CO2 and GABA.
Idle
Definition:
(superl.) Of no account; useless; vain; trifling; unprofitable; thoughtless; silly; barren.
(superl.) Not called into active service; not turned to appropriate use; unemployed; as, idle hours.
(superl.) Not employed; unoccupied with business; inactive; doing nothing; as, idle workmen.
(superl.) Given rest and ease; averse to labor or employment; lazy; slothful; as, an idle fellow.
(superl.) Light-headed; foolish.
(v. i.) To lose or spend time in inaction, or without being employed in business.
(v. t.) To spend in idleness; to waste; to consume; -- often followed by away; as, to idle away an hour a day.
Example Sentences:
(1) Even with hepatic lipase, phospholipid hydrolysis could not deplete VLDL and IDL of sufficient phospholipid molecules to account for the loss of surface phospholipid that accompanies triacylglycerol hydrolysis and decreasing core volume as LDL is formed (or for conversion of HDL2 to HDL3).
(2) Eager to show I was a good student, the next time we had sex, I noticed that one of my hands was, indeed, lying idle – and started to pat him on the back, absently, as if trying to wind a baby.
(3) And imagine he then found that, far from acting swiftly to capture, arrest and charge him, the Metropolitan police force (who knew something about his activities) initially stood idly by as his list of victims grew and grew.
(4) The balance is fragile and the threat of a spiral of decline is not an idle one.
(5) The KBS hypothesis of autism is not simply an idle exercise.
(6) "There are idle MPs with no outside interests and there are fantastic public servants that do have them."
(7) On Saturday an idle digg ing machine signalled the hasty clearing of the building site to make way for the refugees, who have fled from countries including Syria and Eritrea .
(8) In circumstances in which energy conversion rate and supplies of reducing power exceed the capacity of the biosynthetic machinery, energy-dependent H2 production presumably represents a regulatory device that facilitates "energy-idling."
(9) Relative to EM, Meritec had the highest specificity (97%), followed by Virogen (95%), IDL (91%), Pathfinder (85%), Behring (81%), Bartels (72%), and Rotazyme (71%).
(10) Thus, introducing fish oil into an atherogenic diet reduced the number of VLDL, IDL and LDL particles in plasma by as much as 50%, reduced the cholesteryl ester content of the circulating lipoprotein, and reduced the ability of the VLDL to stimulate cholesterol esterification in macrophages.
(11) 12.44am BST Ah, here's @NotCoachTito, sitting somewhere idly wondering what it's like in Fenway tonight...actually, he may have a decent idea of the atmosphere.
(12) It was on the set of The Frost Report that production staff began to refer to Barker and Corbett as "the two Ronnies", while the writing team included Michael Palin, Terry Jones, Graham Chapman, and Eric Idle – every Monty Python member bar Terry Gilliam – as well as Marty Feldman and lead writer Antony Jay, who went on to create Yes, Minister.
(13) Moreover, a larger fraction of plasma VLDL is transformed into IDL and LDL, the latter representing the main plasma cholesterol carrier.
(14) Hagere Selam remains a modest place of mudwalled shops with corrugated roofs, cows, donkeys and sheep wandering unpaved streets and children idling away an afternoon at table football – a generation with no memory of the famine that killed hundreds of thousands and woke up the world.
(15) Epidemiological studies in humans suggest that IDL or remnant lipoproteins are predictors of the severity or progression of atherosclerosis.
(16) It would be idle to pretend that Cameron doesn't have talents as a leader.
(17) A chlorine sanitizer was circulated (5 min, 40 degrees C) and the unit containing sanitizing solution left idle overnight.
(18) Facebook Twitter Pinterest Either way, I love Jane for idly sticking two fingers up at the idea of a spa break in Rhodes or other emblems of “sophistication” being the only thing to aspire to.
(19) Bidders have spent an estimated £1m each on their bids but, according to one industry source, the process has stalled and franchise owners are being forced to retain expensive but idle bidding teams.
(20) The results indicate that a simple depletion of his-tRNA is not sufficient to elicit the response and suggest that idle ribosomes are required for regulation.