(1) The recent studies on the biosynthesis have clearly elucidated its mechanism at the gane levels, which reflects to the development of the inhibitors of the polyamine biosynthesis.
Yawn
Definition:
(v. i.) To open the mouth involuntarily through drowsiness, dullness, or fatigue; to gape; to oscitate.
(v. i.) To open wide; to gape, as if to allow the entrance or exit of anything.
(v. i.) To open the mouth, or to gape, through surprise or bewilderment.
(v. i.) To be eager; to desire to swallow anything; to express desire by yawning; as, to yawn for fat livings.
(n.) An involuntary act, excited by drowsiness, etc., consisting of a deep and long inspiration following several successive attempts at inspiration, the mouth, fauces, etc., being wide open.
(n.) The act of opening wide, or of gaping.
(n.) A chasm, mouth, or passageway.
Example Sentences:
(1) "We believe BAE's earnings could stagnate until the middle of this decade," said Goldman, which was also worried that performance fees on a joint fighter programme in America had been withheld by the Pentagon, and the company still had a yawning pension deficit.
(2) Morphine (0.1 to 5 micrograms), but not U-69,593 (5 micrograms), injected into the PVN 10 minutes before oxytocin or apomorphine, was found to be able to prevent penile erection and yawning induced by the unilateral PVN microinjection of oxytocin (10 ng) or apomorphine (50 ng).
(3) Apomorphine (Apo), a short acting dopamine (DA) receptor agonist, stimulates growth hormone (GH) secretion, decreases prolactin secretion, induces yawning, penile erections and other physiological effects in man.
(4) The present results demonstrate that either the presurgical drug treatment (desmethylimipramine and pentobarbital) or 7 days isolation was alone sufficient to reduce the yawning response to physostigmine and abolish its potentiation by nifedipine.
(5) It is tempting to visualise the yawning gap between the real-life equivalents of the fictional Chatsworth Estate, where Shameless is set, and Green Templeton College, Oxford, where Walker works.
(6) The yawning response was also assessed in normal young (less than 30 yrs; N = 16) and elderly (greater than 60 yrs; N = 12) volunteers.
(7) The present results suggest that calcium might be the second messenger which mediates the expression of penile erection and yawning induced by oxytocin.
(8) The occipital belly is also active during smiling and yawning, and can be active during the movements of the auricula.
(9) Very abruptly, he yawns, looks bored, and examines his sweatshirt.
(10) As well as being present in all mammals, yawning occurs, at least in its mandibular component, in all vertebrates.
(11) The difference between rats and monkeys in their yawning response to dopaminergic compounds is discussed.
(12) The pre-synaptical receptor's role had been suggested for a long time but actually yawning seems to be linked with a D1-D2 cooperation.
(13) In fact, the gender pay gap remains a yawning chasm.
(14) After pretreatment with mecamylamine, the apomorphine- and physostigmine-induced tongue protruding was inhibited and the duration of the yawning induced by the both drugs was shortened.
(15) Central administration of ACTH in rats induces yawning and stretching.
(16) The specific D-2 agonist LY 171555 elicited yawning, genital grooming, exploratory behavior, downward sniffing and licking but failed to induce gnawing even at high doses.
(17) The behavior categories included grooming, yawning, turning, nodding and gnawing, as well as snout contact and nonsnout contact variants of locomoting, rearing and sitting.
(18) As the dihydropyridine compounds affected apomorphine-induced yawning but not penile erection, and did not affect amphetamine-induced rotation or drug discrimination, it seems unlikely that they are affecting dopamine release in vivo.
(19) Since oxytocin is present not only in the neurohypophysis but also in other brain areas, our results suggest that oxytocin is implicated in the regulation of penile erection and yawning, and provide further evidence that oxytocin acts as a neuropeptide in the central nervous system.
(20) In the lesioned animals (in which the mean striatal dopamine depletion was 67%), the maximum yawning response rate was greatly attenuated with no evidence that the dose response curve was shifted in either direction.